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Citing Papers
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Redirecting In vivo Elicited Tumor Infiltrating Macrophages and Dendritic Cells towards Tumor Rejection
2005
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Homeostatic maintenance of natural Foxp3 + CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
2005 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
IFN- γ Deficiency Exerts Gender-Specific Effects on Atherogenesis in Apolipoprotein E -/- Mice
2002
CD4+ Tregs and immune control
2004 StandoutNobel
Control ofLeishmania majorInfection in Mice Lacking TNF Receptors
1998
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells
2015
Characterization of the gene encoding the immunodominant 35 kDa protein of Mycobacterium leprae
1995
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
The Mycobacterium leprae genome: systematic sequence analysis identifies key catabolic enzymes, ATP‐dependent transport systems and a novel polA locus associated with genomic variability
1995
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
TNF‐α mediates the induction of nitric oxide synthase in macrophages but not in neutrophils in experimental cutaneous leishmaniasis
2003
Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?
2004
Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected withHelicobacter pylori
2001
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Lymphatic filariasis: parallels between the immunology of infection in humans and mice
2001
The immunology of susceptibility and resistance to Leishmania major in mice
2002 Standout
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
2003 StandoutNature
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
2002 StandoutNature
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
2000 Standout
Streptolydigin Resistance Can Be Conferred by Alterations to Either the β or β′ Subunits of Bacillus subtilis RNA Polymerase
1995
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Novel IL-12 family members shed light on the orchestration of Th1 responses
2003
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Sequencing and analysis of bacterial genomes
1996
Control of Autoimmunity by Naturally Arising Regulatory CD4+ T Cells
2003 StandoutNobel
Regulatory T cells mediate maternal tolerance to the fetus
2004 Standout
Elucidation and Chemical Modulation of Sulfolipid-1 Biosynthesis in Mycobacterium tuberculosis
2011 StandoutNobel
Natural regulatory T cells and parasites: a common quest for host homeostasis
2006
Protective Anti‐HelicobacterImmunity Is Induced with Aluminum Hydroxide or Complete Freund's Adjuvant by Systemic Immunization
2001
Effective clearance of intracellular Leishmania majorin vivo requires Pten in macrophages
2008 StandoutNobel
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae
1993
The Story So Far:Helicobacter Pyloriand Gastric Autoimmunity
2005
Requirements for Th1-dependent immunity against infection with Leishmania major
2004
Thermal ablation of tumours: biological mechanisms and advances in therapy
2014 Standout
Interplays between mouse mammary tumor virus and the cellular and humoral immune response
1999
MyD88 is essential for clearance of Leishmania major : possible role for lipophosphoglycan and Toll‐like receptor 2 signaling
2003
Natural regulatory T cells in infectious disease
2005
Arginase I induction in macrophages, triggered by Th2‐type cytokines, supports the growth of intracellular Leishmania parasites
2002
Leprosy in type I reaction and diabetes mellitus in a patient with HIV infection
2002
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function
2001 StandoutNobel
Type 1/Type 2 Immunity in Infectious Diseases
2001
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Helper T Cell Differentiation Is Controlled by the Cell Cycle
1998
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis
1993 Standout
PI3K-mediated negative feedback regulation of IL-12 production in DCs
2002
Mutations in and Monoclonal Antibody Binding to Evolutionary Hypervariable Region of Escherichia coli RNA Polymerase β′ Subunit Inhibit Transcript Cleavage and Transcript Elongation
1998
Molecular chaperones in cellular protein folding
1996 StandoutNature
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Functional B-cell response in intrahepatic lymphoid follicles in chronic hepatitis C
1999
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Comparative mycobacterial genomics
1998
In the Absence of IL-12, CD4+ T Cell Responses to Intracellular Pathogens Fail to Default to a Th2 Pattern and Are Host Protective in an IL-10−/− Setting
2002
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Re‐examination of the immunosuppressive mechanisms mediating non‐cure of Leishmania infection in mice
2004
Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology
2004
Gene Knockout Reveals a Novel Gene Cluster for the Synthesis of a Class of Cell Wall Lipids Unique to Pathogenic Mycobacteria
1997
T lymphocyte differentiation in the periphery
1998
Chapter 5 Emergence of the Th17 Pathway and Its Role in Host Defense
2008
Metagenomics and Personalized Medicine
2011
Eradication of Helicobacter pylori and Resolution of Gastritis in the Gastric Mucosa of IL‐10‐Deficient Mice
2005
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Recent advances in vaccines for leishmaniasis
2004
Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1
1997
Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells
2004
Translocation of Helicobacter pylori CagA into Gastric Epithelial Cells by Type IV Secretion
2000 StandoutScience
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
Leishmaniasis host response loci (lmr1–3) modify disease severity through a Th1/Th2-independent pathway
2003
An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease
1998
IgM anti-phenolic glycolipid I and IgG anti-10-kDa heat shock protein antibodies in sera and immune complexes isolated from leprosy patients with or without erythema nodosum leprosum and contacts
1997
The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice.
1995
Cutinase‐like proteins of Mycobacterium tuberculosis : characterization of their variable enzymatic functions and active site identification
2009
Uptake of Leishmania major Amastigotes Results in Activation and Interleukin 12 Release from Murine Skin–derived Dendritic Cells: Implications for the Initiation of Anti-Leishmania Immunity
1998
Antimicrobial agent resistance in mycobacteria: molecular genetic insights
1995
Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone
2007
Systemic Th1 Immunization of Mice againstHelicobacter pyloriInfection with CpG Oligodeoxynucleotides as Adjuvants Does Not Protect from Infection but Enhances Gastritis
2004
Life with 6000 Genes
1996 StandoutScience
Low Dose TGF-β Attenuates IL-12 Responsiveness in Murine Th Cells
1998
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Infection of C57BL/10ScCr and C57BL/10ScNCr mice withLeishmania majorreveals a role for Toll-like receptor 4 in the control of parasite replication
2004
Leishmania majorLACK Antigen Is Required for Efficient Vertebrate Parasitization
2003
Complete DNA sequence of yeast chromosome II.
1994
Advances in leishmaniasis
2005 Standout
A Natural Model ofLeishmania majorInfection Reveals a Prolonged “Silent” Phase of Parasite Amplification in the Skin Before the Onset of Lesion Formation and Immunity
2000
Homing events in the gyrA gene of some mycobacteria.
1996
Induction of Th1 cytokine responses by mycobacterial antigens in leprosy
1996
CD4+ Tregs and immune control
2004 StandoutNobel
Pathogenesis ofHelicobacter pyloriInfection
2006 Standout
Low dose TGF-beta attenuates IL-12 responsiveness in murine Th cells.
1998
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination
2002
Emergence of DiverseHelicobacterSpecies in the Pathogenesis of Gastric and Enterohepatic Diseases
2001
Alloantigen-Reactive Th1 Development in IL-12-Deficient Mice
1998
Vaccination against Helicobacter pylori - an old companion of man
2001
Molecular Mechanisms RegulatinG Th1 Immune Responses
2003
Reduction of Retrovirus-Induced Immunosuppression by In Vivo Modulation of T Cells during Acute Infection
2004 StandoutNobel
A Protective and Agonistic Function of IL-12p40 in Mycobacterial Infection
2001
Helicobacter pylori Virulence and Genetic Geography
1999 StandoutScience
Protection Against Helicobacter pylori Infection Following Immunization Is IL-12-Dependent and Mediated by Th1 Cells
2002
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Comparison of the Immune Profile of Nonhealing Cutaneous Leishmaniasis Patients with Those with Active Lesions and Those Who Have Recovered from Infection
2000
Regulatory T cells: mediating compromises between host and parasite
2002 StandoutNobel
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling
2007 StandoutNobel
Requirements for the Maintenance of Th1 Immunity In Vivo Following DNA Vaccination: A Potential Immunoregulatory Role for CD8+ T Cells
2000
Novel Program of Macrophage Gene Expression Induced by Phagocytosis ofLeishmania chagasi
2004
Cellular immune response to Mycobacterium leprae infection in human immunodeficiency virus-infected individuals
1995
THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses
1998
A Genomic Perspective on Protein Families
1997 StandoutScience
LeishmaniaPriming of Human Dendritic Cells for CD40 Ligand-Induced Interleukin-12p70 Secretion Is Strain and Species Dependent
2002
Molecular basis of rifampin resistance in Mycobacterium leprae
1993
Molecular Detection of Rifampin and Ofloxacin Resistance for Patients Who Experience Relapse of Multibacillary Leprosy
2002
Termination-altering amino acid substitutions in the beta' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation.
1994
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
The Continuing Challenges of Leprosy
2006 Standout
Impairment of Alternative Macrophage Activation Delays Cutaneous Leishmaniasis in Nonhealing BALB/c Mice
2006
Leishmania donovanip36(LACK) DNA Vaccine Is Highly Immunogenic but Not Protective against Experimental Visceral Leishmaniasis
2001
An interleukin 4 (IL-4)-independent pathway for CD4+T cell IL-4 production is revealed in IL-4 receptor-deficient mice
1997
Characterization of rifampin-resistance in pathogenic mycobacteria
1994
Continuous Activation of Autoreactive CD4+ CD25+ Regulatory T Cells in the Steady State
2003
Works of Pascal Launois being referenced
Leishmania RNA Virus Controls the Severity of Mucocutaneous Leishmaniasis
2011 Science
The IL-4 Rapidly Produced in BALB/c Mice After Infection with Leishmania major Down-Regulates IL-12 Receptor β2-Chain Expression on CD4+ T Cells Resulting in a State of Unresponsiveness to IL-12
1998
High Intralesional Interleukin‐10 Messenger RNA Expression in Localized Cutaneous Leishmaniasis Is Associated with Unresponsiveness to Treatment
2001
Genetically resistant mice lacking interleukin‐12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
1996
Immunization of BALB/c mice with Helicobacter urease B induces a T helper 2 response absent in Helicobacter infection
1998
Regulation of protective immunity against Leishmania major in mice
1998
The murine model of infection with Leishmania major and its importance for the deciphering of mechanisms underlying differences in Th cell differentiation in mice from different genetic backgrounds
2004
In susceptible mice, Leishmania major induce very rapid interleukin‐4 production by CD4+ T cells which are NK1.1−
1995
Nucleotide sequence of the first cosmid from the Mycobacterium leprae genome project: structure and function of the Rif‐Str regions
1993
Phenolic glycolipid-1 from M. leprae inhibits oxygen free radical production by human mononuclear cells
1989
IFN-γ-producing CD45RA+ CD8+ and IL-10-producing CD45RA- CD4+ T cells generated in response to LACK in naive subjects never exposed toLeishmania
2002
Interleukin (IL)–13 Is the Predominant Th2 Cytokine in Localized Cutaneous Leishmaniasis Lesions and Renders Specific CD4+T Cells Unresponsive to IL‐12
2001
The fate and persistence of Leishmania major in mice of different genetic backgrounds: an example of exploitation of the immune system by intracellular parasites
1997
In BALB/c Mice, IL-4 Production During the Initial Phase of Infection withLeishmania majorIs Necessary and Sufficient to Instruct Th2 Cell Development Resulting in Progressive Disease
2000
Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness.
1997
The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12.
1998
Leprosy reversal reaction in HIV-positive patients.
1993
Transforming Growth Factor β1 Production by CD4+CD25+Regulatory T Cells in Peripheral Blood Mononuclear Cells from Healthy Subjects Stimulated withLeishmania guyanensis
2005
Differential Production of Systemic and Intralesional Gamma Interferon and Interleukin-10 in Nodular and Ulcerative Forms of Buruli Disease
2004
Rapid IL-4 Production by Leishmania Homolog of Mammalian RACK1-Reactive CD4+ T Cells in Resistant Mice Treated Once with Anti-IL-12 or -IFN-γ Antibodies at the Onset of Infection with Leishmania major Instructs Th2 Cell Development, Resulting in Nonhealing Lesions
2002
An Immunomodulatory Function for Neutrophils During the Induction of a CD4+ Th2 Response in BALB/c Mice Infected withLeishmania major
2000
LACK-Specific CD4 + T Cells That Induce Gamma Interferon Production in Patients with Localized Cutaneous Leishmaniasis during an Early Stage of Infection
2002
T-cell-epitope mapping of the major secreted mycobacterial antigen Ag85A in tuberculosis and leprosy
1994
Immune Response to Mouse Mammary Tumor Virus in Mice Lacking the Alpha/Beta Interferon or the Gamma Interferon Receptor
1998
Altered Ligands Reveal Limited Plasticity in the T Cell Response to a Pathogenic Epitope
1999
Thymus-independent generation of NK1+ T cells in vitro from fetal liver precursors.
1997
The Early IL-4 Response toLeishmania majorand the Resulting Th2 Cell Maturation Steering Progressive Disease in BALB/c Mice Are Subject to the Control of Regulatory CD4+CD25+ T Cells
2002
T Cell Reactivity against Mycolyl Transferase Antigen 85 ofM. tuberculosisin HIV-TB Coinfected Subjects and in AIDS Patients Suffering from Tuberculosis and Nontuberculous Mycobacterial Infections
2010
Fibronectin-binding antigen 85 and the 10-kilodalton GroES-related heat shock protein are the predominant TH-1 response inducers in leprosy contacts
1995