Citation Impact
Citing Papers
Drosophila melanogaster Is a Genetically Tractable Model Host for Mycobacterium marinum
2003
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Genome-Wide RNAi Screen for Host Factors Required for Intracellular Bacterial Infection
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TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
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Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae
2002
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
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Genetic Basis of Natural Variation in D. melanogaster Antibacterial Immunity
2004 Science
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
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Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 StandoutScience
The Homeobox Gene Caudal Regulates Constitutive Local Expression of Antimicrobial Peptide Genes in Drosophila Epithelia
2003
Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease
2002 StandoutScienceNobel
The two origins of hemocytes in Drosophila
2003
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Transport of dsRNA into Cells by the Transmembrane Protein SID-1
2003 Science
Circulating blood cells function as a surveillance system for damaged tissue in Drosophila larvae
2008
A Store-operated Calcium Channel in Drosophila S2 Cells
2004
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
Extensive Diversity of Ig-Superfamily Proteins in the Immune System of Insects
2005 Science
Pirk Is a Negative Regulator of the Drosophila Imd Pathway
2008
c-Jun Is Essential for Organization of the Epidermal Leading Edge
2003
A Ubiquitin-Proteasome Pathway Represses the Drosophila Immune Deficiency Signaling Cascade
2002
Isolation and Characterization of Hemolymph Clotting Factors in Drosophila melanogaster by a Pullout Method
2004
Nitric oxide contributes to induction of innate immune responses to gram-negative bacteria in Drosophila
2003
The Drosophila Peptidoglycan Recognition Protein PGRP-LF Blocks PGRP-LC and IMD/JNK Pathway Activation
2008
IRF-7 is the master regulator of type-I interferon-dependent immune responses
2005 StandoutNature
The lesswright mutation activates Rel-related proteins, leading to overproduction of larval hemocytes in Drosophila melanogaster
2005
Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster
2003
Host-pathogen interactions in drosophila: new tricks from an old friend
2006
Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the <I>Drosophila</I> innate immune system
2005
Systematic variation in gene expression patterns in human cancer cell lines
2000 Standout
Peptidoglycan recognition proteins: pleiotropic sensors and effectors of antimicrobial defences
2007
Toll receptors and pathogen resistance
2003
Inflammation and metabolic disorders
2006 StandoutNature
The Drosophila immune system detects bacteria through specific peptidoglycan recognition
2003
NMR Structure of Citrobacter freundii AmpD, Comparison with Bacteriophage T7 Lysozyme and Homology with PGRP Domains
2003
The roles of JAK/STAT signaling in Drosophila immune responses
2004
Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll
2008
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria
2004 StandoutNobel
Peptidoglycan recognition proteins: on and off switches for innate immunity
2004
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Wound repair and regeneration
2008 StandoutNature
A Vast Repertoire of Dscam Binding Specificities Arises from Modular Interactions of Variable Ig Domains
2007 StandoutNobel
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Signaling and membrane dynamics during phagocytosis: many roads lead to the phagos(R)ome
2004
Thicker Than Blood
2003
A systems biology analysis of the Drosophila phagosome
2006 Nature
Sequential Activation of Signaling Pathways during Innate Immune Responses in Drosophila
2002
Sensing and signaling during infection in Drosophila
2004 StandoutNobel
A Scavenger Function for a DrosophilaPeptidoglycan Recognition Protein
2003
Stochastic yet biased expression of multiple Dscam splice variants by individual cells
2004
Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila
2013 Standout
The Drosophila Immune Defense against Gram-Negative Infection Requires the Death Protein dFADD
2002 StandoutNobel
Functional Dissection of an Innate Immune Response by a Genome-Wide RNAi Screen
2004
Toll-like receptors in innate immunity
2004 Standout
Blood Dendritic Cells Interact with Splenic Marginal Zone B Cells to Initiate T-Independent Immune Responses
2002
Human Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L-alanine Amidase
2003
Wound healing recapitulates morphogenesis in Drosophila embryos
2002
The Toll and Imd pathways are the major regulators of the immune response in Drosophila
2002
In Vivo RNA Interference Analysis Reveals an Unexpected Role for GNBP1 in the Defense against Gram-positive Bacterial Infection in Drosophila Adults
2004
Structural Basis for Preferential Recognition of Diaminopimelic Acid-type Peptidoglycan by a Subset of Peptidoglycan Recognition Proteins
2006
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Culture of Drosophila S2 cells and their use for RNAi-mediated loss-of-function studies and immunofluorescence microscopy
2008
Secreted Bacterial Effectors and Host-Produced Eiger/TNF Drive Death in a Salmonella-Infected Fruit Fly
2004
Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells
2004 Science
The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila
2006
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
2006 StandoutNobel
aPKCζ cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia
2007
Drosophila S2 cells: an alternative infection model for Listeria monocytogenes
2003
New insights into Drosophila larval haemocyte functions through genome-wide analysis
2005
Cellular and Genetic Analysis of Wound Healing in Drosophila Larvae
2004
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
2007 StandoutNature
PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan
2006
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 StandoutNature
Drosophila hemolectin gene is expressed in embryonic and larval hemocytes and its knock down causes bleeding defects
2003
JNK signaling and morphogenesis in Drosophila
1998
A Model of Bacterial Intestinal Infections in Drosophila melanogaster
2007 StandoutNobel
A Drosophila Pattern Recognition Receptor Contains a Peptidoglycan Docking Groove and Unusual L,D-Carboxypeptidase Activity
2004 Nobel
Inducible Expression of Double-Stranded RNA Reveals a Role for dFADD in the Regulation of the Antibacterial Response in Drosophila Adults
2002
Undertaker, a Drosophila Junctophilin, Links Draper-Mediated Phagocytosis and Calcium Homeostasis
2008
Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila
2003
Drosophila immunity: paths and patterns
2003
The immune response of Drosophila
2003 StandoutNatureNobel
Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells
2005
Characterization and Properties of a 1,3-β-d-Glucan Pattern Recognition Protein of Tenebrio molitor Larvae That Is Specifically Degraded by Serine Protease during Prophenoloxidase Activation
2003
Bacterial recognition and signalling by the Drosophila IMD pathway
2005
Drosophila melanogaster S2 cells: a model system to study Chlamydia interaction with host cells
2005
Proteomic Analysis of the Drosophila Larval Hemolymph Clot
2004
Are innate immune signaling pathways in plants and animals conserved?
2005
The immune response of Drosophila melanogaster
2004
Phagocytosis
2005
Molecular portraits of human breast tumours
2000 StandoutNature
Suppression of Drosophila cellular immunity by directed expression of the ExoS toxin GAP domain of Pseudomonas aeruginosa
2005
RNA silencing in plants
2004 StandoutNature
Signaling Role of Hemocytes in Drosophila JAK/STAT-Dependent Response to Septic Injury
2003
Blood cells of Drosophila: cell lineages and role in host defence
2003
Immune Activation of NF-κB and JNK Requires Drosophila TAK1
2003
An Immune-Responsive Serpin Regulates the Melanization Cascade in Drosophila
2002
Targeting of TAK1 by the NF-κB protein Relish regulates the JNK-mediated immune response in Drosophila
2004
The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
2007 StandoutNobel
Drosophila melanogasterAntimicrobial Defense
2003 StandoutNobel
Hemolymph coagulation and phenoloxidase in larvae
2005
DNase II deficiency impairs innate immune function in Drosophila
2006
Rudra Interrupts Receptor Signaling Complexes to Negatively Regulate the IMD Pathway
2008
Peptidoglycan recognition protein (PGRP)‐LE and PGRP‐LC act synergistically in Drosophila immunity
2004
Downregulation of the Drosophila Immune Response by Peptidoglycan-Recognition Proteins SC1 and SC2
2006 StandoutNobel
In Vivo Identification of Novel Regulators and Conserved Pathways of Phagocytosis in A. gambiae
2005
A mammalian peptidoglycan recognition protein with N-acetylmuramoyl-l-alanine amidase activity
2003
Peptidoglycan Recognition Proteins Involved in 1,3-β-D-Glucan-dependent Prophenoloxidase Activation System of Insect
2004
Nimrod, a Putative Phagocytosis Receptor with EGF Repeats in Drosophila Plasmatocytes
2007
Sensing infection in Drosophila: Toll and beyond
2004 StandoutNobel
The road to Toll
2004
Drosophila Genome-wide RNAi Screens: Are They Delivering the Promise?
2006
The Toll immune-regulated Drosophila protein Fondue is involved in hemolymph clotting and puparium formation
2006
NF- B in the Immune Response of Drosophila
2009 StandoutNobel
Inhibitor of apoptosis 2 and TAK1‐binding protein are components of the Drosophila Imd pathway
2005
Identification of Drosophila Gene Products Required for Phagocytosis of Candida albicans
2005
Pathogen Recognition and Innate Immunity
2006 Standout
Positive and negative regulation of the Drosophila immune response
2008
The plant immune system
2006 StandoutNature
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Psidin Is Required in Drosophila Blood Cells for Both Phagocytic Degradation and Immune Activation of the Fat Body
2007
The immunopathogenesis of sepsis
2002 StandoutNature
The Role of Ubiquitination in Drosophila Innate Immunity
2005
Requirements of peptidoglycan structure that allow detection by the Drosophila Toll pathway
2005
Critical evaluation of the role of the Toll‐like receptor 18‐Wheeler in the host defense of Drosophila
2002
Toll-Like Receptors
2003 Standout
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph
2004
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Rac1 signalling in theDrosophilalarval cellular immune response
2006
Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition
2005 Nobel
Drosophila RNAi Screen Reveals CD36 Family Member Required for Mycobacterial Infection
2005 Science
Transcriptional Control of Wound Repair
2007
Melanotic Mutants in Drosophila: Pathways and Phenotypes
2006
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
2000 StandoutScience
Dual Activation of the Drosophila Toll Pathway by Two Pattern Recognition Receptors
2003 StandoutScienceNobel
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila
2006
Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)–deficient mice
2003
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Peptidoglycan Molecular Requirements Allowing Detection by the Drosophila Immune Deficiency Pathway
2004
Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro
2005
Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
2005
Parallels between tissue repair and embryo morphogenesis
2004
Drosophila : The Genetics of Innate Immune Recognition and Response
2004
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Works of Pascal Manfruelli being referenced
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
2002 Nature
Drosophila Scavenger Receptor CI Is a Pattern Recognition Receptor for Bacteria
2001
Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development
2004
JNK Signaling Pathway Is Required for Efficient Wound Healing in Drosophila
2002
The tumor suppressor gene, lethal(2)giant larvae (l(2)gl), is required for cell shape change of epithelial cells during Drosophila development
1996