Citation Impact
Citing Papers
Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver
2014
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
2022 Standout
GlutathioneS-Transferase-Mediated Mutagenicity of Trihalomethanes inSalmonella typhimurium:Contrasting Results with Bromodichloromethane and Chloroform
1997
Analysis of in vivo and in vitro DNA strand breaks from trihalomethane exposure.
2004
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
2008 Standout
Human induced pluripotent stem cells and their use in drug discovery for toxicity testing
2013
The multitude and diversity of environmental carcinogens
2007 StandoutNobel
Identification of the molecular basis of doxorubicin-induced cardiotoxicity
2012 Standout
Vinyl Chloride—A Classical Industrial Toxicant of New Interest
2005
Structural Alerts, Reactive Metabolites, and Protein Covalent Binding: How Reliable Are These Attributes as Predictors of Drug Toxicity?
2009
Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
2014 Standout
Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
2012
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans
2016
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Drug-mediated toxicity: illuminating the ‘bad’ in the test tube by means of cellular assays?
2012
Drug development from marine natural products
2008 Standout
Organoid Models and Applications in Biomedical Research
2015 Standout
Lifestyle-related factors and environmental agents causing cancer: An overview
2007 StandoutNobel
Machine learning for molecular and materials science
2018 StandoutNature
Hepatotoxicity and Mechanism of Action of Haloalkanes: Carbon Tetrachloride as a Toxicological Model
2003 Standout
Formaldehyde and Glutaraldehyde and Nasal Cytotoxicity: Case Study Within the Context of the 2006 IPCS Human Framework for the Analysis of a Cancer Mode of Action for Humans
2006
Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association
2022 Standout
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Physicochemical drug properties associated within vivotoxicological outcomes: a review
2009
How to improve R&D productivity: the pharmaceutical industry's grand challenge
2010 Standout
Proceedings of the Hydrogen Sulfide Health Research and Risk Assessment Symposium October 31-November 2, 2000
2005
A Comparison of Whole Genome Gene Expression Profiles of HepaRG Cells and HepG2 Cells to Primary Human Hepatocytes and Human Liver Tissues
2010
Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes
2011
Induction of DNA strand breaks by trihalomethanes in primary human lung epithelial cells
2003
The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates
2007
Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation
2013
Drug discovery for a new generation of covalent drugs
2012
Microfluidic organs-on-chips
2014 Standout
Disposition of Bromodichloromethane in Humans Following Oral and Dermal Exposure
2007
In vitro biotransformation and genotoxicity of the drinking water disinfection byproduct bromodichloromethane: DNA binding mediated by glutathione transferase theta 1-1
2004
A simple practice guide for dose conversion between animals and human
2016 Standout
Idiosyncratic drug hepatotoxicity
2005
Hydrogen sulphide and its therapeutic potential
2007 Standout
The induction of aberrant crypt foci (ACF) in the colons of rats by trihalomethanes administered in the drinking water
2002
Estimating the Risk of Drug-Induced Proarrhythmia Using Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes
2011
Primary brain tumours in adults
2012 Standout
Drug development for CNS disorders: strategies for balancing risk and reducing attrition
2007
Hepatotoxicity and metabolism of trabectedin: a literature review
2005
THE PRACTICE OF EXPOSURE ASSESSMENT: A STATE-OF-THE-ART REVIEW
2000 Standout
Component-Based and Whole-Mixture Techniques for Addressing the Toxicity Of Drinking-Water Disinfection By-Product Mixtures
2004
Evolving concepts in liver tissue modeling and implications forin vitrotoxicology
2008
Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro
2016
Recovery of Rhodococcus biosurfactants using methyl tertiary-butyl ether extraction
2001
Toxicology for the twenty-first century
2009 StandoutNature
Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research
2007 Standout
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human
2009
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose
2004
Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury
2008
Inhibition of Hepatobiliary Transport as a Predictive Method for Clinical Hepatotoxicity of Nefazodone
2006
Microengineered Liver Tissues for Drug Testing
2015
An analysis of the attrition of drug candidates from four major pharmaceutical companies
2015 Standout
Effect of Trihalomethanes on Cell Proliferation and DNA Methylation in Female B6C3F1 Mouse Liver
2000
3D Printing of Tissue Engineered Constructs for In Vitro Modeling of Disease Progression and Drug Screening
2016
Compressing drug development timelines in oncology using phase '0' trials
2007
Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans
2012
Engineering Adolescence
2014 Standout
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Comparison of Five In Vitro Digestion Models To Study the Bioaccessibility of Soil Contaminants
2002 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Drinking Water Disinfection Byproducts (DBPs) and Human Health Effects: Multidisciplinary Challenges and Opportunities
2017 Standout
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
A critical assessment of modeling safety-related drug attrition
2013
Water Analysis: Emerging Contaminants and Current Issues
2014 Standout
Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1
2015
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Cardiac troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity
2007
Human and Animal Dirofilariasis: the Emergence of a Zoonotic Mosaic
2012 Standout
Cell and tissue engineering for liver disease
2014
admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties
2012 Standout
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
2017 StandoutNobel
Toward an evidence-based toxicology
2006
Carcinogenicity of Bromodichloromethane Administered in Drinking Water to Male F344/N Rats and B6C3F1 Mice
2002
Plastics, the environment and human health: current consensus and future trends
2009 Standout
Assessing exposure in epidemiologic studies to disinfection by-products in drinking water: report from an international workshop.
2002
The Liver Toxicity Knowledge Base (LKTB) and drug-induced liver injury (DILI) classification for assessment of human liver injury
2017
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
PubChem 2023 update
2022 Standout
Combination therapy in combating cancer
2017 Standout
Genomics, proteomics and metabonomics in toxicology: hopefully not ‘fashionomics’
2004
Formaldehyde in the Indoor Environment
2010 Standout
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Electronic Cigarettes
2014
Phase I Trial of MS-275, a Histone Deacetylase Inhibitor, Administered Weekly in Refractory Solid Tumors and Lymphoid Malignancies
2007
Micro- and Macroelemental Composition and Safety Evaluation of the NutraceuticalMoringa oleiferaLeaves
2014
Modeling Liver-Related Adverse Effects of Drugs Using kNearest Neighbor Quantitative Structure−Activity Relationship Method
2010
Organization of a taxonomically diverse lizard assemblage in Amazonian Ecuador
1996
Dogs and monkeys in preclinical drug development: the challenge of reducing and replacing
2013
Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview
2015 Standout
Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research
2010
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
2012 Standout
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Additive manufacturing (3D printing): A review of materials, methods, applications and challenges
2018 Standout
Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species
2009
The Essential Medicinal Chemistry of Curcumin
2017 Standout
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
Development and application of a human PBPK model for bromodichloromethane to investigate the impacts of multi‐route exposure
2015
Methods for Identifying a Default Cross-Species Scaling Factor
2006
Phylogenies and Community Ecology
2002 Standout
Works of Patrick D. Lilly being referenced
Benchmark Dose Risk Assessment for Formaldehyde Using Airflow Modeling and a Single‐Compartment, DNA‐Protein Cross‐Link Dosimetry Model to Estimate Human Equivalent Doses
2003
Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes
1998
Simulation Modeling of the Tissue Disposition of Formaldehyde to Predict Nasal DNA-Protein Cross-Links in Fischer 344 Rats, Rhesus Monkeys, and Humans
2000
Effect of subchronic corn oil gavage on the acute toxicity of orally administered bromodichloromethane
1996
A Physiologically Based Pharmacokinetic Description of the Oral Uptake, Tissue Dosimetry, and Rates of Metabolism of Bromodichloromethane in the Male Rat
1998
Non-clinical safety and pharmacokinetic evaluations of propylene glycol aerosol in Sprague-Dawley rats and Beagle dogs
2011
Dose-Dependent Vehicle Differences in the Acute Toxicity of Bromodichloromethane
1994
Trihalomethane Comparative Toxicity: Acute Renal and Hepatic Toxicity of Chloroform and Bromodichloromethane Following Aqueous Gavage,
1997
Concordance of the Toxicity of Pharmaceuticals in Humans and in Animals
2000 Standout
The Effects of Duration of Exposure to Acidic Conditions on Survival of Bufo americanus Embryos
1992
Physiologically based estimation of in vivo rates of bromodichloromethane metabolism
1997