Citation Impact
Citing Papers
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome
1998 Standout
Inhibitory Effect of di- and Tripeptidyl Aldehydes on Calpains and Cathepsins
1990
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Structure of the Hemagglutinin Precursor Cleavage Site, a Determinant of Influenza Pathogenicity and the Origin of the Labile Conformation
1998
Synthetic Inhibitors of Elastase
1994
Novel cell-penetrating α-keto-amide calpain inhibitors as potential treatment for muscular dystrophy
2005
Calpains (intracellular calcium-activated cysteine proteinases): Structure-activity relationships and involvement in normal and abnormal cellular metabolism
1990
Host cell proteases controlling virus pathogenicity
1994
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
1996 StandoutNature
Highly sensitive peptide‐4‐methylcoumaryl‐7‐amide substrates for blood‐clotting proteases and trypsin
1988
A Strategy for Functional Proteomic Analysis of Glycosidase Activity from Cell Lysates
2004 StandoutNobel
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
2001 StandoutNature
Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases
1991
The impact of microRNAs on protein output
2008 StandoutNature
Lysosomal metabolism of glycoproteins
2005
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase
1990 StandoutNatureNobel
Membrane Fusion
2003 StandoutNobel
Essential Role for Cathepsin S in MHC Class II–Associated Invariant Chain Processing and Peptide Loading
1996
Role of Hemagglutinin Cleavage for the Pathogenicity of Influenza Virus
1999
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools
2000
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Three-Dimensional Structure of Chymotrypsin Inactivated with (2S)-N-Acetyl-L-alanyl-L-phenylalanyl .alpha.-chloroethane: Implications for the Mechanism of Inactivation of Serine Proteases by Chloroketones
1994
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
1994 Standout
Cyclin is degraded by the ubiquitin pathway
1991 StandoutNature
BI-1 Regulates an Apoptosis Pathway Linked to Endoplasmic Reticulum Stress
2004 StandoutNobel
Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gpl60
1992 Nature
Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura
1998 Standout
A novel cyclin encoded by a bcl1-linked candidate oncogene
1991 StandoutNature
Molecular cloning and expression of human hepatocyte growth factor
1989 StandoutNature
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Evolutionary families of peptidases
1993
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27
1995 StandoutScience
Bioorganometallic Chemistry of Ferrocene
2004 Standout
De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters
2014 StandoutNobel
Cysteine Proteases and Their Inhibitors
1997
Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues
2018 StandoutNobel
Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2.
1994 StandoutNobel
The selective inactivation of thiol proteasesin vitro andin vivo
1984
Cytoskeletal Protein ABP-280 Directs the Intracellular Trafficking of Furin and Modulates Proprotein Processing in the Endocytic Pathway
1997 StandoutNobel
Functional information and the emergence of biocomplexity
2007 StandoutNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Contribution of long-range electrostatic interactions to the stabilization of the catalytic transition state of the serine protease subtilisin BPN'
1993
Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages.
1995
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Mapping epitopes and antigenicity by site-directed masking
2006 StandoutNobel
The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase.
1996 StandoutNobel
Peptidyl Epoxides: Novel Selective Inactivators of Cysteine Proteases1
1996
Mass spectrometry-based proteomics
2003 StandoutNature
Inhibition of Oleamide Hydrolase Catalyzed Hydrolysis of the Endogenous Sleep-Inducing Lipid cis-9-Octadecenamide
1996
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis
1996
Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin
2000 Standout
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
The Formation of Immunogenic Major Histocompatibility Complex Class II–Peptide Ligands in Lysosomal Compartments of Dendritic Cells Is Regulated by Inflammatory Stimuli
2000 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Control of programmed cyclin destruction in a cell-free system.
1989
Neurexophilins Form a Conserved Family of Neuropeptide-Like Glycoproteins
1998 StandoutNobel
The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo.
1992 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts.
1991 StandoutNobel
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Unusual Amino Acids in Medicinal Chemistry
2016
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.
1994 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Synthesis and In Vitro Studies of Novel Pyrimidinyl Peptidomimetics as Potential Antimalarial Therapeutic Agents
2002
Recent Advances in the Baylis−Hillman Reaction and Applications
2003 Standout
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.
1992
Synthesis of peptide fluoromethyl ketones and the inhibition of human cathepsin B
1985
Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin.
1995
α-Ketocarbonyl Peptides: A General Approach to Reactive Resin-Bound Intermediates in the Synthesis of Peptide Isosteres for Protease Inhibitor Screening on Solid Support
2001 StandoutNobel
Accurate and efficient cleavage of the human insulin proreceptor by the human proprotein-processing protease furin. Characterization and kinetic parameters using the purified, secreted soluble protease expressed by a recombinant baculovirus.
1994
Tethered derivatives of d-glucose and pentacyclic triterpenes for homo/heterobivalent inhibition of glycogen phosphorylase
2010
Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.
1995 StandoutNobel
Works of P Wikström being referenced
Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones
1989
Design and evaluation of novel bivalent thrombin inhibitors based on amidinophenylalanines
1999
Active center differences between cathepsins L and B: The S1 binding region
1988
Interactions of papaya proteinase IV with inhibitors
1990
Iodination of peptidyl chloromethyl ketones for protease affinity labels
1988
The properties of peptidyl diazoethanes and chloroethanes as protease inactivators
1989
The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B
1988
An exploration of the primary specificity site of cathepsin B
1983
Synthesis and Structure−Activity Relationships of Potent Thrombin Inhibitors: Piperazides of 3-Amidinophenylalanine
1997
Evaluation of inhibitor constants and alkylation rates for a series of thrombin affinity labels
1985
The identification of active forms of cysteine proteinases in Kirsten-virus-transformed mouse fibroblasts by use of a specific radiolabelled inhibitor
1989
The synthesis of inhibitors for processing proteinases and their action on the Kex2 proteinase of yeast
1993
The synthesis of lysylfluoromethanes and their properties as inhibitors of trypsin, plasmin and cathepsin B
1987
Synthesis and properties of peptidyl derivatives of arginylfluoromethanes
1988
Inactivation of prolyl endopeptidase by a peptidylchloromethane. Kinetics of inactivation and identification of sites of modification
1991
Peptidyl fluoromethyl ketones as thiol protease inhibitors.
1986
Peptidyldiazomethanes. A novel mechanism of interaction with prolyl endopeptidase
1992