Citation Impact
Citing Papers
The human disease network
2007 Standout
Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells
2006
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
1 Developmental roles and clinical significance of Hedgehog signaling
2003
Participation of Two Members of the Very Long-chain Acyl-CoA Synthetase Family in Bile Acid Synthesis and Recycling
2002
CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless
1998 StandoutNobel
A phytol-enriched diet induces changes in fatty acid metabolism in mice both via PPARα-dependent and -independent pathways
2005
The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart
2009
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Reconsidering Movement of Eukaryotic mRNAs between Polysomes and P Bodies
2011 StandoutNobel
Thematic Review Series: Glycerolipids. Cardiolipin synthesis for the assembly of bacterial and mitochondrial membranes
2007
Genetic Ablation of Calcium-independent Phospholipase A2γ Leads to Alterations in Mitochondrial Lipid Metabolism and Function Resulting in a Deficient Mitochondrial Bioenergetic Phenotype
2007
Coupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA Decay
2011 StandoutNobel
Liver disease caused by failure to racemize trihydroxycholestanoic acid: Gene mutation and effect of bile acid therapy
2003
Premature translational termination triggers mRNA decapping
1994 Nature
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex
1998
Mitochondrial Respiratory-Chain Diseases
2003
Carnitine biosynthesis in mammals
2002
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
Early Formation of mRNP
2003 StandoutNobel
In Mouse α-Methylacyl-CoA Racemase, the Same Gene Product Is Simultaneously Located in Mitochondria and Peroxisomes
2000
Defects of cholesterol biosynthesis
2006
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Disorders of purine and pyrimidine metabolism
2005
A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
2008 Standout
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Drug-Induced Hepatotoxicity
2003 Standout
A Lethal Defect of Mitochondrial and Peroxisomal Fission
2007
Quality control of mRNA 3′-end processing is linked to the nuclear exosome
2001 StandoutNatureNobel
The enigmatic role of tafazzin in cardiolipin metabolism
2009
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
Linoleic acid supplemention of Barth syndrome fibroblasts restores cardiolipin levels: implications for treatment
2003
Structural Modifications of RNA Influence the 5′ Exoribonucleolytic Hydrolysis by XRN1 and HKE1 ofSaccharomyces cerevisiae
1997
Gout
2009 Standout
Genetic defects in the human glycome
2006
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Metabonomics: a platform for studying drug toxicity and gene function
2002 Standout
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
The Nuclear Exosome and Adenylation Regulate Posttranscriptional Tethering of Yeast GAL Genes to the Nuclear Periphery
2008 StandoutNobel
Androgen synthesis in adrenarche
2008
Omega-3 fatty acids and neuropsychiatric disorders
2005
Mitochondrial energy metabolism is markedly impaired by d-2-hydroxyglutaric acid in rat tissues
2005
Mitochondria, Oxidants, and Aging
2005 Standout
Cleft lip and palate: understanding genetic and environmental influences
2011 Standout
Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling
2016
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Inheritance and Drug Response
2003
Fish Intake, Contaminants, and Human Health
2006 Standout
5′-Exoribonuclease 1: Xrn1
2001
Evolution and diversity of copy number variation in the great ape lineage
2013
Inactivation of the Peroxisomal Multifunctional Protein-2 in Mice Impedes the Degradation of Not Only 2-Methyl-branched Fatty Acids and Bile Acid Intermediates but Also of Very Long Chain Fatty Acids
2000
The pathobiology of mucositis
2004 Standout
5′-Exonuclease-2 of Saccharomyces cerevisiae
1995
The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes
2001
Sterol carrier protein-2
2000
Regulation of cellular response to oncogenic and oxidative stress by Seladin-1
2004 Nature
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Membrane lipids: where they are and how they behave
2008 Standout
Aberrant Oxidation of the Cholesterol Side Chain in Bile Acid Synthesis of Sterol Carrier Protein-2/Sterol Carrier Protein-x Knockout Mice
1999
17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes
1999
Peroxisomal Bifunctional Protein Deficiency Revisited: Resolution of Its True Enzymatic and Molecular Basis
1999
Reactive Oxygen Species as Mediators of Cellular Senescence
2005
ABC lipid transporters: Extruders, flippases, or flopless activators?
2005
Straight-Chain Acyl-CoA Oxidase Knockout Mouse Accumulates Extremely Long Chain Fatty Acids from α-Linolenic Acid: Evidence for Runaway Carousel-Type Enzyme Kinetics in Peroxisomal β-Oxidation Diseases
2002
Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans
2015 StandoutNobel
Pyrimidine pathways in health and disease
2005
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Cardiolipin and apoptosis
2002
The Human Condition—A Molecular Approach
2014 StandoutNobel
3β-Hydroxysterol Δ7-reductase and the Smith–Lemli–Opitz syndrome
2004
Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities
2004 Standout
Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans
2001 StandoutNobel
Mutations in the Gene Encoding Peroxisomal Sterol Carrier Protein X (SCPx) Cause Leukencephalopathy with Dystonia and Motor Neuropathy
2006
HCV and the hepatic lipid pathway as a potential treatment target
2011
Fluorogenic Phospholipids as Head Group-Selective Reporters of Phospholipase A Activity
2006
The yeast UME5 gene regulates the stability of meiotic mRNAs in response to glucose.
1994
Christian Raetz: Scientist and Friend Extraordinaire
2013 StandoutNobel
PEX11 promotes peroxisome division independently of peroxisome metabolism
2002
AUUUA Is Not Sufficient To Promote Poly(A) Shortening and Degradation of an mRNA: the Functional Sequence within AU-Rich Elements May Be UUAUUUA(U/A)(U/A)
1994
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
Mutations in Translation Initiation Factors Lead to Increased Rates of Deadenylation and Decapping of mRNAs in Saccharomyces cerevisiae
1999
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.
1993
Patched1 Regulates Hedgehog Signaling at the Primary Cilium
2007 StandoutScience
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Role of calcium-independent phospholipase A 2 in the pathogenesis of Barth syndrome
2009
Steroid Hormone Biosynthesis and Actions in the Materno Fetoplacental Unit
1998
Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.
1995 StandoutNobel
PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR –ACTIVATED RECEPTOR α: An Adaptive Metabolic System
2001
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties
2007 Standout
Peroxisome Biogenesis Disorders
2003
Increased Serum Concentrations of Secondary Bile Salts during Cholate Feeding Are Due to Coprophagy. A Study with Wild-Type and Atp8b1-Deficient Mice
2006
Imaging the glycome
2008 StandoutNobel
Metabolomics for Investigating Physiological and Pathophysiological Processes
2019
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates
2012
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Role of AMACR (α-methylacyl-CoA racemase) and MFE-1 (peroxisomal multifunctional enzyme-1) in bile acid synthesis in mice
2014
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout
Works of P. Vreken being referenced
Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene.
2000
Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage
2005
L‐2‐Hydroxyglutaric aciduria and lactic acidosis
1998
Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
2000
Rapid stable isotope dilution analysis of very-long-chain fatty acids, pristanic acid and phytanic acid using gas chromatography–electron impact mass spectrometry
1998
Defective Remodeling of Cardiolipin and Phosphatidylglycerol in Barth Syndrome
2000
Rapid Diagnosis of Organic Acidemias and Fatty-acid Oxidation Defects by Quantitative Electrospray Tandem-MS Acyl-Carnitine Analysis in Plasma
2002
Dihydropyrimidinase Deficiency: Structural Organization, Chromosomal Localization, and Mutation Analysis of the Human Dihydropyrimidinase Gene
1998
Carbohydrate-deficient glycoprotein syndrome type 1a: A variant phenotype with borderline cognitive dysfunction, cerebellar hypoplasia, and coagulation disturbances
2000
Peroxisomal fatty acid α- and β-oxidation in humans: enzymology, peroxisomal metabolite transporters and peroxisomal diseases
2001
Significantly reduced docosahexaenoic and docosapentaenoic acid concentrations in erythrocyte membranes from schizophrenic patients compared with a carefully matched control group
2001
β‐Ureidopropionase deficiency: A novel inborn error of metabolism discovered using NMR spectroscopy on urine
2001
Smith-Lemli-Opitz Syndrome Is Caused by Mutations in the 7-Dehydrocholesterol Reductase Gene
1998
Nomenclature for human DPYD alleles
1998
Mutations in the 3β-Hydroxysterol Δ24-Reductase Gene Cause Desmosterolosis, an Autosomal Recessive Disorder of Cholesterol Biosynthesis
2001
Cardiolipin deficiency in x-linked cardioskeletal myopathy and neutropenia (barth syndrome, mim 302060): a study in cultured skin fibroblasts
2002
Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal α-methylacyl-CoA racemase deficiency
2001
Disorders of mitochondrial fatty acyl‐CoA β‐oxidation
1999
Rapid analysis of conjugated bile acids in plasma using electrospray tandem mass spectrometry: Application for selective screening of peroxisomal disorders
1999
Inborn errors of pyrimidine degradation: Clinical, biochemical and molecular aspects
1997
Quantitative plasma acylcarnitine analysis using electrospray tandem mass spectrometry for the diagnosis of organic acidaemias and fatty acid oxidation defects
1999
Peroxisomal d -hydroxyacyl-CoA dehydrogenase deficiency: Resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency
1998
Peroxisomal fatty acid α- and β-oxidation in humans: enzymology, peroxisomal metabolite transporters and peroxisomal diseases
2001
The Rate-Limiting Step in Yeast PGK1 mRNA Degradation Is an Endonucleolytic Cleavage in the 3′-Terminal Part of the Coding Region
1992
X‐linked cardioskeletal myopathy and neutropenia (Barth syndrome) (MIM 302060)
1999
X-linked cardioskeletal myopathy and neutropenia (Barth syndrome)—MIM 302060
1999
Late onset white matter disease in peroxisome biogenesis disorder
2001
The rate-limiting step in yeast PGK1 mRNA degradation is an endonucleolytic cleavage in the 3'-terminal part of the coding region.
1992
Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
2001