Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3–mediated pathway
2011
Design, Synthesis, Structure, and Gas (N 2 , Ar, CO 2 , CH 4 , and H 2 ) Sorption Properties of Porous Metal-Organic Tetrahedral and Heterocuboidal Polyhedra
2005 StandoutNobel
Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis
2005 Standout
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Die Totalsynthese von vermeintlichem Diazonamid A
2002
Total Synthesis of Palau’amine
2009
Chasing Molecules That Were Never There: Misassigned Natural Products and the Role of Chemical Synthesis in Modern Structure Elucidation
2005
Total Synthesis of Diazonamide A
2002
Diazonamide A and a Synthetic Structural Analog: Disruptive Effects on Mitosis and Cellular Microtubules and Analysis of Their Interactions with Tubulin
2003
In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8
2011
Necroptosis and its role in inflammation
2015 StandoutNature
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
Tandem reactions, cascade sequences, and biomimetic strategies in total synthesis
2003
The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans
2009
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Redox Economy in Organic Synthesis
2009
Tumor necrosis factor, cancer and anticancer therapy
2004
Pyrrole Aminoimidazole Alkaloid Metabiosynthesis with Marine Sponges Agelas conifera and Stylissa caribica
2012
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
2012 Standout
Marine natural products
1990 Standout
Shared Principles in NF-κB Signaling
2008 Standout
Drug development from marine natural products
2008 Standout
The rational design of potential chemotherapeutic agents: Synthesis of bryostatin analogues
1999
Crystal structure refinement withSHELXL
2014 Standout
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Marine pharmacology in 2003–2004: Anti-tumour and cytotoxic compounds
2006
The influence of natural products upon drug discovery (Antiquity to late 1999)
2000
Treatment parameters modulating regression of human melanoma xenografts by an antibody–drug conjugate (CR011-vcMMAE) targeting GPNMB
2007
Nitrogen and Hydrogen Adsorption by an Organic Microporous Crystal
2009
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
2012 Standout
Total synthesis of (−)-ulapualide A, a novel tris-oxazole macrolide from marine nudibranchs, based on some biosynthesis speculation
2008
Spongistatin 1: a new chemosensitizing marine compound that degrades XIAP
2008
Enantioselective Synthesis of (+)‐Monobromophakellin and (+)‐Phakellin: A Concise Phakellin Annulation Strategy Applicable to Palau'amine
2008
Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids
2011
A long-awaited merger of the pathways mediating host defence and programmed cell death
2014
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
2013
Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α
2013
Immunity, Inflammation, and Cancer
2010 Standout
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
2011
C–H functionalization logic in total synthesis
2011
IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
2007
Cascade Reactions in Total Synthesis
2006 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
The exploration of macrocycles for drug discovery — an underexploited structural class
2008
Total Synthesis of Palau’amine
2009
The chemistry and biology of the bryostatin antitumour macrolides
2002
Structure validation in chemical crystallography
2009 Standout
Construction of the Complete Aromatic Core of Diazonamide A by a Novel Hetero Pinacol Macrocyclization Cascade Reaction
2001
Genome-wide silencing in Drosophila captures conserved apoptotic effectors
2009 Nature
The Second Total Synthesis of Diazonamide A
2003
The synthetic challenge of diazonamide A, a macrocyclic indole bis-oxazole marine natural product
2008
Tumour necrosis factor and cancer
2009
Living with death: the evolution of the mitochondrial pathway of apoptosis in animals
2008
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
2011
Exploration of the interrupted Fischer indolization reaction
2010
The Pursuit of Palau'amine
2007
XIAP discriminates between type I and type II FAS-induced apoptosis
2009 Nature
Cancer-related inflammation
2008 StandoutNature
IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis
2007
Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells
2013
Total Synthesis of (±)‐Axinellamines A and B
2008
NEMO and RIP1 Control Cell Fate in Response to Extensive DNA Damage via TNF-α Feedforward Signaling
2011
TNF-α Induces Two Distinct Caspase-8 Activation Pathways
2008
Regulation of death receptor signaling by the ubiquitin system
2009
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Diving for drugs: tunicate anticancer compounds
2012
Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products
2010 Standout
Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
2016
ExCage
2014 StandoutNobel
Exceptional Thermal Stability in a Supramolecular Organic Framework: Porosity and Gas Storage
2010 StandoutNobel
Clues from cell metabolism
2010 StandoutNatureNobel
Late-Stage Intermolecular CH Activation for Lead Diversification: A Highly Chemoselective Oxyfunctionalization of the C-9 Position of Potent Bryostatin Analogues
2004
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Search and Discovery Strategies for Biotechnology: the Paradigm Shift
2000
Control of Life-or-Death Decisions by RIP1 Kinase
2013
Marine Natural Products and Related Compounds in Clinical and Advanced Preclinical Trials
2004
Radicals: Reactive Intermediates with Translational Potential
2016
The Second Total Synthesis of Diazonamide A
2003
Synthesis and biological evaluation of a new class of bryostatin analogues: the role of the C20 substituent in protein kinase C binding
2000
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
The Practical Synthesis of a Novel and Highly Potent Analogue of Bryostatin
2002
Enantioselective organocatalytic construction of pyrroloindolines by a cascade addition–cyclization strategy: Synthesis of (–)-flustramine B
2004
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Single-Crystal Structure of a Covalent Organic Framework
2013 StandoutNobel
An Interrupted Fischer Indolization Approach toward Fused Indoline-Containing Natural Products
2009
Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
2009
Reticulating 1D Ribbons into 2D Covalent Organic Frameworks by Imine and Imide Linkages
2020 StandoutNobel
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
Diazonamides C–E, new cytotoxic metabolites from the ascidian Diazona sp.
2008
A Selective Account of Effective Paradigms and Significant Outcomes in the Discovery of Inspirational Marine Natural Products
2009
Synthesis of the Diazonamide A Macrocyclic Core via a Dieckmann-Type Cyclization
2001
Utilizing the Power of Microbial Genetics to Bridge the Gap Between the Promise and the Application of Marine Natural Products
2005
A Concise, Selective Synthesis of the Polyketide Spacer Domain of a Potent Bryostatin Analogue
2003
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants
2019 StandoutNobel
A Biomimetic Route for Construction of the [4+2] and [3+2] Core Skeletons of Dimeric Pyrrole–Imidazole Alkaloids and Asymmetric Synthesis of Ageliferins
2012
Chemistry and Biology of Diazonamide A: First Total Synthesis and Confirmation of the True Structure
2004
Impact of Marine Drugs on Cytoskeleton-Mediated Reproductive Events
2010
Domino Reactions in Organic Synthesis
2006 Standout
Die Jagd auf Palau'amin
2007
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Die Jagd auf Moleküle, die nie existiert haben: Falsch zugeordnete Naturstoffstrukturen und die Rolle der chemischen Synthese in der modernen Strukturaufklärung
2005
Total Synthesis of Dimeric Pyrrole−Imidazole Alkaloids: Sceptrin, Ageliferin, Nagelamide E, Oxysceptrin, Nakamuric Acid, and the Axinellamine Carbon Skeleton
2007
Palladiumkatalysierte Kreuzkupplungen in der Totalsynthese
2005
Enantioselective Total Syntheses of (−)-Palau’amine, (−)-Axinellamines, and (−)-Massadines
2011
Azonazine, a Novel Dipeptide from a Hawaiian Marine Sediment-Derived Fungus, Aspergillus insulicola
2010
Effects of Functionalization, Catenation, and Variation of the Metal Oxide and Organic Linking Units on the Low-Pressure Hydrogen Adsorption Properties of Metal−Organic Frameworks
2006 StandoutNobel
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Calcium l -Lactate Frameworks as Naturally Degradable Carriers for Pesticides
2017 StandoutNobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Mitochondrial Dysfunction Confers Resistance to Multiple Drugs inCaenorhabditis elegans
2010
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Scalable, Stereocontrolled Total Syntheses of (±)-Axinellamines A and B
2011
On the synthesis of pyrinodemin A. Part 1: The location of the olefin
2004
Aryl-fluorosulfate-based Lysine Covalent Pan-Inhibitors of Apoptosis Protein (IAP) Antagonists with Cellular Efficacy
2019
Pharmacological Developments Obtained from Marine Natural Products and Current Pipeline Perspective
2011
Photochemical Reactions as Key Steps in Organic Synthesis
2008
Evolution of water structures in metal-organic frameworks for improved atmospheric water harvesting
2021 StandoutScienceNobel
Nature: a vital source of leads for anticancer drug development
2009
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Photo-Fries rearrangement for the synthesis of the diazonamide macrocycle
2001
Catalytic Asymmetric Epoxidation of α-Branched Enals
2010 StandoutNobel
Cultivation-independent approaches to investigate the chemistry of marine symbiotic bacteria
2009
Strategies for the Diversity-Oriented Synthesis of Macrocycles
2019
High Methane Storage Working Capacity in Metal–Organic Frameworks with Acrylate Links
2016 StandoutNobel
Single-crystal structure validation with the programPLATON
2003 Standout
Sequential Transformations in Organic Chemistry: A Synthetic Strategy with a Future
1993
Enantioselective Synthesis of (+)‐Monobromophakellin and (+)‐Phakellin: A Concise Phakellin Annulation Strategy Applicable to Palau'amine
2008
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
IAP inhibitors enhance co-stimulation to promote tumor immunity
2010
Total Synthesis of Bryostatin 1
2010
A New Synthetic Approach to the C Ring of Known as Well as Novel Bryostatin Analogues
2003
The Heck Reaction as a Sharpening Stone of Palladium Catalysis
2000 Standout
Synthesis and biological evaluation of bryostatin analogues: the role of the A-ring
2000
Chiral Dialkylaminopyridine Catalysts in Asymmetric Synthesis
2007
Self-Accelerating CO Sorption in a Soft Nanoporous Crystal
2013 StandoutScienceNobel
An Expedient Formal Total Synthesis of (−)-Diazonamide A via a Powerful, Stereoselective O-Aryl to C-Aryl Migration To Form the C10 Quaternary Center
2007
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Total Synthesis of (±)‐Axinellamines A and B
2008
High Methane Storage Capacity in Aluminum Metal–Organic Frameworks
2014 StandoutNobel
Sequentielle Transformationen in der Organischen Chemie eine Synthesestrategie mit Zukunft
1993
Works of Patrick G. Harran being referenced
Total Synthesis of Nominal Diazonamides-Part 1: Convergent Preparation of the Structure Proposed for (−)-Diazonamide A
2001
Total Synthesis of Nominal Diazonamides-Part 2: On the True Structure and Origin of Natural Isolates
2001
Electrolytic Macrocyclizations: Scalable Synthesis of a Diazonamide‐Based Drug Development Candidate
2015
Autocrine TNFα Signaling Renders Human Cancer Cells Susceptible to Smac-Mimetic-Induced Apoptosis
2007
Synthetic (±)‐Axinellamines Deficient in Halogen
2012
Exploring Symmetry-Based Logic for a Synthesis of Palau’amine
2009
Synthetic seco Forms of (−)-Diazonamide A
2001
Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel–Dreyer chromatography
2003
A Concise and Flexible Total Synthesis of (−)‐Diazonamide A
2003
Spirocycloisomerization of Tethered Alkylidene Glycocyamidines: Synthesis of a Base Template Common to the Palau'amine Family of Alkaloids
2004
Template-induced macrocycle diversity through large ring-forming alkylations of tryptophan
2013
Synthetic seco Forms of (−)-Diazonamide A
2001
Synthetic Application of the Alder-Bong Reaction: Stereoselective Construction of the Methanohydroazulene Framework
1990
The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1
1998
Stereocontrol in Pinacol Ring-Contraction of Cyclopeptidyl Glycols: The Diazonamide C10 Problem
2000
Synthesis of the First Members of a New Class of Biologically Active Bryostatin Analogues
1998
Concerning the phakellin substructure of palau’amine
2006
Total Synthesis of Nominal Diazonamides—Part 2: On the True Structure and Origin of Natural Isolates
2001
Methods to initiate synthetic re-structuring of peptides
2003
Total Synthesis of Nominal Diazonamides—Part 1: Convergent Preparation of the Structure Proposed for (−)-Diazonamide A
2001
The chemistry-medicine continuum: Synthetic, computer, spectroscopic and biological studies on new chemotherapeutic leads
1998
A Concise and Flexible Total Synthesis of (−)‐Diazonamide A
2003
Preview
2001
Macrocyclic Triarylethylenes via Heck Endocyclization: A System Relevant to Diazonamide Synthesis
1998
Stereocontrol in Pinacol Ring-Contraction of Cyclopeptidyl Glycols: The Diazonamide C10 Problem
2000
Spirocycloisomerization of Tethered Alkylidene Glycocyamidines: Synthesis of a Base Template Common to the Palau'amine Family of Alkaloids
2004
Synthesis and biological evaluation of fully synthetic bryostatin analogues
1998
Template-constrained macrocyclic peptides prepared from native, unprotected precursors
2013
A missense mutation in Caenorhabditis elegans prohibitin 2 confers an atypical multidrug resistance
2006
Acid Promoted Cinnamyl Ion Mobility within Peptide Derived Macrocycles
2008
A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death
2004 Science
Diazonamide toxins reveal an unexpected function for ornithine δ-amino transferase in mitotic cell division
2007
Large ring-forming alkylations provide facile access to composite macrocycles
2015
Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity
2007