Pascal Notin

Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs

Rapid and automated design of two-component protein nanomaterials using ProteinMPNN

Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function

Computational design of soluble and functional membrane protein analogues

Multistate and functional protein design using RoseTTAFold sequence space diffusion

Opportunities and challenges in design and optimization of protein function

ProGen2: Exploring the boundaries of protein language models

Machine learning-guided co-optimization of fitness and diversity facilitates combinatorial library design in enzyme engineering

Opportunities and Challenges for Machine Learning-Assisted Enzyme Engineering

Accurate proteome-wide missense variant effect prediction with AlphaMissense

Machine learning for functional protein design

Disease variant prediction with deep generative models of evolutionary data