Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
2007 StandoutNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein
2012
Structure-based inhibitors of amyloid beta core suggest a common interface with tau
2019
Roles of tau protein in health and disease
2017
Glucagon-like Peptide-1 Receptor Signaling Modulates β Cell Apoptosis
2002
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Regulation of cell death: the calcium–apoptosis link
2003 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
The role of autophagy in neurodegenerative disease
2013 Standout
Glutamate uptake
2001 Standout
Interleukin-12 and the regulation of innate resistance and adaptive immunity
2003 Standout
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
Polymorphic Structures of Alzheimer's β-Amyloid Globulomers
2011
Modulation of voltage-dependent calcium channels by neurotransmitters and neuropeptides in parasympathetic submandibular ganglion neurons
2004
Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain
2018
Cellular survival: a play in three Akts
1999 Standout
Characterization of chronic low‐level proteasome inhibition on neural homeostasis
2003
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration
2009 StandoutNobel
Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
2005
Tau in physiology and pathology
2015 Standout
Endoplasmic reticulum stress: cell life and death decisions
2005 Standout
BCL-2 family members and the mitochondria in apoptosis
1999 Standout
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Polypeptide Inhibit Interleukin-12 Transcription by Regulating Nuclear Factor κB and Ets Activation
1999
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Mitochondrial control of cell death
2000 Standout
Graphene oxide strongly inhibits amyloid beta fibrillation
2012
Biology of Incretins: GLP-1 and GIP
2007 Standout
The Role of Insulin Resistance in the Pathogenesis of Alzheimer??s Disease
2003
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
2006 Standout
Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons
2008 StandoutNobel
Selective Reconstitution and Recovery of Functional γ-Secretase Complex on Budded Baculovirus Particles
2004
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Pituitary adenylate cyclase-activating polypeptide stimulates both c-fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway
1998
Relationship between β-amyloid degradation and the 26S proteasome in neural cells
2003
Control of Neuronal Precursor Proliferation in the Cerebellum by Sonic Hedgehog
1999 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation
2006 Standout
NLRP3-dependent synaptic plasticity deficit in an Alzheimer's disease amyloidosis model in vivo
2018
No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the β-cleaved C-terminal APP fragment
2003
Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils
2010
Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species
2010
Alzheimer's Disease
2010 Standout
The Physiology of Glucagon-like Peptide 1
2007 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Molecular mechanism of Thioflavin-T binding to amyloid fibrils
2010 Standout
LRP and Alzheimer's Disease
2005
The Amyloid State of Proteins in Human Diseases
2012 Standout
Lack of Tau Proteins Rescues Neuronal Cell Death and Decreases Amyloidogenic Processing of APP in APP/PS1 Mice
2012
Oligomeric and Fibrillar Species of Amyloid-β Peptides Differentially Affect Neuronal Viability
2002 Standout
Stimuli-responsive self-assembling peptides made from antibacterial peptides
2013
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
Impaired Proteasome Function in Alzheimer's Disease
2000
Intracellular amyloid-β in Alzheimer's disease
2007 Standout
Apolipoprotein E and Low Density Lipoprotein Receptor-related Protein Facilitate Intraneuronal Aβ42 Accumulation in Amyloid Model Mice
2006
Exploring the full spectrum of macrophage activation
2008 Standout
Chapter 11 Proteinase families and their inhibitors
2001
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Homocysteic acid induces intraneuronal accumulation of neurotoxic Aβ42: Implications for the pathogenesis of Alzheimer's disease
2005
Lecanemab in Early Alzheimer’s Disease
2022 Standout
Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications
2016 Standout
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
2010 Standout
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Mechanism of Nucleated Conformational Conversion of Aβ42
2015
A Simple Detection Method for Low-Affinity Membrane Protein Interactions by Baculoviral Display
2008 StandoutNobel
Microglial activation correlates in vivo with both tau and amyloid in Alzheimer’s disease
2018
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
2003
Shining Light on the Secreted Luciferases of Marine Copepods: Current Knowledge and Applications
2018
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Intraneuronal amyloid‐β1‐42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death
2004
Comparison of Alzheimer Aβ(1–40) and Aβ(1–42) amyloid fibrils reveals similar protofilament structures
2009
Vasoactive Intestinal Peptide and Pituitary Adenylyl Cyclase-Activating Polypeptide Inhibit Tumor Necrosis Factor-α Production in Injured Spinal Cord and in Activated Microglia via a cAMP-Dependent Pathway
2000
Mitochondrial dysfunction induced by disease relevant AβPP and tau protein mutations
2006
Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Enhance IL-10 Production by Murine Macrophages: In Vitro and In Vivo Studies
1999
Glucagon-Like Peptides: Regulators of Cell Proliferation, Differentiation, and Apoptosis
2003
Ca 2+ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD
1999 Science
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
2005
Structure–neurotoxicity relationships of amyloid β-protein oligomers
2009
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
A New Structural Model of Aβ40 Fibrils
2011
Physiology of Microglia
2011 Standout
Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway.
2000
Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice
2016
Works of Pascal Kienlen‐Campard being referenced
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
2015
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo
2017
Lithium Chloride Increases the Production of Amyloid-β Peptide Independently from Its Inhibition of Glycogen Synthase Kinase 3
2005
Intracellular Amyloid-β1–42, but Not Extracellular Soluble Amyloid-β Peptides, Induces Neuronal Apoptosis
2002
The processing and biological function of the human amyloid precursor protein (APP): lessons from different cellular models
2000
Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway
1999
Failure of the interaction between presenilin 1 and the substrate of γ‐secretase to produce Aβ in insect cells
2002
A mouse model of familial amyotrophic lateral sclerosis expressing a mutant superoxide dismutase 1 shows evidence of disordered transport in the vasopressin hypothalamo‐neurohypophysial axis
1999
PACAP Type I Receptor Activation Promotes Cerebellar Neuron Survival Through the cAMP/PKA Signaling Pathway
1997
Continuous Activation of Pituitary Adenylate Cyclase‐Activating Polypeptide Receptors Elicits Antipodal Effects on Cyclic AMP and Inositol Phospholipid Signaling Pathways in CATH.a Cells: Role of Protein Synthesis and Protein Kinases
1998
Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo
2016
Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease
2016
A helix-to-coil transition at the ε-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis
2009
Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing
2015
Inhibitors of Amyloid Toxicity Based on β-sheet Packing of Aβ40 and Aβ42
2006