Citation Impact
Citing Papers
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
2010 StandoutScience
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression
2003
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression
2006 Standout
Antidepressant effects of ketamine in depressed patients
2000 Standout
A monomeric protein in the Golgi membrane catalyzes both N-deacetylation and N-sulfation of heparan sulfate.
1994
Histopathology of the prefrontal cortex in major depression: what does it tell us about dysfunctional monoaminergic circuits?
2000
Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments.
1994
The Biphasic Effects of Centrally and Peripherally Administered Caffeine on Ethanol-induced Motor Incoordination in Mice
1988
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Glutamate and Depression
2003
Imaging beyond the proteome
2012 StandoutNobel
Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC)
1989
A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression
2010
Purinergic mechanisms in epilepsy
1988
The N-methyl-d-aspartate antagonists phencyclidine, ketamine and dizocilpine as both behavioral and anatomical models of the dementias
1995
Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715)
1995
MK-801 and enantiomers: Potential antidepressants or false positives in classical screening models?
1993
Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain
1998
Is the forced swimming test a suitable model for revealing antidepressant activity?
1988
NMDA/glutamate mechanism of antidepressant-like action of magnesium in forced swim test in mice
2007
Dizocilpine antagonizes the effect of chronic imipramine on learned helplessness in rats
1993
Catalysis for fluorination and trifluoromethylation
2011 StandoutNature
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development
2005
Contributions of the Amygdala to Emotion Processing: From Animal Models to Human Behavior
2005 Standout
Why there are complementary learning systems in the hippocampus and neocortex: Insights from the successes and failures of connectionist models of learning and memory.
1995 Standout
Indolocarbazole natural products: occurrence, biosynthesis, and biological activity
2006
Mechanisms of Actions of Inhaled Anesthetics
2003 Standout
Effects of Moderate Alcohol Consumption on the Central Nervous System*
1998
Which molecular targets are most relevant to general anaesthesia?
1998
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
2011 StandoutNature
3 The Medicinal Chemistry of the Azido Group
1994
Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila
2008 StandoutNobel
Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation
2003 Standout
Caffeine withdrawal affects central adenosine receptors but not benzodiazepine receptors
1989
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression
1994
Honokiol and Magnolol Selectively Interact with GABA<sub>A</sub> Receptor Subtypes in vitro
2001
Electroconvulsive stimulation and synaptic plasticity in the rat
1993
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder
2008
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Neurobiology of Depression
2002 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Potential Antidepressive Properties of Amantadine, Memantine and Bifemelane
1993
Chemistry in living systems
2005 StandoutNobel
Antidepressant-like Effects of a Partial Agonist at Strychnine-insensitive Glycine Receptors and a Competitive NMDA Receptor Antagonist
1997
Major Depressive Disorder
2008 Standout
Beyond Monoamines: Glutamatergic Function in Mood Disorders
2005
Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo
2003 Standout
Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy
2013 Standout
Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes
2007 StandoutNobel
Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus
2007
The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression
2007
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
Cognitive Enhancers as Adjuncts to Psychotherapy
2004
Antidepressant-like effects of 1-aminocyclopropanecarboxylic acid and d-cycloserine in an animal model of depression
1996
The molecular neurobiology of depression
2008 StandoutNature
The Cerebellum: a Model System for Studying GABA A Receptor Diversity
1996
Long-term potentiation: What's learning got to do with it?
1997
Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects
1992 Standout
Clinically Significant Drug Interactions with Newer Antidepressants
2011
1-Aminocylopropane-1-carboxylic acid derivatives as ligands at the glycine-binding site of the N-methyl-D-aspartate receptor
1998
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
The diversity of GABAA receptors
1998
A 96-well dot-blot assay for carbohydrate sulfotransferases
2002 StandoutNobel
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory
1998 StandoutNobel
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
The role of glutamate in mood disorders: Results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects
2007
Use of calculated quantum chemical properties as surrogates for solvatochromic parameters in structure-activity relationships
1993
Roles of Nonstructural Protein nsP2 and Alpha/Beta Interferons in Determining the Outcome of Sindbis Virus Infection
2002 StandoutNobel
Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines
1980
Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands.
1993
Reactions of 1,2-Bis(1H-indol-2-yl)ethane: Formation of Indolo[2,3-c]carbazole and Cyclohept[1,2-b:5,4-b′]bisindole Derivatives
2000
Bis- and Trisindolylmethanes (BIMs and TIMs)
2009 Standout
Bioisosterism: A Rational Approach in Drug Design
1996
Memory--a Century of Consolidation
2000 StandoutScience
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Long-Term Potentiation--A Decade of Progress?
1999 StandoutScience
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Reactions of 2,3′-biindolyl: Synthesis of indolo[3,2-a]carbazoles
1999
Adenosine receptors and behavioral actions of methylxanthines.
1981
Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome
2000 StandoutScience
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Interaction of Convulsive Ligands with Benzodiazepine Receptors
1982 StandoutScience
Purinergic control of anxiety: direct behavioral evidence in the rat
1983
Purification, molecular cloning, and expression of the mammalian sigma1-binding site.
1996
Chronic caffeine consumption increases the number of brain adenosine receptors
1983
Molecular Imaging with PET
2008
Ischemic Cell Death in Brain Neurons
1999 Standout
Effect of pentoxifylline on α- and β-adrenoceptor sites in cerebral cortex, medial basal hypothalamus and pineal gland of the rat
1982
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
Basic and clinical aspects of adenosinergic neuromodulation
1985
Up-regulation of brain [3H]diazepam binding sites in chronic caffeine-treated rats
1984
Identification of Genes Involved in the Host Response to Neurovirulent Alphavirus Infection
2001
Effect of Ring Fluorination on the Pharmacology of Hallucinogenic Tryptamines
2000
Benzodiazepine antagonism by harmane and other β-carbolines in vitro and in vivo
1981
Up-regulation of brain [3H]diazepam binding sites in chronic caffeine treated rats
1986
Searching for endogenous benzodiazepine receptor ligands
1980
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Plasma adenosine levels: Measurement in humans and relationship to the anxiogenic effects of caffeine
1987
Methylxanthine discrimination in the rat: Possible benzodiazepine and adenosine mechanisms
1985
Caffeine antagonizes several central effects of diazepam
1981
Works of P. Skolnick being referenced
AHN 086: an irreversible ligand of "peripheral" benzodiazepine receptors.
1986
Electrophysiological actions of Ro5-4864 on cerebellar Purkinje neurons: evidence for "peripheral" benzodiazepine receptor-mediated depression.
1989
Ultraviolet irradiation selectively disrupts the gamma-aminobutyric acid/benzodiazepine receptor-linked chloride ionophore.
1989
Synthesis of substituted 7,12-dihydropyrido[3,2-b:5,4-b']diindoles: rigid planar benzodiazepine receptor ligands with inverse agonist/antagonist properties
1990
Inhibition of [3H]Isradipine Binding to L-Type Calcium Channels by the Optical Isomers of Isoflurane Lack of Stereospecificity
1994
Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors
1994
Predictive binding of .beta.-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach
1992
High affinity ligands for ‘diazepam-insensitive’ benzodiazepine receptors
1992
Requirements for high affinity binding of glycine analogs to the glycine site of the NMDA receptor complex
1993
Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures
1993
Drugs acting at the strychnine-insensitive glycine receptor do not induce HSP-70 protein in the cingulate cortex
1994
Functional antagonists at the NMDA receptor complex exhibit antidepressant actions
1990
Radiation inactivation reveals discrete cation binding sites that modulate dihydropyridine binding sites.
1989
ChemInform Abstract: Synthesis and Pharmacological Properties of Novel 8‐Substituted Imidazobenzodiazepines: High‐Affinity, Selective Probes for α5‐ Containing GABAA Receptors.
1996
Differential effects of compounds that act at strychnine-insensitive glycine receptors in a punishment procedure.
1994
Role of benzodiazepine receptors in seizures.
1983
Benzodiazepines are weak inhibitors of [3H]nitrobenzylthioinosine binding to adenosine uptake sites in brain
1982
Purines as endogenous ligands of the benzodiazepine receptor.
1980
Acute, stress-induced changes in the benzodiazepine/gamma-aminobutyric acid receptor complex are confined to the chloride ionophore.
1986
Putative endogenous ligands for the benzodiazepine receptor
1979
Pharmacological, electrophysiological, and neurochemical actions of the convulsant benzodiazepine Ro 5-4864 (4'-chlordiazepam).
1983
Anticonvulsant doses of inosine result in brain levels sufficient to inhibit [3H] diazepam binding
1981