Standout Papers

Drosophila CRY Is a Deep Brain Circadian Photoreceptor 2000 2026 2008 2017 335
  1. Drosophila CRY Is a Deep Brain Circadian Photoreceptor (2000)
    Patrick Emery, Ralf Stanewsky et al. Neuron
  2. Drosophila Clock Can Generate Ectopic Circadian Clocks (2003)
    Jie Zhao, Valerie L. Kilman et al. Cell
  3. Roles of the Two Drosophila CRYPTOCHROME Structural Domains in Circadian Photoreception (2004)
    Ania Busza, Michael Rosbash et al. Science
  4. Wild-Type Circadian Rhythmicity Is Dependent on Closely Spaced E Boxes in the Drosophila timelessPromoter (2001)
    Michael J. McDonald, Michael Rosbash et al. Molecular and Cellular Biology
  5. Stopping Time: The Genetics of Fly and Mouse Circadian Clocks (2001)
    Ravi Allada, Patrick Emery et al. Annual Review of Neuroscience
  6. A unique circadian-rhythm photoreceptor (2000)
    Patrick Emery, Ralf Stanewsky et al. Nature
  7. CRY, a Drosophila Clock and Light-Regulated Cryptochrome, Is a Major Contributor to Circadian Rhythm Resetting and Photosensitivity (1998)
    Patrick Emery, W. Venus So et al. Cell
  8. A Constant Light-Genetic Screen Identifies KISMET as a Regulator of Circadian Photoresponses (2009)
    Raphaëlle Dubruille, Alejandro Murad et al. PLoS Genetics
  9. The cryb Mutation Identifies Cryptochrome as a Circadian Photoreceptor in Drosophila (1998)
    Ralf Stanewsky, Maki Kaneko et al. Cell

Citation Impact

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Time Flies for Drosophila
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Circadian timekeeping and output mechanisms in animals
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A quadruple photoreceptor mutant still keeps track of time
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Circadian rhythms: Something to cry about?
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The C Termini of Arabidopsis Cryptochromes Mediate a Constitutive Light Response
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A Role for the Segment Polarity Gene shaggy/GSK-3 in the Drosophila Circadian Clock
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The neuroarchitecture of the circadian clock in the brain of Drosophila melanogaster
2003
The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator
2002 Standout
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The cryptochromes.
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Control of Daily Transcript Oscillations in Drosophila by Light and the Circadian Clock
2006
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DNA photolyases and cryptochromes
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Light Activates Output from Evening Neurons and Inhibits Output from Morning Neurons in the Drosophila Circadian Clock
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Cryptochrome is present in the compound eyes and a subset of Drosophila's clock neurons
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A Self-Sustaining, Light-Entrainable Circadian Oscillator in the Drosophila Brain
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Drosophila GPCR Han Is a Receptor for the Circadian Clock Neuropeptide PDF
2005
The Doubletime and CKII Kinases Collaborate to Potentiate Drosophila PER Transcriptional Repressor Activity
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Peptidergic clock neurons in Drosophila: Ion transport peptide and short neuropeptide F in subsets of dorsal and ventral lateral neurons
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A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
1999 Nature
Light Induction of a Vertebrate Clock Gene Involves Signaling through Blue-Light Receptors and MAP Kinases
2002 StandoutNobel
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2000 StandoutNobel
Circadian Pacemaker Neurons Transmit and Modulate Visual Information to Control a Rapid Behavioral Response
2005
Membrane electrical excitability is necessary for the free‐running larval Drosophila circadian clock
2004
Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism
2009
The circadian system of Drosophila melanogaster and its light input pathways
2002
CLOCK:BMAL1 is a pioneer-like transcription factor
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The Cryptochrome Blue Light Receptors
2010
Photoentrainment in Mammals: A Role for Cryptochrome?
1999
The F-box protein Slimb controls the levels of clock proteins Period and Timeless
2002 Nature
Role of Molecular Oscillations in Generating Behavioral Rhythms in Drosophila
2001
Genetics and molecular biology of rhythms in Drosophila and other insects
2003 StandoutNobel
PLEIOTROPIC EFFECTS OF CRYPTOCHROMES 1 AND 2 ON FREE-RUNNING AND LIGHT-ENTRAINED MURINE CIRCADIAN RHYTHMS
2002 StandoutNobel
The Drosophila melanogaster circadian pacemaker circuit
2008
Bacterial cryptochrome and photolyase: characterization of two photolyase-like genes of Synechocystis sp. PCC6803
2000
Rhythm Defects Caused by Newly Engineered Null Mutations in Drosophila's cryptochrome Gene
2007 StandoutNobel
Development and morphology of the clock‐gene‐expressing lateral neurons of Drosophila melanogaster
2006
Role of Posttranscriptional Regulation in Orcadian Clocks: Lessons formDrosophila
1999
PDF and cAMP enhance PER stability in Drosophila clock neurons
2014 StandoutNobel
Redox Control of Protein Conformation in Flavoproteins
2009
Accelerated Degradation of perS Protein Provides Insight into Light-Mediated Phase Shifting
2013 StandoutNobel
PDF neuron firing phase-shifts key circadian activity neurons in Drosophila
2014 StandoutNobel
Circadian Organization of Behavior and Physiology in Drosophila
2010
Cryptochrome: The Second Photoactive Pigment in the Eye and Its Role in Circadian Photoreception
2000 StandoutNobel
Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice
2001 StandoutNobel
Molecular Components of the Circadian System in Drosophila
2001
Expression of the Blue-Light Receptor Cryptochrome in the Human Retina
2003 StandoutNobel
Circadian rhythms in a nutshell
2000
takeout, a Novel DrosophilaGene under Circadian Clock Transcriptional Regulation
2000 StandoutNobel
Blue-Light Photoreceptors in Higher Plants
1999
Tales from the Crypt(ochromes)
2002
The circadian output gene takeout is regulated by Pdp1ε
2010
Direct Association between Mouse PERIOD and CKIε Is Critical for a Functioning Circadian Clock
2003
Flavin reduction activates Drosophila cryptochrome
2013
Genetic Analysis of Ectopic Circadian Clock Induction in Drosophila
2009
Purification and characterization of the Danaus plexippus cryptochromes
2019
DOUBLETIME Plays a Noncatalytic Role To Mediate CLOCK Phosphorylation and Repress CLOCK-Dependent Transcription within the Drosophila Circadian Clock
2009
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
Circadian Photoreception in Drosophila: Functions of Cryptochrome in Peripheral and Central Clocks
2001
Cryptochromes: enabling plants and animals to determine circadian time.
2003
Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila
2010 StandoutNobel
Synergic Entrainment of Drosophila’s Circadian Clock by Light and Temperature
2009
Molecular Genetics of Circadian Rhythms in Mammals
2000
TheDrosophila double-timeSMutation Delays the Nuclear Accumulation ofperiodProtein and Affects the Feedback Regulation ofperiodmRNA
2001
Circadian Synchronization and Rhythmicity in Larval Photoperception-Defective Mutants of Drosophila
2004
Interlocked Feedback Loops Within the Drosophila Circadian Oscillator
1999 Science
Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana
2004 Nobel
Molecular Bases of Circadian Rhythms
2001
The Signaling Mechanism of Arabidopsis CRY1 Involves Direct Interaction with COP1
2001
Cryptochromes: Blue Light Receptors for Plants and Animals
1999 Science
Veela defines a molecular link between Cryptochrome and Timeless in the light-input pathway to Drosophila 's circadian clock
2006
Tripping the Light Fantastic: Blue-Light Photoreceptors as Examples of Environmentally Modulated Protein−Protein Interactions
2010
Reaction mechanism of Drosophila cryptochrome
2010 StandoutNobel
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Photic Signaling by Cryptochrome in the Drosophila Circadian System
2001
Circadian Photoperception
2001
An Extraretinally Expressed Insect Cryptochrome with Similarity to the Blue Light Photoreceptors of Mammals and Plants
1999
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Transcription Regulation within the Circadian Clock: The E-box and Beyond
2004
Differential regulation of circadian pacemaker output by separate clock genes in Drosophila
2000 StandoutNobel
Cryptochromes
2003
Involvement of the period Gene in Developmental Time-Memory: Effect of the perShort Mutation on Phase Shifts Induced by Light Pulses Delivered to Drosophila Larvae
2000 StandoutNobel
The Blue-Light Photoreceptor CRYPTOCHROME Is Expressed in a Subset of Circadian Oscillator Neurons in the Drosophila CNS
2008
Comparative Photochemistry of Animal Type 1 and Type 4 Cryptochromes
2009 StandoutNobel
A resetting signal between Drosophila pacemakers synchronizes morning and evening activity
2005 StandoutNatureNobel
The cancer connection
2002 StandoutNatureNobel
The Cryptochromes: Blue Light Photoreceptors in Plants and Animals
2011
Metabolism and the Control of Circadian Rhythms
2002
Resetting of Circadian Time in Peripheral Tissues by Glucocorticoid Signaling
2000 StandoutScience
Role of Structural Plasticity in Signal Transduction by the Cryptochrome Blue-Light Photoreceptor
2005 StandoutNobel
Light-Dependent Sequestration of TIMELESS by CRYPTOCHROME
1999 Science
Finding New Clock Components: Past and Future
2004
Light-arousal and circadian photoreception circuits intersect at the large PDF cells of the Drosophila brain
2008 StandoutNobel
Sequential Nuclear Accumulation of the Clock Proteins Period and Timeless in the Pacemaker Neurons ofDrosophila melanogaster
2002 StandoutNobel
Influence of the period -dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster
2002
Cryptochrome, Compound Eyes, Hofbauer-Buchner Eyelets, and Ocelli Play Different Roles in the Entrainment and Masking Pathway of the Locomotor Activity Rhythm in the Fruit Fly Drosophila Melanogaster
2003
Protein kinase A and casein kinases mediate sequential phosphorylation events in the circadian negative feedback loop
2007
Characterization of Blue-light and Developmental Regulation of the Photolyase gene phr1 in Trichoderma harzianum
2000
The Evolution of Flavin-Binding Photoreceptors: An Ancient Chromophore Serving Trendy Blue-Light Sensors
2012
A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity
2006 StandoutNobel
The locomotor activity rhythm of Drosophila melanogaster is controlled by a dual oscillator system
2001
Analysis of functional neuronal connectivity in theDrosophilabrain
2012
Cryptochrome Structure and Signal Transduction
2003
Molecular Mechanism and Cellular Distribution of Insect Circadian Clocks
2000
Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2
1999 StandoutNobel
Circadian neuron feedback controls the Drosophila sleep–activity profile
2016 StandoutNatureNobel
Derepression of the NC80 motif is critical for the photoactivation of Arabidopsis CRY2
2007
Hofbauer-Buchner Eyelet Affects Circadian Photosensitivity and Coordinates TIM and PER Expression in Drosophila Clock Neurons
2007
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
GENETICS OF THE MAMMALIAN CIRCADIAN SYSTEM: Photic Entrainment, Circadian Pacemaker Mechanisms, and Posttranslational Regulation
2000

Works of Patrick Emery being referenced

A Role for Drosophila ATX2 in Activation of PER Translation and Circadian Behavior
2013 Science
CRY, a Drosophila Clock and Light-Regulated Cryptochrome, Is a Major Contributor to Circadian Rhythm Resetting and Photosensitivity
1998 StandoutNobel
The cryb Mutation Identifies Cryptochrome as a Circadian Photoreceptor in Drosophila
1998 StandoutNobel
Drosophila CRY Is a Deep Brain Circadian Photoreceptor
2000 StandoutNobel
GW182 Controls Drosophila Circadian Behavior and PDF-Receptor Signaling
2013
Studying circadian rhythms in Drosophila melanogaster
2014
Circadian Rhythm of Temperature Preference and Its Neural Control in Drosophila
2012
Cryptochromes Define a Novel Circadian Clock Mechanism in Monarch Butterflies That May Underlie Sun Compass Navigation
2008
Morning and Evening Oscillators Cooperate to Reset Circadian Behavior in Response to Light Input
2014
Light and Temperature Control the Contribution of Specific DN1 Neurons to Drosophila Circadian Behavior
2010
Drosophila Clock Can Generate Ectopic Circadian Clocks
2003 StandoutNobel
A Plastic Clock: How Circadian Rhythms Respond to Environmental Cues in Drosophila
2008
A Subset of Dorsal Neurons Modulates Circadian Behavior and Light Responses in Drosophila
2007
Interactions between Circadian Neurons Control Temperature Synchronization ofDrosophilaBehavior
2007
A unique circadian-rhythm photoreceptor
2000 StandoutNatureNobel
Roles of the Two Drosophila CRYPTOCHROME Structural Domains in Circadian Photoreception
2004 StandoutScienceNobel
Wild-Type Circadian Rhythmicity Is Dependent on Closely Spaced E Boxes in the Drosophila timelessPromoter
2001 StandoutNobel
Stopping Time: The Genetics of Fly and Mouse Circadian Clocks
2001 StandoutNobel
Ectopic CRYPTOCHROME Renders TIM Light Sensitive in the Drosophila Ovary
2006
Rankless by CCL
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