Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules
2016 Standout
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
High‐Throughput Quality Control Assay for the Solid‐Phase Synthesis of DNA‐Encoded Libraries of Macrocycles**
2021
Property‐Driven Development of Passively Permeable Macrocyclic Scaffolds Using Heterocycles**
2022
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Engineering precision nanoparticles for drug delivery
2020 Standout
Effluxing ABC transporters in human corneal epithelium
2009
In silico ADME/T modelling for rational drug design
2015
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
High-Resolution Modeling of Transmembrane Helical Protein Structures from Distant Homologues
2014 StandoutNobel
Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1)
2008
Prediction of drug–ABC-transporter interaction — Recent advances and future challenges
2015
Statistical potential for assessment and prediction of protein structures
2006 Standout
The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli
2005 StandoutNobel
Ocular Drug Delivery
2010 Standout
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
High-Resolution Comparative Modeling with RosettaCM
2013 StandoutNobel
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
2011 Standout
The mechanisms of action of metformin
2017 Standout
The human basophil
1990
Neurovascular Alterations in Alzheimer’s Disease: Transporter Expression Profiles and CNS Drug Access
2017
Crystal structure of a eukaryotic phosphate transporter
2013 Nature
Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
2018 Standout
Principles for targeting RNA with drug-like small molecules
2018
Protein Structure Modeling with MODELLER
2008 Standout
UCSF Chimera—A visualization system for exploratory research and analysis
2004 Standout
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
Assessment of predictions submitted for the CASP7 domain prediction category
2007 StandoutNobel
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Automated comparative protein structure modeling with SWISS‐MODEL and Swiss‐PdbViewer: A historical perspective
2009 Standout
Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions
2012
New paradigms in GPCR drug discovery
2015
Coexistence of passive and carrier-mediated processes in drug transport
2010
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome
2013
Exploring the cellular accumulation of metal complexes
2009
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Protein epitope mimetic macrocycles as biopharmaceuticals
2017
Quantitative measurement of cytosolic penetration using the chloroalkane penetration assay
2020
Bridging In Vitro and In Vivo Metabolism and Transport of Faldaprevir in Human Using a Novel Cocultured Human Hepatocyte System, HepatoPac
2013
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption
2014
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
The SWISS-MODEL Repository and associated resources
2008 Standout
The status of platinum anticancer drugs in the clinic and in clinical trials
2010 Standout
ModBase, a database of annotated comparative protein structure models, and associated resources
2010
Evidence-based approach to assess passive diffusion and carrier-mediated drug transport
2012
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
Orally Absorbed Cyclic Peptides
2017
Macrocycles in Drug Discovery─Learning from the Past for the Future
2023
Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1
2015
Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability
2019
Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions
2015
The emerging role of computational design in peptide macrocycle drug discovery
2020
Emerging Methods and Design Principles for Cell‐Penetrant Peptides
2018
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations
2018
Association of Organic Cation Transporter 1 With Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study
2014
Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide
2017
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Understanding Cell Penetration of Cyclic Peptides
2019
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
2017 Standout
Extended-Connectivity Fingerprints
2010 Standout
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Non-invasive, real-time reporting drug release in vitro and in vivo
2015
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
Computational design of mixed chirality peptide macrocycles with internal symmetry
2020 StandoutNobel
Comparative Protein Structure Modeling Using MODELLER
2016 Standout
Peptidic Macrocycles - Conformational Sampling and Thermodynamic Characterization
2018
Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies
2019 StandoutNobel
Liganding Functional Tyrosine Sites on Proteins Using Sulfur–Triazole Exchange Chemistry
2020
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
RNA Display Methods for the Discovery of Bioactive Macrocycles
2018
Computational Prediction of Oral Drug Absorption Based on Absorption Rate Constants in Humans
2006
Solution Conformations Shed Light on PROTAC Cell Permeability
2020
Comparative Protein Structure Modeling Using MODELLER
2007 Standout
Improved Naïve Bayesian Modeling of Numerical Data for Absorption, Distribution, Metabolism and Excretion (ADME) Property Prediction
2006
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective
2018 Standout
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
Picomole‐Scale Synthesis and Screening of Macrocyclic Compound Libraries by Acoustic Liquid Transfer
2021
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
2017
Conformational Effects on the Passive Membrane Permeability of Synthetic Macrocycles
2022
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
2020 Standout
A Study of the Evolution of Inverted-Topology Repeats from LeuT-Fold Transporters Using AlignMe
2010
Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs
2018
CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure
2014
Mechanisms of Renal Fibrosis
2017 Standout
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Conformational Strain of Macrocyclic Peptides in Ligand–Receptor Complexes Based on Advanced Refinement of Bound-State Conformers
2021
Comparative Protein Structure Modeling Using Modeller
2006 Standout
Works of Pär Matsson being referenced
Prediction and Identification of Drug Interactions with the Human ATP-Binding Cassette Transporter Multidrug-Resistance Associated Protein 2 (MRP2; ABCC2)
2008
Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs
2009
Conditioned Media from Cultured Blood Cells of Atopic Individuals Can Induce Differentiation in the Human Basophilic Leukemia Cell Line KU812
1989
Quantifying the impact of transporters on cellular drug permeability
2015
Comparison of human solute carriers
2010
Cell permeability beyond the rule of 5
2016
A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)
2007
Structural and conformational determinants of macrocycle cell permeability
2016
The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition
2016
Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5
2018
Exploring the Role of Different Drug Transport Routes in Permeability Screening
2004
How Big Is Too Big for Cell Permeability?
2017
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
2017
Profiling of a Prescription Drug Library for Potential Renal Drug–Drug Interactions Mediated by the Organic Cation Transporter 2
2011
Structural Requirements for Drug Inhibition of the Liver Specific Human Organic Cation Transport Protein 1
2008
Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver
2013
Rapid Measurement of Intracellular Unbound Drug Concentrations
2013
Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties
2014