Citation Impact
Citing Papers
Selective BRAFV600E Inhibition Enhances T-Cell Recognition of Melanoma without Affecting Lymphocyte Function
2010
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Bridging the Gap between Preclinical and Clinical Studies Using Pharmacokinetic–Pharmacodynamic Modeling: An Analysis of GDC-0973, a MEK Inhibitor
2012
Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling
2011
A Genome-Scale RNA Interference Screen Implicates NF1 Loss in Resistance to RAF Inhibition
2013
Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors
2017
Effects of MAPK and PI3K Pathways on PD-L1 Expression in Melanoma
2014
Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation
2008
A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors
2014
Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer
2016
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
2016 Standout
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Vitiligo-Like Depigmentation in Patients With Stage III-IV Melanoma Receiving Immunotherapy and Its Association With Survival: A Systematic Review and Meta-Analysis
2015
Hallmarks of Cancer: The Next Generation
2011 Standout
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Trametinib (GSK1120212) in the treatment of melanoma
2013
Combined Vemurafenib and Cobimetinib in BRAF -Mutated Melanoma
2014 Standout
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
MEK in cancer and cancer therapy
2013
A view on drug resistance in cancer
2019 StandoutNature
Analysis of the genome to personalize therapy for melanoma
2010
High prevalence of MAP2K1 mutations in variant and IGHV4-34–expressing hairy-cell leukemias
2013
Tumor adaptation and resistance to RAF inhibitors
2013
Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense
2008
Chronic inflammation in the etiology of disease across the life span
2019 Standout
NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
2014
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Lessons from the Cancer Genome
2013
Inhibition of both BRAF and MEK in BRAFV600E mutant melanoma restores compromised dendritic cell (DC) function while having differential direct effects on DC properties
2013
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
2006 Standout
Cancer drug resistance: an evolving paradigm
2013 Standout
A computationally engineered RAS rheostat reveals RAS–ERK signaling dynamics
2016 StandoutNobel
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Radiomics: Images Are More than Pictures, They Are Data
2015 Standout
Shared and Distinct Functions of Type I and Type III Interferons
2019
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
The Cancer Genome Atlas Pan-Cancer analysis project
2013 Standout
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
Myeloid-derived suppressor cells as regulators of the immune system
2009 Standout
Targeting Mutant BRAF in Melanoma
2012
Engineering interferons and interleukins for cancer immunotherapy
2022
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Autophagy in the Pathogenesis of Disease
2008 Standout
Translation of new cancer treatments from pet dogs to humans
2008 Standout
Induction of Neutrophil Extracellular DNA Lattices by Placental Microparticles and IL-8 and Their Presence in Preeclampsia
2005
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Phosphorylation of BRAF by AMPK Impairs BRAF-KSR1 Association and Cell Proliferation
2013
Common pitfalls in preclinical cancer target validation
2017 StandoutNobel
Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps
2009
Emerging Biological Principles of Metastasis
2017 Standout
A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma
2013
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types
2013
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
2008 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The PI3K Pathway in Human Disease
2017 Standout
Drugging the undruggable RAS: Mission Possible?
2014
Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1
2012
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
MEK Inhibition in the Treatment of Advanced Melanoma
2013
Neutrophil recruitment and function in health and inflammation
2013 Standout
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Extracellular DNA traps promote thrombosis
2010 Standout
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Systematic identification of signaling pathways with potential to confer anticancer drug resistance
2014
Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy
2017
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity
2008
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade
2018 Standout
Immunoglobulin G Antibody-Mediated Enhancement of Measles Virus Infection Can Bypass the Protective Antiviral Immune Response
2006
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates
2009
Circumventing Cancer Drug Resistance in the Era of Personalized Medicine
2012
Works of Patrick A. Oberholzer being referenced
RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors
2011
Induction of Genes Mediating Interferon-dependent Extracellular Trap Formation during Neutrophil Differentiation
2004
Intratumoral Injection of DNA Encoding Human Interleukin 12 into Patients with Metastatic Melanoma: Clinical Efficacy
2005
Oncolytic measles virus in cutaneous T-cell lymphomas mounts antitumor immune responses in vivo and targets interferon-resistant tumor cells
2005
MEK1 mutations confer resistance to MEK and B-RAF inhibition
2009