Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
Human Immunodeficiency Virus Type 2 (HIV-2)/HIV-1 Envelope Chimeras Detect High Titers of Broadly Reactive HIV-1 V3-Specific Antibodies in Human Plasma
2008
Mechanisms of Viral Membrane Fusion and Its Inhibition
2001
Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
2010
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation
2001 StandoutNobel
Identification of a major co-receptor for primary isolates of HIV-1
1996 StandoutNature
The role of CD4 in HIV binding and entry
1993
Electron Tomography of the Contact between T Cells and SIV/HIV-1: Implications for Viral Entry
2007
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Scorpion-Toxin Mimics of CD4 in Complex with Human Immunodeficiency Virus gp120
2005
Distribution and three-dimensional structure of AIDS virus envelope spikes
2006 Nature
Conformational constraints imposed on a pan-neutralizing HIV-1 antibody epitope result in increased antigenicity but not neutralizing response
2004
Broad HIV-1 neutralization mediated by CD4-binding site antibodies
2007
Antibodies, viruses and vaccines
2002
Peptide ligation and its application to protein engineering
1999
Progressive epitope-blocked panning of a phage library for isolation of human RSV antibodies
2002
B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
2012
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1998 StandoutNature
Structure of an unliganded simian immunodeficiency virus gp120 core
2005 Nature
The past, present and future of neutralizing antibodies for hepatitis C virus
2014
SNAREpins: Minimal Machinery for Membrane Fusion
1998 StandoutNobel
Core Structure of gp41 from the HIV Envelope Glycoprotein
1997 Standout
Principles for designing ideal protein structures
2012 StandoutNatureNobel
A Strategy for O-Glycoproteomics of Enveloped Viruses—the O-Glycoproteome of Herpes Simplex Virus Type 1
2015
Complete mapping of viral escape from neutralizing antibodies
2017
Partial Enzymatic Deglycosylation Preserves the Structure of Cleaved Recombinant HIV-1 Envelope Glycoprotein Trimers
2012
Antibody neutralization and escape by HIV-1
2003 StandoutNature
Structural Details of HIV-1 Recognition by the Broadly Neutralizing Monoclonal Antibody 2F5: Epitope Conformation, Antigen-Recognition Loop Mobility, and Anion-Binding Site
2008
Membrane Fusion
2003 StandoutNobel
The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development
2014
Super-resolution biomolecular crystallography with low-resolution data
2010 StandoutNatureNobel
Challenges for structure-based HIV vaccine design
2009
A potential pitfall in 18 O‐based N‐linked glycosylation site mapping
2007
A Blueprint for HIV Vaccine Discovery
2012
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants
2006
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Immunopathogenesis and immunotherapy in AIDS virus infections
2003
The Role of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins in Virus Infection
1995
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Mutations That Destabilize the gp41 Core Are Determinants for Stabilizing the Simian Immunodeficiency Virus-CPmac Envelope Glycoprotein Complex
2002
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
2009
Antibodies to conserved epitopes of the HIV-1 envelope in sera from long-term non-progressors: prevalence and association with neutralizing activity
2006
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Structural definition of a conserved neutralization epitope on HIV-1 gp120
2007 Nature
Proline-catalysed Mannich reactions of acetaldehyde
2008 StandoutNatureNobel
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
HIV fusion and its inhibition
2001
A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antibodies in Humans
2013 StandoutNobel
Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
2011 StandoutNobel
Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
1997 StandoutNatureNobel
Cancer-related inflammation
2008 StandoutNature
HIV-1: Cofactors provide the entry keys
1996
Structural Analysis of the Epitope of the Anti-HIV Antibody 2F5 Sheds Light into Its Mechanism of Neutralization and HIV Fusion
2003
The Coinhibitory Receptor CTLA-4 Controls B Cell Responses by Modulating T Follicular Helper, T Follicular Regulatory, and T Regulatory Cells
2014
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Structure and Mechanistic Analysis of the Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5 in Complex with Its gp41 Epitope
2004
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
The Mannose-Dependent Epitope for Neutralizing Antibody 2G12 on Human Immunodeficiency Virus Type 1 Glycoprotein gp120
2002
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Propensity for a leucine zipper-like domain of human immunodeficiency virus type 1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex.
1994
Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies
2004
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity
2005
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein
2005
Induction of Mucosal and Systemic Neutralizing Antibodies against Human Immunodeficiency Virus Type 1 (HIV-1) by Oral Immunization with Bovine Papillomavirus-HIV-1 gp41 Chimeric Virus-Like Particles
2004
Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables
2009
Viral persistencein vivothrough selection of neutralizing antibody-escape variants
2000
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Synthesis of Native Proteins by Chemical Ligation
2000
HIV-1 entry inhibitors: Evading the issue
1999
Characterization of Infectious Retroviral Pseudotype Particles Bearing Hepatitis C Virus Glycoproteins
2004 StandoutNobel
Oligomeric Modeling and Electrostatic Analysis of the gp120 Envelope Glycoprotein of Human Immunodeficiency Virus
2000
Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design
2011 Science
CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1
1997
CD4-Induced Conformational Changes in the Human Immunodeficiency Virus Type 1 gp120 Glycoprotein: Consequences for Virus Entry and Neutralization
1998
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1α (SDF-1α) and SDF-1β are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
1998 StandoutNobel
The Membrane-Proximal Tryptophan-Rich Region of the HIV Glycoprotein, gp41, Forms a Well-Defined Helix in Dodecylphosphocholine Micelles,
2001
Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals
1997
Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals
2008
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Structural modulations of the envelope gp120 glycoprotein of human immunodeficiency virus type 1 upon oligomerization and differential V3 loop epitope exposure of isolates displaying distinct tropism upon virion-soluble receptor binding
1995
Redox-Triggered Infection by Disulfide-Shackled Human Immunodeficiency Virus Type 1 Pseudovirions
2003
Dissecting the Neutralizing Antibody Specificities of Broadly Neutralizing Sera from Human Immunodeficiency Virus Type 1-Infected Donors
2007
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine
2018 StandoutNobel
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Broad Neutralization of Human Immunodeficiency Virus Type 1 (HIV-1) Elicited from Human Rhinoviruses That Display the HIV-1 gp41 ELDKWA Epitope
2009
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120
2012
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
HIV VACCINES
2005
Structural insights into key sites of vulnerability on HIV ‐1 Env and influenza HA
2012
A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
2008
Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions
2003
Ultrastructural and Biophysical Characterization of Hepatitis C Virus Particles Produced in Cell Culture
2010
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Factors involved in entry of the human immunodeficiency virus type 1 into permissive cells: lack of evidence of a role for CD26
1994
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Identification of CXCR4 Domains That Support Coreceptor and Chemokine Receptor Functions
1999
The Long Third Complementarity-Determining Region of the Heavy Chain Is Important in the Activity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5
2004
Increased Neutralization Sensitivity of CD4-Independent Human Immunodeficiency Virus Variants
2001
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Prospects for the Future
2002 StandoutScienceNobel
Chemical Glycoproteomics
2016 StandoutNobel
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120
2002
Works of Pascal Poignard being referenced
Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIV Ba-L
2009
Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
2011
Human and simian immunodeficiency viruses: virus-receptor interactions
1993
Antibodies in human infectious disease
2000
Neutralizing Antibodies Have Limited Effects on the Control of Established HIV-1 Infection In Vivo
1999
Epitope exposure on functional, oligomeric HIV-1 gp41 molecules
1995
A Limited Number of Antibody Specificities Mediate Broad and Potent Serum Neutralization in Selected HIV-1 Infected Individuals
2010
Antibody neutralization of HIV-1
1996
Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses
2013
Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers
2009
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
2009
PGV04, an HIV-1 gp120 CD4 Binding Site Antibody, Is Broad and Potent in Neutralization but Does Not Induce Conformational Changes Characteristic of CD4
2012
Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1
2003
Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV
2014
Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation.
1996
Anti-HIV B Cell Lines as Candidate Vaccine Biosensors
2012
Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120
2002
Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding
1993
Heterogeneity of Envelope Molecules Expressed on Primary Human Immunodeficiency Virus Type 1 Particles as Probed by the Binding of Neutralizing and Nonneutralizing Antibodies
2002
Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses
2012 Science
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
2012
Human Antibody Responses to Mature and Immature Forms of Viral Envelope in Respiratory Syncytial Virus Infection: Significance for Subunit Vaccines
1999
Highly Potent RANTES Analogues either Prevent CCR5-Using Human Immunodeficiency Virus Type 1 Infection In Vivo or Rapidly Select for CXCR4-Using Variants
1999
GP120: Biologic Aspects of Structural Features
2001
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
2010
Neutralization Synergy of Human Immunodeficiency Virus Type 1 Primary Isolates by Cocktails of Broadly Neutralizing Antibodies
2001