Patrick C. Hoffmann

A cryo-ET survey of microtubules and intracellular compartments in mammalian axons

UCSF ChimeraX: Tools for structure building and analysis

Regulation of microRNA function in animals

Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes

TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins

A-to-I editing of coding and non-coding RNAs by ADARs

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Base editing: precision chemistry on the genome and transcriptome of living cells

Site‐Directed RNA Editing with Antagomir Deaminases — A Tool to Study Protein and RNA Function

Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells

Search-and-replace genome editing without double-strand breaks or donor DNA

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Adeno-associated virus vector as a platform for gene therapy delivery

Mitochondria as multifaceted regulators of cell death

Editing the Genome Without Double-Stranded DNA Breaks

Translation dynamics in human cells visualized at high resolution reveal cancer drug action

CRISPR-Cas guides the future of genetic engineering

CRISPR-Cas in Streptococcus pyogenes

Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis

Structures of the eukaryotic ribosome and its translational states in situ

Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids

Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans