Citation Impact
Citing Papers
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Role of ETS Transcription Factors in the Hypoxia-Inducible Factor-2 Target Gene Selection
2006
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
The Tumor Suppressor Activity of the Lysyl Oxidase Propeptide Reverses the Invasive Phenotype of Her-2/neu–Driven Breast Cancer
2007
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Use of an in Vitro Model of Tissue-Engineered Skin to Investigate the Mechanism of Skin Graft Contraction
2006
Lysyl Oxidase Is Required for Vascular and Diaphragmatic Development in Mice
2003
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Idiopathic pulmonary fibrosis
2017 Standout
Cellular Fibronectin Binds to Lysyl Oxidase with High Affinity and Is Critical for Its Proteolytic Activation
2005
Cell–matrix adhesion
2007
A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
2013 Standout
Liver fibrosis
2005 Standout
Lethal cutis laxa with contractural arachnodactyly, overgrowth and soft tissue bleeding due to a novel homozygous fibulin‐4 gene mutation
2009
Lysyl oxidase in development, aging and pathologies of the skin
2005
A Fluorometric Assay for Detection of Lysyl Oxidase Enzyme Activity in Biological Samples
2002
Portal tract fibrogenesis in the liver
2004
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Hypoxia/reoxygenation: A dynamic regulator of lysyl oxidase‐facilitated breast cancer migration
2007
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Dynamic interplay between the collagen scaffold and tumor evolution
2010
Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
2009 Standout
Transcriptional control of cancer metastasis
2013
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
2007
Mechanisms and treatment of cardiovascular disease in Williams-Beuren syndrome
2008
Lysyl oxidases: A novel multifunctional amine oxidase family
2001
Regulation of elastin promoter by lysyl oxidase and growth factors: Cross control of lysyl oxidase on TGF-β1 effects
2007
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF- in mammary epithelial cells via a MMP-dependent mechanism
2008
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Lysyl oxidase: an oxidative enzyme and effector of cell function
2006
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Molecular and cellular mechanisms of liver fibrosis and its regression
2020
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Williams–Beuren Syndrome
2010 Standout
Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis
2016
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Hypoxia signalling in cancer and approaches to enforce tumour regression
2006 Nature
Selective upregulation and amplification of the lysyl oxidase like‐4 (LOXL4) gene in head and neck squamous cell carcinoma
2007
Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor Progression
2010
Emerging Biological Principles of Metastasis
2017 Standout
Arabidopsis SGS2 and SGS3 Genes Are Required for Posttranscriptional Gene Silencing and Natural Virus Resistance
2000 Standout
Lysyl oxidase like 4, a novel target gene of TGF-β1 signaling, can negatively regulate TGF-β1-induced cell motility in PLC/PRF/5 hepatoma cells
2008
The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Cas in Breast Cancer Cells
2008
Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2
2005
The Lysyl Oxidase Inhibitor, β-Aminopropionitrile, Diminishes the Metastatic Colonization Potential of Circulating Breast Cancer Cells
2009
Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell
2002 Standout
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
The basics of epithelial-mesenchymal transition
2009 Standout
The RNA-dependent RNA polymerase of cowpea is not involved in cowpea mosaic virus RNA replication: Immunological evidence
1984
A molecular role for lysyl oxidase‐like 2 enzyme in Snail regulation and tumor progression
2005
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Conserved elements in the 3′ untranslated region of flavivirus RNAs and potential cyclization sequences
1987 StandoutNobel
Systemic Effects on Bone Healing of a New Hyaluronic Acid-Like Bacterial Exopolysaccharide
2003
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Peribiliary myofibroblasts in biliary type liver fibrosis
2002
The LOXL2 Gene Encodes a New Lysyl Oxidase-like Protein and Is Expressed at High Levels in Reproductive Tissues
1999
Heterotypic Signaling between Epithelial Tumor Cells and Fibroblasts in Carcinoma Formation
2001
Prostate cancer invasion and metastasis: insights from mining genomic data
2013
A Dialogue between the Hypoxia-Inducible Factor and the Tumor Microenvironment
2008
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Differential expression of the LOX family genes in human colorectal adenocarcinomas
2009
Inactivation of the Lysyl Oxidase Gene Lox Leads to Aortic Aneurysms, Cardiovascular Dysfunction, and Perinatal Death in Mice
2002
Nucleotide Sequence of Yellow Fever Virus: Implications for Flavivirus Gene Expression and Evolution
1985 StandoutScienceNobel
Structural disorder and dynamics of elastinThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.
2010
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Structure and Spectroscopy of Copper−Dioxygen Complexes
2004 Standout
Lysine post-translational modifications of collagen
2012
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy
2012
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Replication Strategies of the Single Stranded RNA Viruses of Eukaryotes
1983
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Elastic fibres
2002 Standout
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Gene expression profiling identifies clinically relevant subtypes of prostate cancer
2004
Paradoxical roles for lysyl oxidases in cancer—A prospect
2007
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Lysyl Oxidase Mediates Hypoxic Control of Metastasis
2006
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Current status of novel antifibrotic therapies in patients with chronic liver disease
2011
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Works of Pascal Sommer being referenced
The HIF-1–Inducible Lysyl Oxidase Activates HIF-1 via the Akt Pathway in a Positive Regulation Loop and Synergizes with HIF-1 in Promoting Tumor Cell Growth
2011
The upregulation of lysyl oxidase in oral submucous fibrosis and squamous cell carcinoma
1999
The Propeptide Domain of Lysyl Oxidase Induces Phenotypic Reversion of Ras-transformed Cells
2004
Replication of alfalfa mosaic virus RNA: Evidence for a soluble replicase in healthy and infected tobacco leaves
1980
The mouse lysyl oxidase-like 2 gene (mLOXL2) maps to chromosome 14 and is highly expressed in skin, lung and thymus
2000
A p.C217R Mutation in Fibulin-5 from Cutis Laxa Patients Is Associated with Incomplete Extracellular Matrix Formation in a Skin Equivalent Model
2008
Down-regulation of Lysyl Oxidase-induced Tumorigenic Transformation in NRK-49F Cells Characterized by Constitutive Activation of Ras Proto-oncogene
2001
LOXL as a target to increase the elastin content in adult skin: a dill extract induces the LOXL gene expression
2006
Lysyl Oxidase-Like and Lysyl Oxidase Are Present in the Dermis and Epidermis of a Skin Equivalent and in Human Skin and Are Associated to Elastic Fibers
2004
Autocrine Growth Factor Regulation of Lysyl Oxidase Expression in Transformed Fibroblasts
2003
The Pro-regions of Lysyl Oxidase and Lysyl Oxidase-like 1 Are Required for Deposition onto Elastic Fibers
2005
Lysyl Oxidase-like Protein from Bovine Aorta
2001
Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat.
1997
The Lysyl Oxidase LOX Is Absent in Basal and Squamous Cell Carcinomas and Its Knockdown Induces an Invading Phenotype in a Skin Equivalent Model
2006
Functional analysis of the lysyl oxidase promoter in myofibroblast-like clones of 3T6 fibroblast
1997
A molecular role for lysyl oxidase in breast cancer invasion.
2002
Selective expression of lysyl oxidase (LOX) in the stromal reactions of broncho-pulmonary carcinomas.
2000
Expression Analysis of Recombinant Lysyl Oxidase (LOX) in Myofibroblastlike Cells
2002
Lysyl oxidase gene expression in the stromal reaction to in situ and invasive ductal breast carcinoma.
1997
Lysyl Oxidase cDNA of Myofibroblast from Mouse Fibrotic Liver
1994
Expression analysis of recombinant lysyl oxidase (LOX) in myofibroblastlike cells.
2002