Citation Impact
Citing Papers
Cells lying on a bed of microneedles: An approach to isolate mechanical force
2003 Standout
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation
2003
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
Regulated import and degradation of a cytosolic protein in the yeast vacuole
1991 StandoutNatureNobel
The Bovine Calpastatin Gene Promoter and a New N-terminal Region of the Protein Are Targets for cAMP-dependent Protein Kinase Activity
1998
cAMP responsiveness of the bovine calpastatin gene promoter
1998
Mechanisms of Thrombus Formation
2008 Standout
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
Crystal structure of calpain reveals the structural basis for Ca2+-dependent protease activity and a novel mode of enzyme activation
1999
MYC on the Path to Cancer
2012 Standout
Dissociation of m-Calpain Subunits Occurs after Autolysis of the N-Terminus of the Catalytic Subunit, and Is Not Required for Activation
2001
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Calcium signalling: dynamics, homeostasis and remodelling
2003 Standout
Functional Defects of a Muscle-specific Calpain, p94, Caused by Mutations Associated with Limb-Girdle Muscular Dystrophy Type 2A
1998
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2004 StandoutNature
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Forming a Multinucleated Cell: Molecules That Regulate Myoblast Fusion
2004
Wnt5A Activates the Calpain-Mediated Cleavage of Filamin A
2009
Domain structure of calpain: mapping the binding site for calpastatin
1994
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
Effects of thiol protease inhibitors on myoblast fusion and myofibril assembly in vitro
1998
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Microinjection of Calpastatin Inhibits Fusion in Myoblasts
1999
A New Subfamily of Vertebrate Calpains Lacking a Calmodulin-Like Domain: Implications for Calpain Regulation and Evolution
1997
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia
1999 StandoutNobel
'Oxidation Inhibits Substrate Proteolysis by Calpain I but Not Autolysis
1997
Mechanically Activated Ion Channels
2015 StandoutNobel
A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
2011 Standout
Reduced Cell Migration and Disruption of the Actin Cytoskeleton in Calpain-deficient Embryonic Fibroblasts
2001
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
2011 StandoutNature
The structural and functional diversity of dystrophin
1993
Some properties of the millimolar Ca2+-dependent proteinase from bovine cardiac muscle
1988
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
2010 Standout
Preference of calcium‐dependent interactions between calmodulin‐like domains of calpain and calpastatin subdomains
1995
Calpains Are Activated in Necrotic Fibers from mdx Dystrophic Mice
1995
Myc-Nick: A Cytoplasmic Cleavage Product of Myc that Promotes α-Tubulin Acetylation and Cell Differentiation
2010
Stem cells, ageing and the quest for immortality
2006 StandoutNature
Expression of three calpain isoform genes in human skeletal muscles
1998
Calpains: Intact and active?
1997
Autolysis, Ca2+ Requirement, and Heterodimer Stability in m-Calpain
1997
Intracellular Proteinases of Invertebrates: Calcium-Dependent and Proteasome/Ubiquitin-Dependent Systems
1998
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
2002 StandoutNature
Generation, Control, and Processing of Cellular Calcium Signals
2001
Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction – effects of AT1 and AT2 receptor antagonists and ACE inhibitor
2001
The calpain family and human disease
2001
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Purification of Active Calpain by Affinity Chromatography on an Immobilized Peptide Inhibitor
1996
Functional Properties of Recombinant Calpain I and of Mutants Lacking Domains III and IV of the Catalytic Subunit
1997
Characterization of Monoclonal Antibodies to Calpain 3 and Protein Expression in Muscle from Patients with Limb-Girdle Muscular Dystrophy Type 2A
1998
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
Exercise-induced muscle injury: A calpain hypothesis
1998
Structure and Physiology of Calpain, an Enigmatic Protease
1998
The Transcription Factor Mef2 Links the Drosophila Core Clock to Fas2, Neuronal Morphology, and Circadian Behavior
2013 StandoutNobel
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
1998 Standout
Chapter 11 Proteinase families and their inhibitors
2001
Independent inactivation of MPF and cytostatic factor (Mos) upon fertilization of Xenopus eggs
1991 StandoutNatureNobel
The Major Calpain Isozymes Are Long-lived Proteins
1996
Characterization of a distinct set of intra-axonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability
1996
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Specific proteolysis of the c-mos proto-oncogene product by calpain on fertilization of Xenopus eggs
1989 Nature
A Controlled Trial of High-Dose Intravenous Immune Globulin Infusions as Treatment for Dermatomyositis
1993 Standout
Dissociation and Aggregation of Calpain in the Presence of Calcium
2001
Proteolytic Regulation of the Zinc Finger Transcription Factor YY1, a Repressor of Muscle-restricted Gene Expression
1998
Calcineurin Activity Is Required for the Initiation of Skeletal Muscle Differentiation
2000
Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis
1986 StandoutScience
The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic Cells
2001 StandoutNobel
Comparison of low- and high-calcium-requiring forms of the calcium-activated protease with their autocatalytic breakdown products
1982
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
2010 StandoutNobel
FHL3 binds MyoD and negatively regulates myotube formation
2007
Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle.
1995 StandoutNobel
Review
1995
Disruption of the Murine Calpain Small Subunit Gene, Capn4: Calpain Is Essential for Embryonic Development but Not for Cell Growth and Division
2000
Purification and characterization of a calcium-dependent protease from rat liver
1983
Purification of the Ca2+-dependent proteinase inhibitor from bovine cardiac muscle and its interaction with the millimolar Ca2+-dependent proteinase.
1987
Subcellular localization of bovine heart calcium-dependent protease inhibitor
1985
Purification and characterization of a protein inhibitor of calcium-dependent proteases from rat liver
1984
Properties of erythrocyte membrane binding and autolytic activation of calcium-activated neutral protease
1989
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
Amino-terminal conserved region in proteinase inhibitor domain of calpastatin potentiates its calpain inhibitory activity by interacting with calmodulin-like domain of the proteinase.
1994
Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum.
1985 StandoutNobel
Reversible interaction between Ca2+‐activated neutral protease (CANP) and its endogenous inhibitor
1985
A stoichiometric complex of neurexins and dystroglycan in brain
2001 StandoutNobel
The Calpain System
2003 Standout
Calcium Ion in Skeletal Muscle: Its Crucial Role for Muscle Function, Plasticity, and Disease
2000
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes.
1995 StandoutNobel
A factor X-activating cysteine protease from malignant tissue.
1981
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Eph/ephrin interactions modulate muscle satellite cell motility and patterning
2011
Role of Ca2+ and Ca2+-activated protease in myoblast fusion
1986
Differential degradation of myofibrillar proteins by four calcium‐dependent proteinase activities from lobster muscle
1993
Affinity labelling of the Ca2+-activated neutral proteinase (calpain) in intact human platelets
1993
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Analysis of calcium-dependent interaction between amino-terminal conserved region of calpastatin functional domain and calmodulin-like domain of mu-calpain large subunit.
1994
Cell locomotion and focal adhesions are regulated by substrate flexibility
1997 Standout
Complement activation in muscle fiber necrosis: Demonstration of the membrane attack complex of complement in necrotic fibers
1982
Calcium-activated neutral protease inhibitor from rabbit erythrocytes lacks the N-terminal region of the liver inhibitor but retains three inhibitory units
1987
Molt cycle-associated changes in calcium-dependent proteinase activity that degrades actin and myosin in crustacean muscle
1982
LRP-1 Silencing Prevents Malignant Cell Invasion despite Increased Pericellular Proteolytic Activities
2008
Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment
2007 StandoutNobel
Analysis of structure-function relationship of pig calpastatin by expression of mutated cDNAs in Escherichia coli.
1988
Purification of a high-molecular-weight inhibitor of the calcium-activated proteinase
1985
Studies of the alpha-actinin/actin interaction in the Z-disk by using calpain
1991
The role of proteolysis in cell cycle progression in Schizosaccharomyces pombe.
1996 StandoutNobel
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
Cellular and Molecular Regulation of Muscle Regeneration
2004 Standout
Effect of Ca2+ on binding of the calpains to calpastatin
1989
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Stable expression of calpain 3 from a muscle transgene in vivo : Immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation
2002
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
All four repeating domains of the endogenous inhibitor for calcium-dependent protease independently retain inhibitory activity. Expression of the cDNA fragments in Escherichia coli.
1988
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein?
1984 Nature
Qualitative analysis of skeletal myosin as substrate of Ca2+-activated neutral protease: comparison of filamentous and soluble, native, and L2-deficient myosin.
1984
How do intracellular proteolytic systems change with age
1998
Studies of the active site of m-calpain and the interaction with calpastatin
1993
Works of Patrick Cottin being referenced
Ca2+‐dependent association between a Ca2+‐activated neutral proteinase (CaANP) and its specific inhibitor
1981
Involvement of myogenic regulator factors during fusion in the cell line C2C12
2002
Calpain and myogenesis: development of a convenient cell culture model
2002
Evidence for a Ca2+‐independent association between calpain II and phospholipid vesicles
1988
Potential m-Calpain Substrates during Myoblast Fusion
1999
Free calcium and calpain I activity
1991
Ca2+-dependent proteinases (calpains) and muscle cell differentiation
1994
Degradation of protein kinase Mα by μ-calpain in a μ-calpain-protein kinase Cα complex
1999
Myoblast Fusion Requires Fibronectin Degradation by Exteriorized m-Calpain
1997
Quantitative measurement of calpain I and II mRNAs in differentiating rat muscle cells using a competitive polymerase chain reaction method
1993
Evidence for fibronectin degradation by calpain II
1993
Autolysis of µ- and m-Calpain from Bovine Skeletal Muscle
2001
Involvement of micro-calpain (CAPN 1) in muscle cell differentiation
2003
Myoblast migration is regulated by calpain through its involvement in cell attachment and cytoskeletal organization
2003
Myoblast migration is prevented by a calpain‐dependent accumulation of MARCKS
2003
MAP Kinase-dependent Degradation of p27Kip1 by Calpains in Choroidal Melanoma Cells
2003
In vitro digestion of dystrophin by calcium-dependent proteases, calpains I and II
1992
Myristoylated alanine-rich C kinase substrate (MARCKS) is involved in myoblast fusion through its regulation by protein kinase Cα and calpain proteolytic cleavage
2004
Rat myoblast fusion requires exteriorized m-calpain activity.
1994
Characterization and purification of a Ca2+ ion-activated neutral proteinase inhibitor in rabbit skeletal muscle
1981
Purification and some physico-chemical and enzymic properties of a calcium ion-activated neutral proteinase from rabbit skeletal muscle
1979
Evidence for non-competitive inhibition between two calcium-dependent activated neutral proteinases and their specific inhibitor
1983
Calcium-ion-activated neutral proteinase of muscle is found in other tissues
1981
An antisense oligodeoxyribonucleotide to m-calpain mRNA inhibits myoblast fusion
1995
Evidence for implication of muscle-specific calpain (p94) in myofibrillar integrity.
1996