Pasquale Simonelli

The 2.6 Angstrom Crystal Structure of a Human A _2A Adenosine Receptor Bound to an Antagonist

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

Novel Alexa Fluor-488 labeled antagonist of the A2A adenosine receptor: Application to a fluorescence polarization-based receptor binding assay

Adenosine receptors as therapeutic targets

The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: From pathology to imaging

Introduction of Fluorine and Fluorine‐Containing Functional Groups

The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development

Novel investigational adenosine A_2Areceptor antagonists for Parkinson's disease

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update

Introduction to Adenosine Receptors as Therapeutic Targets

Physiology and Pathophysiology of Purinergic Neurotransmission

Mitochondrial Membrane Permeabilization in Cell Death

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

In vivo PET imaging of neuroinflammation in Alzheimer’s disease

Recent developments in adenosine receptor ligands and their potential as novel drugs

Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum

Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?

Early and protective microglial activation in Alzheimer’s disease: a prospective study using¹⁸F-DPA-714 PET imaging

Alzheimer's disease

Adenosine Receptor Antagonists:  Translating Medicinal Chemistry and Pharmacology into Clinical Utility

Synthesis and Evaluation of No-Carrier-Added 8-Cyclopentyl-3-(3-[¹⁸F]fluoropropyl)-1-propylxanthine ([¹⁸F]CPFPX):  A Potent and Selective A₁-Adenosine Receptor Antagonist for in Vivo Imaging

Inflammation as a central mechanism in Alzheimer's disease

Chromone: A Valid Scaffold in Medicinal Chemistry

The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors

Radiohalogen incorporation into organic systems

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

Receptors for Purines and Pyrimidines

Microglial M1/M2 polarization and metabolic states

Up-Regulation of the Peripheral Benzodiazepine Receptor during Human Colorectal Carcinogenesis and Tumor Spread

Synthesis, labeling, and biological evaluation of halogenated 2-quinolinecarboxamides as potential radioligands for the visualization of peripheral benzodiazepine receptors

In vivo imaging of adenosine A2A receptors in rat and primate brain using [11C]SCH442416

Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo pet imaging of neurodegeneration

Radiosynthesis of [123I]βCIT, a selective ligand for the study of the dopaminergic and serotoninergic systems in human brain

Design, Radiosynthesis, and Biodistribution of a New Potent and Selective Ligand for in Vivo Imaging of the Adenosine A_2A Receptor System Using Positron Emission Tomography