Citation Impact
Citing Papers
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases
2020
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Relative Unidirectional Translation in an Artificial Molecular Assembly Fueled by Light
2013 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Strong and Reversible Binding of Carbon Dioxide in a Green Metal–Organic Framework
2011 StandoutNobel
A Ribozyme for the Aldol Reaction
2005
Monofunctionalized Pillar[5]arene as a Host for Alkanediamines
2011 StandoutNobel
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Structure, folding and mechanisms of ribozymes
2005
Photoswitchable, DNA‐Binding Helical Peptides Assembled with Two Independently Designed Sequences for Photoregulation and DNA Recognition
2012
In-solution enrichment identifies peptide inhibitors of protein–protein interactions
2019
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
2013
Click chemistry reactions in medicinal chemistry: Applications of the 1,3‐dipolar cycloaddition between azides and alkynes
2007
Structure‐Based Design of Inhibitors of Protein–Protein Interactions: Mimicking Peptide Binding Epitopes
2015
Finding specific RNA motifs: Function in a zeptomole world?
2003
Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates
2004
Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization
2008
Conformational Restriction of Peptides Using Dithiol Bis-Alkylation
2016
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
Enhancements to the Rosetta Energy Function Enable Improved Identification of Small Molecules that Inhibit Protein-Protein Interactions
2015
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities
2003
Bis‐Azobenzene Crosslinkers for Photocontrol of Peptide Structure
2011
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Direct Targeting of Rab‐GTPase–Effector Interactions
2014
Nucleic Acid Based Molecular Devices
2011
The Future of Peptide‐based Drugs
2012 Standout
Peptiderive server: derive peptide inhibitors from protein–protein interactions
2016
Recognition of the DNA minor groove by pyrrole-imidazole polyamides
2003
In vitro selection of allosteric ribozymes: theory and experimental validation11Edited by R. Huber
2001
Cu-free click cycloaddition reactions in chemical biology
2010 StandoutNobel
How Chemoproteomics Can Enable Drug Discovery and Development
2012
Design of amyloidogenic peptide traps
2024 StandoutNobel
Comprehensive analysis of loops at protein-protein interfaces for macrocycle design
2014
Peptidomimetics via copper-catalyzed azide–alkyne cycloadditions
2007
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Split-protein systems: beyond binary protein–protein interactions
2011
Efficient synthesis and biological evaluation of proximicins A, B and C
2012
Acetone‐Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling
2015
The antiquity of RNA-based evolution
2002 Nature
Regulating gene expression with light-activated oligonucleotides
2006
DNA and RNA induced enantioselectivity in chemical synthesis
2006
Isolating Conformers to Assess Dynamics of Peptidic Catalysts Using Computationally Designed Macrocyclic Peptides
2021 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Orally Absorbed Cyclic Peptides
2017
DNA Origami: Scaffolds for Creating Higher Order Structures
2017
Functional Nucleic Acid Sensors
2009 Standout
A Small Aptamer with Strong and Specific Recognition of the Triphosphate of ATP
2004 StandoutNobel
DNA nanotechnology
2017
The emerging role of computational design in peptide macrocycle drug discovery
2020
Emerging Methods and Design Principles for Cell‐Penetrant Peptides
2018
Proline Editing: A General and Practical Approach to the Synthesis of Functionally and Structurally Diverse Peptides. Analysis of Steric versus Stereoelectronic Effects of 4-Substituted Prolines on Conformation within Peptides
2013
Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure
2016
Functional information and the emergence of biocomplexity
2007 StandoutNobel
Catalytic iron-carbene intermediate revealed in a cytochrome c carbene transferase
2018 StandoutNobel
Supramolecular Chirality in Self-Assembled Systems
2015 Standout
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
2015 Standout
α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells
2015
Photoinduced Electron Transfer as a Probe for the Folding Behavior of Dimethylsilylene-Spaced Alternating Donor–Acceptor Oligomers and Polymers
2013
Towards understanding cell penetration by stapled peptides
2014
Nonafluorobutanesulfonyl Azide: A Shelf‐Stable Diazo Transfer Reagent for the Synthesis of Azides from Primary Amines
2010
Analysis of Loops that Mediate Protein–Protein Interactions and Translation into Submicromolar Inhibitors
2016
Macrocyclic Control in Helix Mimetics
2019
Characterization of an RNA Active Site: Interactions between a Diels−Alderase Ribozyme and Its Substrates and Products
2002
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Self-Assembled Nanoreactors
2005
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Informational Complexity and Functional Activity of RNA Structures
2004 StandoutNobel
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
Achieving enhanced cell penetration of short conformationally constrained peptides through amphiphilicity tuning
2017
Functional Aptamers and Aptazymes in Biotechnology, Diagnostics, and Therapy
2007
Evolution of water structures in metal-organic frameworks for improved atmospheric water harvesting
2021 StandoutScienceNobel
DNA-Based Asymmetric Catalysis: Sequence-Dependent Rate Acceleration and Enantioselectivity
2008 StandoutNobel
Peptide stapling techniques based on different macrocyclisation chemistries
2014
The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design
2017 StandoutNobel
Constrained Peptides as Miniature Protein Structures
2012
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Conformational Strain of Macrocyclic Peptides in Ligand–Receptor Complexes Based on Advanced Refinement of Bound-State Conformers
2021
Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry
2008 StandoutNobel
TNA Synthesis by DNA Polymerases
2003 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Chemical Glycoproteomics
2016 StandoutNobel
Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction
2012
Works of Paramjit S. Arora being referenced
Assessment of helical interfaces in protein–protein interactions
2009
Enhanced Metabolic Stability and Protein‐Binding Properties of Artificial α Helices Derived from a Hydrogen‐Bond Surrogate: Application to Bcl‐xL
2005
Profiling small molecule inhibitors against helix–receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2
2010
Making Strides in Peptide-Based Therapeutics
2009
Contemporary strategies for the stabilization of peptides in the α-helical conformation
2008
High Specificity in Protein Recognition by Hydrogen‐Bond‐Surrogate α‐Helices: Selective Inhibition of the p53/MDM2 Complex
2010
HippDB: a database of readily targeted helical protein–protein interactions
2013
Amyloid fibrils nucleated and organized by DNA origami constructions
2014
Reversible Redox Reconfiguration of Secondary Structures in a Designed Peptide
2012
Inhibition of HIV‐1 Fusion by Hydrogen‐Bond‐Surrogate‐Based α Helices
2008
Nano-Tailoring
2004
An orthosteric inhibitor of the Ras-Sos interaction
2011
Adding Diverse Noncanonical Backbones to Rosetta: Enabling Peptidomimetic Design
2013
Plucking the high hanging fruit: A systematic approach for targeting protein–protein interactions
2012
Synthesis, incorporation efficiency, and stability of disulfide bridged functional groups at RNA 5′-ends
2000
Novel RNA catalysts for the Michael reaction
2001
Engineered protein scaffolds as leads for synthetic inhibitors of protein–protein interactions
2018
Systematic Targeting of Protein–Protein Interactions
2016
Protein–protein interactions in transcription: A fertile ground for helix mimetics
2010
Nucleation and stability of hydrogen-bond surrogate-based α-helices
2006
End-capped α-helices as modulators of protein function
2011
Structure-based inhibition of protein–protein interactions
2014
Design, synthesis and protein-targeting properties of thioether-linked hydrogen bond surrogate helices
2011
Solid-phase synthesis of short α-helices stabilized by the hydrogen bond surrogate approach
2010
Reversible α-helix formation controlled by a hydrogen bond surrogate
2011
Solid phase synthesis of hydrogen bond surrogate derived α-helices: resolving the case of a difficult amide coupling
2010
A ribozyme with michaelase activity
2003
Inhibition of HIV‐1 Fusion by Hydrogen‐Bond‐Surrogate‐Based α Helices
2008
Targeting Unoccupied Surfaces on Protein–Protein Interfaces
2017
Solid-Phase Synthesis of Hydrogen-Bond Surrogate-Derived α-Helices
2005
Nonpeptidic Foldamers from Amino Acids: Synthesis and Characterization of 1,3-Substituted Triazole Oligomers
2005
Evaluation of Biologically Relevant Short α-Helices Stabilized by a Main-Chain Hydrogen-Bond Surrogate
2006
Anatomy of β-Strands at Protein–Protein Interfaces
2014
Effects of side chains in helix nucleation differ from helix propagation
2014
A Hydrogen Bond Surrogate Approach for Stabilization of Short Peptide Sequences in α-Helical Conformation
2008
Rational Design of Topographical Helix Mimics as Potent Inhibitors of Protein–Protein Interactions
2014
Nucleation Effects in Peptide Foldamers
2012
Inhibition of Hypoxia Inducible Factor 1—Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix
2009
Hydrogen Bond Surrogate Stabilization of β-Hairpins
2018
A Highly Stable Short α-Helix Constrained by a Main-Chain Hydrogen-Bond Surrogate
2004
Protein–Protein Interactions Mediated by Helical Tertiary Structure Motifs
2015
Oligooxopiperazines as Nonpeptidic α-Helix Mimetics
2010
Assessing Helical Protein Interfaces for Inhibitor Design
2011
Design of Artificial Transcriptional Activators with Rigid Poly-l -proline Linkers
2002
An Effective Strategy for Stabilizing Minimal Coiled Coil Mimetics
2015
In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics
2014
Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling
2013
Synthesis of Hydrogen‐Bond Surrogate α‐Helices as Inhibitors of Protein‐Protein Interactions
2014
Solution- and Solid-Phase Synthesis of Triazole Oligomers That Display Protein-Like Functionality
2007
Systematic Analysis of Helical Protein Interfaces Reveals Targets for Synthetic Inhibitors
2010
Atomic Structure of a Short α-Helix Stabilized by a Main Chain Hydrogen-Bond Surrogate
2008
Enhanced Metabolic Stability and Protein‐Binding Properties of Artificial α Helices Derived from a Hydrogen‐Bond Surrogate: Application to Bcl‐xL
2005