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Citing Papers

Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
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A specific B2‐bradykinin receptor antagonist HOE 140 abolishes the antihypertrophic effect of ramipril
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Characterization and Regulation of Angiotensin II Receptors in Rat Adipose Tissue
1996
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics
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Repression of c- fos and c- jun gene expression is not part of AT 2 receptor coupled signal transduction
1998
Effects of angiotensin analogues and angiotensin receptor antagonists on paraventricular neurones
1992
Independent β-Arrestin2 and Gq/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor
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β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation
2002 StandoutNobel
A Hypothesis Regarding the Function of Angiotensin Peptides in the Brain
1988
Iodine-Induced Hyperthyroidism: Occurrence and Epidemiology
1998
Mapping tissue angiotensin-converting enzyme and angiotensin AT1, AT2 and AT4 receptors
1998
BRAIN ANGIOTENSIN AND CIRCULATORY CONTROL
1996
Cardiovascular end-organ damage in Ren-2 transgenic rats compared to spontaneously hypertensive rats
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2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention
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Expression of AT2 receptors in rat fetal subdermal cells
1993
Interactions of the systemic and brain renin–angiotensin systems in the control of drinking and the central mediation of pressor responses
1999
Identification of two subtypes in the rat type I angiotensin II receptor
1992
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice
1995 StandoutNatureNobel
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
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Molecular basis of human hypertension: Role of angiotensinogen
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Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Immunohistochemical evidence for the existence of angiotensin II-containing nerve terminals in the brain and spinal cord in the rat
1976
Nonpeptidic ligands for peptide and protein receptors
1999
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice
2001 StandoutNobel
The renin-angiotensin system in the rat brain
1988
Changes in expression of angiotensin receptor subtypes in the rat aorta during development
1991
Brain angiotensin receptor subtypes AT1, AT2, and AT4 and their functions
1995
Na+/h+exchange inhibitors for cardioprotective therapy: progress, problems and prospects
2002
Blockade of Angiotensin Receptors in the Anterior Hypothalamic Preoptic Area Lowers Blood Pressure in DOCA-Salt Hypertensive Rats.
2000
Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes.
1997 StandoutNobel
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Central renin injections: effects on drinking and expression of immediate early genes
1998
Angiotensin II in central nervous system physiology
1998
Expression of angiotensin II AT2 receptors in the rat skin during experimental wound healing
1992
Expression of Angiotensin Type-1 (AT1) and Type-2 (AT2) Receptor mRNAs in the Adult Rat Brain: A Functional Neuroanatomical Review
1997
Angiotensinogen gene expression in extrahepatic rat tissues: Application of a solution hybridization assay
1988
Diabetic Retinopathy
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Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
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Inability of [125I]Sar1, Ile8‐Angiotensin II to Move Between the Blood and Cerebrospinal Fluid Compartments
1988
Sialic acid-specific lectins: occurrence, specificity and function
2006
Intravenous nicorandil can preserve microvascular integrity and myocardial viability in patients with reperfused anterior wall myocardial infarction
1999
Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation
2003 Standout
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
2005 StandoutNobel
Modulation of net outward current in cultured neurons by angiotensin II: involvement of AT1 and AT2 receptors
1992
Presence of renin in primary neuronal and glial cells from rat brain
1987
An overview of inhibitors of Na+/H+ exchanger
2003
Effects of Oral Tolvaptan in Patients Hospitalized for Worsening Heart Failure<SUBTITLE>The EVEREST Outcome Trial</SUBTITLE>
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Angiotensin II depresses glutamate depolarizations and excitatory postsynaptic potentials in locus coeruleus through angiotensin II subtype 2 receptors
1994
Subclinical Thyroid Disease
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Renin-1 Is Essential for Normal Renal Juxtaglomerular Cell Granulation and Macula Densa Morphology
1997
Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury
2003
Björn Fokow Award Lecture The angiotensin type 2 receptor
1999
Physiology of Local Renin-Angiotensin Systems
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Myocardial Reperfusion Injury
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RosettaLigand Docking with Full Ligand and Receptor Flexibility
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Important roles for angiotensin III and IV in the brain renin-angiotensin system
1997
Angiotensin II Type 1–Receptor Activating Antibodies in Renal-Allograft Rejection
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The tissue renin-angiotensin systems in cardiovascular disease
1992
Flying under the radar: the new wave of BCR–ABL inhibitors
2007
Angiotensin II Stimulates the Proliferation of Osteoblast-Rich Populations of Cells from Rat Calvariae
1997
Antisense inhibition of AT1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin
1993
Reperfusion injury in humans: A review of clinical trials on reperfusion injury inhibitory strategies
2007
Homeostasis in Mice with Genetically Decreased Angiotensinogen Is Primarily by an Increased Number of Renin-producing Cells
1999 StandoutNobel
The Na+/H+exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction11This manuscript is dedicated to the memory of Karl-Ludwig Neuhaus (1944–2000).
2001
Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease
2012 Standout
Pressor and Renal Effects of Intracerebroventricularly Administered Angiotensins II and III in Rats
2000
Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor
2006
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
A decrease in angiotensin receptor binding in rat brain nuclei by antisense oligonucleotides to the angiotensin AT1 receptor
1995
Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research
2001
CAR: A virus receptor within the tight junction
2005
Molecular evidence of tissue renin-angiotensin systems: A focus on the brain
2005
Transgenic mice for studies of the renin–angiotensin system in hypertension
2004
Renin expression in the kidney and brain is reciprocally controlled by captopril
1989
Endocytosis by Random Initiation and Stabilization of Clathrin-Coated Pits
2004
Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease
2011
Brain angiotensin receptor subtypes in the control of physiological and behavioral responses
1994
Autoradiographic localization of subtypes of angiotensin II antagonist binding in the rat brain
1991
Regulatory role of brain angiotensins in the control of physiological and behavioral responses
1992
Effects of Angiotensin-Converting Enzyme Inhibition and Angiotensin II AT1 Receptor Antagonism on Cardiac Parameters in Left Ventricular Hypertrophy
1997
Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene
1990 Nature
Regulation of cell proliferation and growth by angiotensin II
1994
Converting Enzyme Inhibition Specifically Prevents the Development and Induces Regression of Cardiac Hypertrophy in Rats
1989
Review: Molecular pathogenesis of blood–brain barrier breakdown in acute brain injury
2010
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
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Brain Renin-Angiotensin System
2003
Effects of angiotensin II and vasopressin on human smooth muscle cells in vitro
1981
High blood pressure in transgenic mice carrying the rat angiotensinogen gene.
1992
Myocardial Hypertrophy, Angiotensin, and ACE Inhibitors
1993
Renin is not synthesized by cardiac and extrarenal vascular tissues. A review of experimental evidence.
1994
Prorenin, Renin, Angiotensinogen, and Angiotensin-Converting Enzyme in Normal and Failing Human Hearts
1997
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Localization of brain angiotensinogen mRNA by hybridization histochemistry
1987
Regulation of renin angiotensins by gonadotropic hormones in cultured murine Leydig tumor cells. Release of angiotensin but not renin.
1986
Isorenin, pseudorenin, cathepsin D and renin. A comparative enzymatic study of angiotensin-forming enzymes
1978
Pituitary-Dependent Renin-Like Immunoreactivity in the Rat Testis*
1983
Identification of renin and angiotensinogen messenger RNA sequences in mouse and rat brains.
1986
Angiotensin II Increases Left Ventricular Mass Without Affecting Myosin Isoform mRNAs
1996
Brain and liver angiotensinogen messenger RNA in genetic hypertensive and normotensive rats.
1991
Genetic Models of Human Vascular Disease
1995 StandoutNobel
Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.
1993 Standout
The brain renin-angiotensin system: A model for the synthesis of peptides in the brain
1978
Angiotensin Blockade Inhibits Activation of Mitogen-Activated Protein Kinases in Rat Balloon-Injured Artery
1998 StandoutNobel
Expression of Angiotensin-Converting Enzyme in Remaining Viable Myocytes of Human Ventricles After Myocardial Infarction
1996
Inhibition of the Sodium-Hydrogen Exchanger With Cariporide to Prevent Myocardial Infarction in High-Risk Ischemic Situations
2000
Induction of Renin in Medial Smooth Muscle Cells by Balloon Injury
1997
A possible role for the brain renin-angiotensin system in the regulation of LH secretion
1983
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
Signal Transduction Mechanisms Mediating the Physiological and Pathophysiological Actions of Angiotensin II in Vascular Smooth Muscle Cells
2000
Overexpression of angiotensin AT 1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block
1997 StandoutNobel
Localization of renin (EC 3.4.23) and converting enzyme (EC 3.4.15.1) in nerve endings of rat brain
1985
A Comparative Study of the Distributions of Renin and Angiotensinogen Messenger Ribonucleic Acids in Rat and Mouse Tissues*
1987
The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence.
1991
Angiotensin II Activates Mitogen-Activated Protein Kinase Via Protein Kinase C and Ras/Raf-1 Kinase in Bovine Adrenal Glomerulosa Cells
1998
Delayed Cerebroventricular Metabolism of [125I]Angiotensins in the Spontaneously Hypertensive Rat
1987
Quantitative autoradiography of angiotensin II receptors in the SHR brain
1986
Immunohistological Evidence for Renin in Human Endocrine Tissues*
1985
International Union of Pharmacology. XXIII. The Angiotensin II Receptors
2000 Standout
Local generation and release of angiotensin II in peripheral vascular tissue.
1988
Identification of renin in resident alveolar macrophages and monocytes: HPLC and immunohistochemical study
1988
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
Angiotensinogen in Cerebrospinal Fluid Corresponds Chromatographically to the γ‐Form of Plasma Angiotensinogen
1987
Pituitary‐dependent expression of the testicular angiotensin II receptor and its subtypes in rats
1998
Diverse, High-Quality Test Set for the Validation of Protein−Ligand Docking Performance
2007
Angiotensin degradation products mediate endothelium-dependent dilation of rabbit brain arterioles.
1991
Angiotensin II Type 1 Receptor Blockade Inhibits the Expression of Immediate-Early Genes and Fibronectin in Rat Injured Artery
1995
A genetically clamped renin transgene for the induction of hypertension
2002 StandoutNobel
Angiotensin II in rat brain comigrates with authentic angiotensin II in high pressure liquid chromatography.
1985
Dysfunction of central angiotensinergic aminopeptidase activity in spontaneously hypertensive rats
1985
Maximally localized Wannier functions: Theory and applications
2012 Standout
Renin and prorenin in hog brain: Ubiquitous distribution and high concentration in the pituitary and pineal
1980
Aryl-aryl cross coupling on a solid support using zinc organic reagents and palladium catalysis
1996
Evidence for the Existence of des-Asp1-Angiotensin II in Human Uterine and Adrenal Tissues*
1985
Presence of angiotensin II in neurons cultured from fetal rat brain
1980
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
Science and technology for water purification in the coming decades
2008 StandoutNature
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Antisense Inhibition of Hypertension in the Spontaneously Hypertensive Rat
1995
Angiotensin II Receptor Subtypes in the Human Renal Cortex and Renal Cell Carcinoma
1994
THE RENIN-ANGIOTENSIN SYSTEM
1994
Colloquium: Strong-field phenomena in periodic systems
2018 StandoutNobel
Imaging the glycome
2008 StandoutNobel
Genetic control of blood pressure and the angiotensinogen locus.
1995 StandoutNobel
Catalytic amination of 5-iodouracil derivatives
2001
Renin Is Expressed in Rat Macrophage/Monocyte Cells
1996
N-aryl heterocycles via coupling reactions with arylboronic acids
1999
Mechanisms and Energetics for Acid Catalyzed β-d-Glucose Conversion to 5-Hydroxymethylfurfurl
2011
Identity of angiotensinogen precursors of rat brain and liver
1984 Nature
The ovarian renin-angiotensin system: Renin-like activity and angiotensin II/III immunoreactivity in gonadotropin-stimulated and unstimulated human follicular fluid
1987
Local Angiotensin II Generation in the Rat Heart
1998
Intrathecally administered angiotensin II increases sympathetic activity in the rat
1987
Minireview: Overview of the Renin-Angiotensin System—An Endocrine and Paracrine System
2003
Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts.
1993
Inhibition of the Na+/H+Exchanger Confers Greater Cardioprotection Against 90 Minutes of Myocardial Ischemia Than Ischemic Preconditioning in Dogs
1999
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
Angiotensin II sensitive neurons in the supraoptic nucleus, subfornical organ and anteroventral third ventricle of rats in vitro
1987
Targeted Inactivation of the Ren-2 Gene in Mice
1996
Angiotensin I and II exert inotropic effects in atrial but not in ventricular human myocardium. An in vitro study under physiological experimental conditions.
1993
Effects of central infusion of ANG II and losartan on the cardiac baroreflex in rabbits
2000
In vivo activity of purified mouse brain renin
1981
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Molecular cloning of porcine soluble angiotensin-binding protein.
1992
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
2005 StandoutNobel
Early Induction of Angiotensin I–Converting Enzyme in Rat Carotid Artery After Balloon Injury
1997
Hypothalamic Integration: Organization of the Paraventricular and Supraoptic Nuclei
1983 Standout
Increased plasma arginine vasopressin levels in patients with congestive heart failure
1983
Hydroxymethylfurfural, A Versatile Platform Chemical Made from Renewable Resources
2013 Standout
Immunohistochemical localization of renin in luteinizing hormone-producing cells of rat pituitary.
1981
Construction and Validation of Improved Triple Fusion Reporter Gene Vectors for Molecular Imaging of Living Subjects
2007 StandoutNobel
Molecular phenotyping for analyzing subtle genetic effects in mice: Application to an angiotensinogen gene titration
2002 StandoutNobel

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3. Endothelin antagonists: discovery of EMD 122946, a highly potent and orally active ETA selective antagonist
1998
Pharmacological basis for antihypertensive therapy with a novel dopamine agonist
1992
Structure-Function Analysis of Reovirus Binding to Junctional Adhesion Molecule 1
2003
Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine‐based Compounds
2005
Non-Peptide Angiotensin II Receptor Antagonists: Synthesis and Biological Activity of a Series of Novel 4,5-Dihydro-4-oxo-3H-imidazo[4,5-c]pyridine Derivatives
1994
Nucleoside binding site ofHerpes simplex type 1 thymidine kinase analyzed by X-ray crystallography
2000
Effect of bimakalim (EMD 52692), an opener of ATP sensitive potassium channels, on infarct size, coronary blood flow, regional wall function, and oxygen consumption in swine
1994
Inhibitors of Ischemic Preconditioning Do Not Attenuate Na+/H+ Exchange Inhibitor Mediated Cardioprotection
2000
Biochemical and Structural Characterization of (South)-Methanocarbathymidine That Specifically Inhibits Growth of Herpes Simplex Virus Type 1 Thymidine Kinase-transduced Osteosarcoma Cells
2004
The Rational of Catalytic Activity of Herpes Simplex Virus Thymidine Kinase
2001
Iso-renin of extrarenal origin
1976
Effect of Saralasin and Atropine on Thirst induced by Water Deprivation
1977
Inhibition of drinking in water-deprived rats by combined central angiotensin II and cholinergic receptor blockade
1978
The Intrinsic Brain Iso-Renin-Angiotensin System in the Rat: Its Possible Role in Central Mechanisms of Blood Pressure Regulation
1974
Regulation of Brain Angiotensinogen in Renal Hypertensive Rats
1984
Cardiac output distribution during vasopressin infusion or dehydration in conscious dogs
1982
Uracil-based angiotensin II receptor antagonists
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Lowering of hypertension by central saralasin in the absence of plasma renin
1977 Nature
Angiotensin-converting enzyme blockade by captopril changes angiotensin II receptors and angiotensinogen concentrations in the brain of SHR-sp and wky rats
1982
Regulation of angiotensinogen in cerebrospinal fluid and plasma of rats
1983
Regional distribution of renin and angiotensinogen in the brain of normotensive (WKY) and spontaneously hypertensive (SHR) rats
1985
The brain renin--angiotensin system.
1981
Regulation of Angiotensinogen in the Central Nervous System
1983
Evidence for local angiotensin formation in brain of nephrectomized rats
1976
Pressor Action of Centrally Perfused Angiotensin II in Rats with Hereditary Hypothalamic Diabetes Insipidus
1976
Novel 4,5-dihydro-4-oxo-3H-imidazo[4,5-c]pyridines. Potent angiotensin II receptor antagonists with high affinity for both the AT1 and AT2 subtypes
1997
Increased sensitivity of neurons to angiotensin II in SHR as compared to WKY rats
1982
Na+/H+exchange inhibition prevents endothelial dysfunction after I/R injury
2001
THE ISO-RENIN ANGIOTENSIN SYSTEMS IN EXTRARENAL TISSUE
1976
The Renin and Iso-Renin-Angiotensin Systems in Rats with Experimental Pituitary Tumors
1975
A micromethod for the measurement of renin in brain nuclei: Its application in spontaneously hypertensive rats
1982
Angiotensin and cell growth
1991
Effects of angiotensin II and angiotensin II antagonist saralasin on cell growth and renin in 3T3 and SV3T3 cells
1979
In vivo enzyme activity of purified human brain renin
1978
Components of the Renin-Angiotensin System in the Cerebrospinal Fluid of Rats and Dogs with Special Consideration of the Origin and the Fate of Angiotensin II
1980
Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding
2003
Influence of captopril treatment on angiotensin II receptors and angiotensinogen in the brain of spontaneously hypertensive rats.
1983
Impermeability of the Blood—Cerebrospinal Fluid Barrier for Angiotensin II in Rats
1976
A New Sodium/Hydrogen Exchange Inhibitor, EMD 85131, Limits Infarct Size in Dogs When Administered Before or After Coronary Artery Occlusion
1998
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