Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages
2005 StandoutNobel
Regulation of Blood and Lymphatic Vascular Separation by Signaling Proteins SLP-76 and Syk
2003 Science
Lipid Rafts As a Membrane-Organizing Principle
2009 StandoutScience
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Positive and Negative Regulation of FcεRI-Mediated Signaling by the Adaptor Protein LAB/NTAL
2004
The Cell Biology of Phagocytosis
2011
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production
2005
Arrestin 3 Mediates Endocytosis of CCR7 following Ligation of CCL19 but Not CCL21
2008
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
The complexities of skeletal biology
2003 StandoutNature
T cell receptor signalling in the control of regulatory T cell differentiation and function
2016
Dectin-1: a signalling non-TLR pattern-recognition receptor
2005
ERM proteins regulate cytoskeleton relaxation promoting T cell–APC conjugation
2004
Molecular regulation of mast cell activation
2006
Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins
2005
A Requirement for Phosphatidylinositol 3-Kinase in Pseudopod Extension
1999
Defective degranulation and calcium mobilization of bone-marrow derived mast cells from Xid and Btk-deficient mice
1998
Function of Rho family proteins in actin dynamics during phagocytosis and engulfment
2000
The role of PI3K in immune cells
2003
Toll-like Receptors and Innate Immunity
2001
The αβ versus γδ T-cell lineage choice
1998
Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor
2003
Transducing signals from antigen receptors to nuclear factor κB
2003
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
2011
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Pattern Recognition Receptors and Inflammation
2010 Standout
CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells
2009
Actin Cytoskeleton Reorganization by Syk Regulates Fcγ Receptor Responsiveness by Increasing Its Lateral Mobility and Clustering
2014
Vav-family proteins in T-cell signalling
2005
Regulated portals of entry into the cell
2003 StandoutNature
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
2009 StandoutNature
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
2002
Vav1 Transduces T Cell Receptor Signals to the Activation of the Ras/ERK Pathway via LAT, Sos, and RasGRP1
2004
Antigen-Receptor Signaling to Nuclear Factor κB
2006
Myosin II‐dependent exclusion of CD45 from the site of Fcγ receptor activation during phagocytosis
2012
Regulation of peripheral B cell maturation
2006
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Lymphangiogenesis in development and human disease
2005 StandoutNature
Rho GTPases in cell biology
2002 StandoutNature
T cell antigen receptor signal transduction
1997
Control of pre-T cell proliferation and differentiation by the GTPase Rac-1
2000
Phosphoinositide 3-kinase in immunological systems
2002
Regulation of phospholipase C γ isoforms in haematopoietic cells
2001
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line
2002
Phosphoinositide 3-Kinase and p72 Noncovalently Associate with the Low Affinity Fcγ Receptor on Human Platelets through an Immunoreceptor Tyrosine-based Activation Motif
1996
The development of allergic inflammation
2008 StandoutNature
The Atg18-Atg2 Complex Is Recruited to Autophagic Membranes via Phosphatidylinositol 3-Phosphate and Exerts an Essential Function
2008 StandoutNobel
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
Phagocytosis and innate immunity
2002
Eukaryotic Chemotaxis: Distinctions between Directional Sensing and Polarization
2003
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster
2006
ZAP-70 Is Essential for the T Cell Antigen Receptor-induced Plasma Membrane Targeting of SOS and Vav in T Cells
2000
Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation
2008
Osteoclast differentiation and activation
2003 StandoutNature
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Signals involved in thymocyte positive and negative selection
1999
A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes
1997
Requirement for NF-κB in osteoclast and B-cell development
1997
Metabolism, migration and memory in cytotoxic T cells
2011
Structurally Distinct Phosphatases CD45 and CD148 Both Regulate B Cell and Macrophage Immunoreceptor Signaling
2008
T-cell-receptor- and B-cell-receptor-mediated activation of NF-κB in lymphocytes
2004
New developments in FcεRI regulation, function and inhibition
2007
LAT Is Essential for FcεRI-Mediated Mast Cell Activation
2000
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Three-dimensional segregation of supramolecular activation clusters in T cells
1998 StandoutNature
HS1 Functions as an Essential Actin-Regulatory Adaptor Protein at the Immune Synapse
2006
Deciphering the pathway from the TCR to NF-κB
2006
Src-family kinases: rheostats of immune cell signaling
2004
Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse
2005
GRAIL
2003
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Pathogen Recognition and Innate Immunity
2006 Standout
Integrated signalling pathways for mast-cell activation
2006 Standout
Inflammasomes in health and disease
2012 StandoutNature
Vav Is Required for Cyclin D2 Induction and Proliferation of Mouse B Lymphocytes Activated via the Antigen Receptor
2001
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
1999 StandoutNature
Signaling pathways in phagocytosis
1999
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
1997
A Critical Role for Syk Protein Tyrosine Kinase in Fc Receptor-Mediated Antigen Presentation and Induction of Dendritic Cell Maturation
2003
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
2008 StandoutNobel
Translocation of PKCθ in T cells is mediated by a nonconventional, PI3-K– and Vav-dependent pathway, but does not absolutely require phospholipase C
2002
PDK1 Nucleates T Cell Receptor-Induced Signaling Complex for NF-κB Activation
2005 Science
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells
2012 StandoutNobel
WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell mov
2001
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
Mixed-Lineage Kinase 3 Delivers CD3/CD28-Derived Signals into the IκB Kinase Complex
2000
Bone Resorption by Osteoclasts
2000 StandoutScience
Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease
2000 StandoutScience
Syk Activation Initiates Downstream Signaling Events During Human Polymorphonuclear Leukocyte Phagocytosis
1999 StandoutNobel
The Four Distal Tyrosines Are Required for LAT-dependent Signaling in FcεRI-mediated Mast Cell Activation
2003
Vav1 Regulates Phospholipase Cγ Activation and Calcium Responses in Mast Cells
2001
Focal Exocytosis of Vamp3-Containing Vesicles at Sites of Phagosome Formation
2000
Restricted Accumulation of Phosphatidylinositol 3-Kinase Products in a Plasmalemmal Subdomain during Fcγ Receptor-Mediated Phagocytosis
2001
MECHANISMS OF PHAGOCYTOSIS IN MACROPHAGES
1999 Standout
Analysis of Thymocyte Development Reveals That the Gtpase Rhoa Is a Positive Regulator of T Cell Receptor Responses in Vivo
2001
Sialylated multivalent antigens engage CD22in transand inhibit B cell activation
2009
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
IgG Fc Receptors
2001
SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.
1999
Redundant and Opposing Functions of Two Tyrosine Kinases, Btk and Lyn, in Mast Cell Activation
2000
Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells
2003
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Deficiency of Small Gtpase Rac2 Affects T Cell Activation
2001
Regulation of phagocytosis by Rho GTPases
2015
The tandem Src homology 2 domain of the Syk kinase: A molecular device that adapts to interphosphotyrosine distances
2003
Early Steps of Clathrin-Mediated Endocytosis Involved in Phagosomal Escape of Fcγ Receptor-Targeted Adenovirus
2005
Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis
2000
Real-Time Manipulation of T Cell-Dendritic Cell Interactions In Vivo Reveals the Importance of Prolonged Contacts for CD4+ T Cell Activation
2007
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
Dysregulated FcεRI Signaling and Altered Fyn and SHIP Activities in Lyn-Deficient Mast Cells
2004
The Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils
1998
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Rate and extent of phagocytosis in macrophages lacking vamp3
2002
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
A contractile activity that closes phagosomes in macrophages
1999
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection
2009
Natural and Engineered Disorders of Lymphocyte Development
1998 Science
ZAP-70 and SLP-76 Regulate Protein Kinase C-θ and NF-κB Activation in Response to Engagement of CD3 and CD28
2001
Works of Patrick Costello being referenced
Raf Signaling but not the ERK Effector SAP-1 Is Required for Regulatory T Cell Development
2007
Loss of Rho function in the thymus is accompanied by the development of thymic lymphoma
2000
Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse
2002
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
1995 Nature
Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice
1999
Inhibition of β2 Integrin Receptor and Syk Kinase Signaling in Monocytes by the Src Family Kinase Fgr
2001
The SH3 domain of Bruton's tyrosine kinase displays altered ligand binding properties when auto‐phosphorylatedin vitro
1999
The Gtpase Rho Controls a P53-Dependent Survival Checkpoint during Thymopoiesis
2000
The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-κB pathways
1999
Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells.
1996
A Critical Role for Syk in Signal Transduction and Phagocytosis Mediated by Fcγ Receptors on Macrophages
1997