Citation Impact
Citing Papers
The Evolutionary Landscape of Alternative Splicing in Vertebrate Species
2012 Science
rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
2014 Standout
The human splicing code reveals new insights into the genetic determinants of disease
2014 Science
Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance
2014 StandoutNobel
RNA-seq differential expression studies: more sequence or more replication?
2013
Limits of long-term selection against Neandertal introgression
2019 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals
2014
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data
2020 StandoutNobel
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
De novo design and directed folding of disulfide-bridged peptide heterodimers
2022 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism
2014
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Evidence for conserved post-transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs
2012
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
An Expanded View of Complex Traits: From Polygenic to Omnigenic
2017 Standout
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
Lineage-Specific Changes in Biomarkers in Great Apes and Humans
2015 StandoutNobel
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
Hominoid-Specific De Novo Protein-Coding Genes Originating from Long Non-Coding RNAs
2012
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
A Comparison of Brain Gene Expression Levels in Domesticated and Wild Animals
2012 StandoutNobel
Rapid Turnover of Long Noncoding RNAs and the Evolution of Gene Expression
2012
Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome
2012
Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression
2017
Effective gene expression prediction from sequence by integrating long-range interactions
2021 StandoutNobel
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Comparative primate genomics: emerging patterns of genome content and dynamics
2014
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
A general framework for estimating the relative pathogenicity of human genetic variants
2014 Standout
Organization and Evolution of Brain Lipidome Revealed by Large-Scale Analysis of Human, Chimpanzee, Macaque, and Mouse Tissues
2015 StandoutNobel
Functional implications of Neandertal introgression in modern humans
2017
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
2015 StandoutNobel
Evolution and diversity of copy number variation in the great ape lineage
2013
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
A genome-wide map of hyper-edited RNA reveals numerous new sites
2014
Enhancer Evolution across 20 Mammalian Species
2015
Dynamics of DNA Methylation in Recent Human and Great Ape Evolution
2013
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Deep learning
2015 StandoutNatureNobel
Primate iPS cells as tools for evolutionary analyses
2014 StandoutNobel
Detecting differential usage of exons from RNA-seq data
2012
De novo design of tyrosine and serine kinase-driven protein switches
2021 StandoutNobel
The Human Condition—A Molecular Approach
2014 StandoutNobel
Estimating Gene Gain and Loss Rates in the Presence of Error in Genome Assembly and Annotation Using CAFE 3
2013 Standout
NONCODE 2016: an informative and valuable data source of long non-coding RNAs
2015
Human-Specific Transcriptional Networks in the Brain
2012
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Synthetic protein switches: design principles and applications
2014
N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
2015 StandoutNature
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Transcriptional response to hepatitis C virus infection and interferon‐alpha treatment in the human liver
2017
CADD: predicting the deleteriousness of variants throughout the human genome
2018 Standout
Detecting Natural Selection in Genomic Data
2013
Primate Transcript and Protein Expression Levels Evolve Under Compensatory Selection Pressures
2013 Science
Drift and conservation of differential exon usage across tissues in primate species
2013
Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness
2014 StandoutNobel
Analysis of Candidate Genes for Lineage-Specific Expression Changes in Humans and Primates
2014 StandoutNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
A circadian gene expression atlas in mammals: Implications for biology and medicine
2014 Standout
Deep learning of the tissue-regulated splicing code
2014
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Interpreting non-coding variation in complex disease genetics
2012
Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection
2022 StandoutNobel
Genetic Variation in Pan Species Is Shaped by Demographic History and Harbors Lineage-Specific Functions
2019
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
2013 Standout
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Works of Patrick Harrigan being referenced
Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control
2018
Building robust functionality in synthetic circuits using engineered feedback regulation
2013
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells
2019
Robust Synthetic Circuits for Two-Dimensional Control of Gene Expression in Yeast
2016