Citation Impact
Citing Papers
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells
2014
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Selexipag for the Treatment of Pulmonary Arterial Hypertension
2015
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
1991 StandoutNature
Endothelin antagonism with bosentan: a review of potential applications
1999
PDF Cells Are a GABA-Responsive Wake-Promoting Component of the Drosophila Sleep Circuit
2008 StandoutNobel
Treatment of Pulmonary Arterial Hypertension
2004 Standout
The Glucocorticoid-responsive Gene Cascade
1997
Bradykinin-mediated effects of ACE inhibition
1992
Systemic sclerosis
2017 Standout
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice
2001 StandoutNobel
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
1990 Standout
Effect of Mibefradil, a T-Type Calcium Channel Blocker, on Morbidity and Mortality in Moderate to Severe Congestive Heart Failure
2000
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
Primary open-angle glaucoma
2004 Standout
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial
2003 Standout
Dissecting fibrosis: therapeutic insights from the small-molecule toolbox
2015
Altered inotropic response of endothelin-1 in cardiomyocytes from rats with isoproterenol-induced cardiomyopathy
1998
Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*
1993
Sleep Deprivation Effects on Circadian Clock Gene Expression in the Cerebral Cortex Parallel Electroencephalographic Differences among Mouse Strains
2008 StandoutNobel
A Randomized Trial of the Angiotensin-Receptor Blocker Valsartan in Chronic Heart Failure
2001 Standout
Endothelin antagonists
1999
Effects of angiotensin-II infusion at pressor and subpressor doses on endothelbv-1 plasma levels in healthy men
1997
Effect of Carvedilol on Survival in Severe Chronic Heart Failure
2001 Standout
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebocontrolled study
2001 Standout
The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness
2007
Idiopathic pulmonary fibrosis
2017 Standout
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
1991 Standout
Phosphorylation and Desensitization of Human Endothelin A and B Receptors
1997 StandoutNobel
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Value of cardiopulmonary exercise testing and big endothelin plasma levels to predict short-term prognosis of patients with chronic heart failure
1998
Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE)
1997 Standout
Structural and Functional Alteration of Blood Vessels Caused by Cigarette Smoking: An Overview of Molecular Mechanisms
2007
Enantioselective synthesis of almorexant via iridium-catalysed intramolecular allylic amidation
2013 StandoutNobel
Orexin Receptor Antagonists: A New Concept In CNS Disorders?
2010
Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension
2015 Standout
Endothelin receptor subtypes and their role in transmembrane signaling mechanisms
1995
Steroid hormone receptors: Many Actors in search of a plot
1995 Standout
Mammalian circadian signaling networks and therapeutic targets
2007
Endothelins: Pathophysiology and treatment implications in chronic heart failure
2005
Metastatic colonization by circulating tumour cells
2016 StandoutNature
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status
2008 StandoutNobel
Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension
2013
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis
2015 Standout
Myocilin Glaucoma
2002
Biomarkers in Heart Failure
2008 Standout
Macitentan: entry-into-humans study with a new endothelin receptor antagonist
2011
Gene Structure and Chromosomal Assignment of Mouse GITR, a Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Family
2000
Gene regulation by steroid hormones
1989 Standout
Calcium Channel Blockers in Heart Failure
1998
Ambrisentan, a Non‐peptide Endothelin Receptor Antagonist
2006
Usual Interstitial Pneumonia Can Be Detected in Transbronchial Biopsies Using Machine Learning
2017
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Endothelin-1 Is Involved in Norepinephrine-Induced Ventricular Hypertrophy In Vivo
1996
A Practical Synthesis of Renin Inhibitor MK-1597 (ACT-178882) via Catalytic Enantioselective Hydrogenation and Epimerization of Piperidine Intermediate
2011
Over One Hundred Peptide-Activated G Protein-Coupled Receptors Recognize Ligands with Turn Structure
2005
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Functional and Biochemical Analysis of Angiotensin II–Forming Pathways in the Human Heart
1997
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues
2018 StandoutNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Cardiovascular Mortality and Long-Term Exposure to Particulate Air Pollution
2003 Standout
Pulmonary Arterial Hypertension
2006
Phosphine Organocatalysis
2018 Standout
Inhalation toxicology of urban ambient particulate matter: acute cardiovascular effects in rats.
2001
Carvedilol, a cardiovascular drug, prevents vascular smooth muscle cell proliferation, migration, and neointimal formation following vascular injury.
1993
Biomedical Application of Orexin/Hypocretin Receptor Ligands in Neuroscience
2009
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Development and Evaluation of Endothelin-A Receptor (Radio)Ligands for Positron Emission Tomography
2011
Effect of Macitentan on the Development of New Ischemic Digital Ulcers in Patients With Systemic Sclerosis
2016
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Unusual Amino Acids in Medicinal Chemistry
2016
GITR Activation Induces an Opposite Effect on Alloreactive CD4+ and CD8+ T Cells in Graft-Versus-Host Disease
2004 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
1995 StandoutScience
One-Pot Phosphine-Catalyzed Syntheses of Quinolines
2012
Idiopathic Pulmonary Fibrosis
2018 Standout
Enalapril and Losartan Reduced Cardiac Mass and Improved Coronary Hemodynamics in SHR
1997
Prescribed drugs containing nitrogen heterocycles: an overview
2020 Standout
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Works of Patrick Hess being referenced
Design and optimization of new piperidines as renin inhibitors
2010
Selexipag: A Selective Prostacyclin Receptor Agonist that Does Not Affect Rat Gastric Function
2010
Promotion of sleep by targeting the orexin system in rats, dogs and humans
2007
Short-term endothelin receptor blockade with tezosentan has both immediate and long-term beneficial effects in rats with myocardial infarction
2002
Piperidine-based renin inhibitors: Upper chain optimization
2010
Pharmacology of Macitentan, an Orally Active Tissue-Targeting Dual Endothelin Receptor Antagonist
2008
Endothelin plays a role in the maintenance of blood pressure in normotensive guinea pigs
1994
Endothelin Mediates the Altered Renal Hemodynamics Associated with Experimental Congestive Heart Failure
2001
A Novel Genomic Signature with Translational Significance for Human Idiopathic Pulmonary Fibrosis
2014
Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan).
1994
The Discovery of N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N′-propylsulfamide (Macitentan), an Orally Active, Potent Dual Endothelin Receptor Antagonist
2012
Pharmacology of Tezosentan, New Endothelin Receptor Antagonist Designed for Parenteral Use
1999
Inhibition of converting enzyme and neointima formation after vascular injury in rabbits and guinea pigs.
1991
Hemodynamic Profile of Ro 40–5967 in Conscious Rats
1991
Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment that mediates a delayed secondary response to glucocorticoids in vivo.
1990
Delayed secondary glucocorticoid response elements. Unusual nucleotide motifs specify glucocorticoid receptor binding to transcribed regions of alpha 2u-globulin DNA.
1991
Effects of renin-angiotensin system blockade in guinea pigs.
1992
4-((R)-2-{[6-((S)-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel
2015
Effects of two angiotensin converting enzyme inhibitors and hydralazine on coronary circulation in hypertensive rats.
1991
Novel Benzo[1,4]diazepin-2-one Derivatives as Endothelin Receptor Antagonists
2004
Hormone withdrawal triggers a premature and sustained gene activation from delayed secondary glucocorticoid response elements.
1992