Citation Impact
Citing Papers
On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Lessons from application of the UNRES force field to predictions of structures of CASP10 targets
2013
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
2012 StandoutNobel
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Rapid protein fold determination using unassigned NMR data
2003 StandoutNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Protein homology model refinement by large-scale energy optimization
2018 StandoutNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Protein Conformational Switches: From Nature to Design
2012
Conversion of monomeric protein L to an obligate dimer by computational protein design
2001 StandoutNobel
A Thermodynamic Scale for the .beta.-Sheet Forming Tendencies of the Amino Acids
1994
Slow formation of aggregation‐resistant β‐sheet folding intermediates
2009
A short linear peptide that folds into a native stable β-hairpin in aqueous solution
1994
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Engineering proteinase K using machine learning and synthetic genes
2007
Critical role of beta-hairpin formation in protein G folding.
2000 StandoutNobel
Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design
2005
Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain
1998
Kinetics versus Thermodynamics in Protein Folding
1994 StandoutNobel
Assessing the accuracy of physical models used in protein-folding simulations: quantitative evidence from long molecular dynamics simulations
2014
Potent slow-binding inhibition of cathepsin B by its propeptide
1992
Loop length, intramolecular diffusion and protein folding
1997
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Catalysis of a protein folding reaction: Thermodynamic and kinetic analysis of subtilisin BPN' interactions with its propeptide fragment
1993
Different folding transition states may result in the same native structure
1996
Strategy for the Directed Evolution of a Peptide Ligase
1996 StandoutNobel
The role of pro regions in protein folding
1993 StandoutNobel
The barriers in protein folding
1994
Topogenic signals in integral membrane proteins
1988
Fast and Slow Intermediate Accumulation and the Initial Barrier Mechanism in Protein Folding
2002
Protein folding in the landscape perspective: Chevron plots and non-arrhenius kinetics
1998
Conformational analysis of peptides corresponding to all the secondary structure elements of protein L B1 domain: Secondary structure propensities are not conserved in proteins with the same fold
1997
Aromatic rescue of glycine in β sheets
1998
Directed evolution of enzyme catalysts
1997 StandoutNobel
Molecular dynamics simulations of peptides and proteins with a continuum electrostatic model based on screened Coulomb potentials
2003
Neuroligin 1: A splice site-specific ligand for β-neurexins
1995 StandoutNobel
Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes
2007
Conserved residues and the mechanism of protein folding
1996 Nature
Favourable native-like helical local interactions can accelerate protein folding
1997
Extremely rapid protein folding in the absence of intermediates
1995
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Transition state in the folding of α‐lactalbumin probed by the 6‐120 disulfide bond
1998
Direct evidence for a two‐state protein unfolding transition from hydrogen‐deuterium exchange, mass spectrometry, and NMR
1996 StandoutNobel
Structured States of Disordered Proteins from Genomic Sequences
2016
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Engineering Protein Switches: Sensors, Regulators, and Spare Parts for Biology and Biotechnology
2011
Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy
1998
Molecular collapse: The rate-limiting step in two-state cytochrome c folding
1996
The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP.
1999
A molecular dynamics simulation study of segment B1 of protein G
1997
High-throughput screening for enhanced protein stability
2006
Directed evolution study of temperature adaptation in a psychrophilic enzyme 1 1Edited by J. A. Wells
2000 StandoutNobel
Contact order, transition state placement and the refolding rates of single domain proteins 1 1Edited by P. E. Wright
1998 StandoutNobel
Complementation of peptide fragments of the single domain protein chymotrypsin inhibitor 2
1997
Folding of subtilisin BPN': characterization of a folding intermediate
1993
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Directed evolution of enzyme stability
2005
Design of protein conformational switches
2006
The origins of asymmetry in the folding transition states of protein L and protein G
2002
Obligatory steps in protein folding and the conformational diversity of the transition state
1998
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn
1999 StandoutNobel
Measurement of the β-sheet-forming propensities of amino acids
1994 Nature
Optimizing pH Response of Affinity between Protein G and IgG Fc
2009
Kinetic role of early intermediates in protein folding
1997
The sequences of small proteins are not extensively optimized for rapid folding by natural selection
1998 StandoutNobel
Exploring the nature of the translocon-assisted protein insertion
2012 StandoutNobel
Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability
1997 StandoutNobel
Computational method to reduce the search space for directed protein evolution
2001 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
2005 StandoutScience
Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures
1999 StandoutNobel
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Conjugation of Luminescent Quantum Dots with Antibodies Using an Engineered Adaptor Protein To Provide New Reagents for Fluoroimmunoassays
2002
Submillisecond folding of monomeric lambda repressor.
1995
Transient aggregates in protein folding are easily mistaken for folding intermediates
1997
Fragment Reconstitution of a Small Protein: Disulfide Mutant of a Short C-Terminal Fragment Derived from Streptococcal Protein G
1999
Structure of the transition state for folding of the 129 aa protein CheY resembles that of a smaller protein, CI-2
1996
Directed evolution of a thermostable esterase
1998 StandoutNobel
Two Crystal Structures of the B1 Immunoglobulin-Binding Domain of Streptococcal Protein G and Comparison with NMR
1994
Long-range order in the src SH3 folding transition state
2000 StandoutNobel
Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications.
1995
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 å resolution 1 1Edited by I. A. Wilson
1998
A family of thermostable fungal cellulases created by structure-guided recombination
2009 StandoutNobel
A Novel, Highly Stable Fold of the Immunoglobulin Binding Domain of Streptococcal Protein G
1991 Science
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Quantum Mechanical Continuum Solvation Models
2005 Standout
Protein topology and stability define the space of allowed sequences
2002 StandoutNobel
Enzyme engineering reaches the boiling point
1998 StandoutNobel
Computational design of a pH-sensitive IgG binding protein
2013 StandoutNobel
Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G
1994
Clustering of low-energy conformations near the native structures of small proteins
1998 StandoutNobel
Limited internal friction in the rate-limiting step of a two-state protein folding reaction
1998 StandoutNobel
Barriers to protein folding: formation of buried polar interactions is a slow step in acquisition of structure.
1996
Works of Patrick Alexander being referenced
NMR structures of two designed proteins with high sequence identity but different fold and function
2008
A minimal sequence code for switching protein structure and function
2009
The design and characterization of two proteins with 88% sequence identity but different structure and function
2007
Mutational Tipping Points for Switching Protein Folds and Functions
2012
Directed Evolution of a Subtilisin with Calcium-Independent Stability
1995
An engineered disulfide cross-link accelerates the refolding rate of calcium-free subtilisin by 850-fold
1993
Structural Basis of Thermostability
2002
Kinetic analysis of folding and unfolding the 56 amino acid IgG-binding domain of streptococcal protein G
1992
Energetics of folding subtilisin BPN'
1992
Mechanism of the Kinetically-Controlled Folding Reaction of Subtilisin
2006
Gene for an immunoglobulin-binding protein from a group G streptococcus
1986
Structure and Dynamics of an Acid-Denatured Protein G Mutant
2000
Solution NMR Structures of IgG Binding Domains with Artificially Evolved High Levels of Sequence Identity but Different Folds,
2005
Directed Evolution of Highly Homologous Proteins with Different Folds by Phage Display: Implications for the Protein Folding Code
2005
Directed Coevolution of Stability and Catalytic Activity in Calcium-free Subtilisin
2005