Standout Papers
Citation Impact
Citing Papers
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Functional specialization of β-arrestin interactions revealed by proteomic analysis
2007 StandoutNobel
Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial
2013
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Phosphorylation of MYPT1 by protein kinase C attenuates interaction with PP1 catalytic subunit and the 20 kDa light chain of myosin
2000
Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 ‘Knockout’
2003
Emotion Enhances Learning via Norepinephrine Regulation of AMPA-Receptor Trafficking
2007
Gangliosides: Treatment Avenues in Neurodegenerative Disease
2019
Structural basis of long-term potentiation in single dendritic spines
2004 StandoutNature
Chemical Technologies for Probing Glycans
2006 StandoutNobel
Oncogenic kinase signalling
2001 StandoutNature
Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking
2013 StandoutNobel
Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases
2003
Inducible and Reversible Enhancement of Learning, Memory, and Long-Term Potentiation by Genetic Inhibition of Calcineurin
2001 Nobel
G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction
2002
SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning
2010 StandoutNobel
Bcr–Abl variants: biological and clinical aspects
2002
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
BCR/ABL induces multiple abnormalities of cytoskeletal function.
1997
Genomewide suggestive linkage of opioid dependence to chromosome 14q
2007
Paradoxical Striatal Cellular Signaling Responses to Psychostimulants in Hyperactive Mice
2006
Multiple Interactions within the AKAP220 Signaling Complex Contribute to Protein Phosphatase 1 Regulation
2001
NMDA receptor hypofunction model of schizophrenia
1999
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Inositol Pentakis- and Hexakisphosphate Metabolism Adds Versatility to the Actions of Inositol Polyphosphates Novel Effects on Ion Channels and Protein Traffic
1996
The Akt–GSK-3 signaling cascade in the actions of dopamine
2007
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Crohn's disease
2016 Standout
Review article: remission rates achievable by current therapies for inflammatory bowel disease
2011
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Preventing Postoperative Recurrence in Crohn’s Disease: What Does the Future Hold?
2013
Current evidence supporting mucosal healing and deep remission as important treatment goals for inflammatory bowel disease
2016
Relaxation of a transfer RNA specificity by removal of modified nucleotides
1990 Nature
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Structure–stability–function relationships of dendritic spines
2003
The Hypothalamic Neuropeptide Melanin-Concentrating Hormone Acts in the Nucleus Accumbens to Modulate Feeding Behavior and Forced-Swim Performance
2005
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
Environmental enrichment reduces the mnemonic and neural benefits of estrogen
2004
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Preprodynorphin-, preproenkephalin-, preprotachykinin A- and preprotachykinin B-immunoreactive neurons in the accumbens nucleus and olfactory tubercle: double-immunofluorescence analysis
2002
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The molecular basis of CaMKII function in synaptic and behavioural memory
2002
Molecular genetics, natural history and the demise of childhood leukaemia
1999
Regulation of Synaptic Strength by Protein Phosphatase 1
2001
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Modulation of Amyloid Precursor Protein Metabolism by X11α/Mint-1
2000
Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase
1991 StandoutNatureNobel
First-line therapy in adult Crohn's disease: who should receive anti-TNF agents?
2013
The molecular neurobiology of depression
2008 StandoutNature
Transgenic Mice Overexpressing Glycogen Synthase Kinase 3β: A Putative Model of Hyperactivity and Mania
2006
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Cardiac excitation–contraction coupling
2002 StandoutNature
In Vitro Analysis of Mutations Causing Myoclonus Epilepsy with Ragged-Red Fibers in the Mitochondrial tRNALys Gene: Two Genotypes Produce Similar Phenotypes
1995
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
2003
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
2008 StandoutNobel
Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation
1999
Involvement of the Extracellular Signal-Regulated Kinase Cascade for Cocaine-Rewarding Properties
2000
Protein phosphatase 1 – targeted in many directions
2002
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
The Mitochondrial Genome of the Hemichordate Balanoglossus carnosus and the Evolution of Deuterostome Mitochondria
1998 StandoutNobel
Physiologic importance of protein phosphatase inhibitors
1998
The Postsynaptic Architecture of Excitatory Synapses: A More Quantitative View
2007
Cloning and identification of MYPT3: a prenylatable myosin targetting subunit of protein phosphatase 1
2001
Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes
2006 StandoutNobel
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate
2000
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Systematic review with meta‐analysis: mucosal healing is associated with improved long‐term outcomes in Crohn's disease
2015
The Neurobiology of Slow Synaptic Transmission
2001 Science
β-Arrestins and Cell Signaling
2007 StandoutNobel
Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids
2000 StandoutNobel
Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca 2+ /calmodulin-dependent pathway
2006 StandoutNobel
A default mode of brain function
2001 Standout
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
Localization of a high-affinity inositol 1,4,5-trisphosphate/inositol 1,4,5,6-tetrakisphosphate binding domain to the pleckstrin homology module of a new 130 kDa protein: characterization of the determinants of structural specificity
1996
Phosphodiesterase 4D is required for β 2 adrenoceptor subtype-specific signaling in cardiac myocytes
2005 StandoutNobel
Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron
2012 StandoutNobel
JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines
2015
The molecular biology of chronic myeloid leukemia
2000
1997 StandoutNobel
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters
2008 StandoutNobel
Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1.
2000
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Phosphorylation-Dependent Regulation of Ryanodine Receptors
2001
Transfer RNA editing in land snail mitochondria.
1995 StandoutNobel
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
2001 StandoutScienceNobel
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
Regulation of Neurotransmitter Release by Synapsin III
2002
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning
2008 StandoutNobel
Editing of Transfer RNAs in Acanthamoeba castellanii Mitochondria
1993 Science
Protein fucosylation regulates synapsin Ia/Ib expression and neuronal morphology in primary hippocampal neurons
2005
A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission
2003 StandoutNobel
What Is the Role of β-Adrenergic Signaling in Heart Failure?
2003
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis
2003 StandoutNobel
Works of Patrick B. Allen being referenced
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of theBCRgene
1989
Is myosin phosphatase regulated in vivo by inhibitor‐1? Evidence from inhibitor‐1 knockout mice
2001
Does Anti-TNF Therapy Reduce the Requirement for Surgery in Ulcerative Colitis? A Systematic Review
2011
Isolation and Characterization of PNUTS, a Putative Protein Phosphatase 1 Nuclear Targeting Subunit
1998
Philadelphia chromosome-positive leukaemia: the translocated genes and their gene products
1992
Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: Localization to and within dendritic spines
2003
Moving towards disease modification in inflammatory bowel disease therapy
2013
Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex
2001 Nobel
The DARPP-32/protein phosphatase-1 cascade: a model for signal integration1Published on the World Wide Web on 22 January 1998.1
1998
Beyond the Dopamine Receptor
1999
Inhibitor-1 Is Not Required for the Activation of Glycogen Synthase by Insulin in Skeletal Muscle
1999
Practical application of anti-TNF therapy for luminal Crohnʼs disease
2011
Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP–32 and spinophilin
1999
Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity
2006
Mucosal Healing in Crohnʼs Disease
2012
Phosphorylation of Spinophilin Modulates Its Interaction with Actin Filaments
2003
The Rho-Specific GEF Lfc Interacts with Neurabin and Spinophilin to Regulate Dendritic Spine Morphology
2005
Dopamine D1 Receptor‐Induced Gene Transcription Is Modulated by DARPP‐32
2000
Novel Target Sites for Estrogen Action in the Dorsal Hippocampus: An Examination of Synaptic Proteins1
2001
Protein phosphatase 1 regulation by inhibitors and targeting subunits
2001
Characterization of the Neuronal Targeting Protein Spinophilin and Its Interactions with Protein Phosphatase-1
1999
Review article: the natural history of postoperative C rohn's disease recurrence
2012
Type 1 Phosphatase, a Negative Regulator of Cardiac Function
2002
Protein Phosphatase-1 Regulation in the Induction of Long-Term Potentiation: Heterogeneous Molecular Mechanisms
2000
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
1997
A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells.
1994
Regulation of Neurabin I Interaction with Protein Phosphatase 1 by Phosphorylation
1999
Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts
1993
Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice
2004
Regulation of Phosphorylation of the GluR1 AMPA Receptor in the Neostriatum by Dopamine and PsychostimulantsIn Vivo
2000
Spinophilin regulates the formation and function of dendritic spines
2000