Citation Impact
Citing Papers
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
2012 Standout
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines
2015
Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
2013 Science
Lnc RNA ‐dependent nuclear stress bodies promote intron retention through SR protein phosphorylation
2019
Illuminating the dark phosphoproteome
2019
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
2014 Standout
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity
2011
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Abiotic Stress Signaling and Responses in Plants
2016 Standout
Xylosyltransferase II is the predominant isoenzyme which is responsible for the steady-state level of xylosyltransferase activity in human serum
2015 StandoutNobel
High-Throughput Kinase Profiling: A More Efficient Approach toward the Discovery of New Kinase Inhibitors
2011
The (un)targeted cancer kinome
2010
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
A view on drug resistance in cancer
2019 StandoutNature
Protein promiscuity and its implications for biotechnology
2009
Turning promiscuous kinase inhibitors into safer drugs
2008
Mechanism and Regulation of NLRP3 Inflammasome Activation
2016 Standout
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
2013 Standout
The Intrinsically Disordered Protein Atg13 Mediates Supramolecular Assembly of Autophagy Initiation Complexes
2016 StandoutNobel
Regulation of chromatin by histone modifications
2011 Standout
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer
2010 StandoutNobel
CaMKII binding to GluN2B is critical during memory consolidation
2012
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
2010 Nature
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Protein kinase inhibition of clinically important staurosporine analogues
2010
Network pharmacology: the next paradigm in drug discovery
2008 Standout
The machinery of macroautophagy
2013 Standout
Recent insights into the complexity of Tank‐binding kinase 1 signaling networks: The emerging role of cellular localization in the activation and substrate specificity of TBK1
2013
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Mechanisms of CaMKII action in long-term potentiation
2012
Structures of parasitic CDPK domains point to a common mechanism of activation
2010
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Emerging cancer therapeutic opportunities by inhibiting mitotic kinases
2008
Phosphoinositide 3‐kinases in cell migration
2008
The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: A structural analysis of the binding interactions of Gleevec®, Nexavar®, and BIRB-796
2010
Targeting cancer with small molecule kinase inhibitors
2008 Standout
Structural genomics—Impact on biomedicine and drug discovery
2010
Drug repurposing: progress, challenges and recommendations
2018 Standout
An Atg13 Protein-mediated Self-association of the Atg1 Protein Kinase Is Important for the Induction of Autophagy
2011
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing
2011
Large‐scale prediction of drug–target relationships
2008
Non-kinase targets of protein kinase inhibitors
2017
Cell cycle regulation by the NEK family of protein kinases
2012
The unfolded protein response signals through high-order assembly of Ire1
2008 Nature
High-throughput kinase profiling as a platform for drug discovery
2008
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Comprehensive analysis of kinase inhibitor selectivity
2011 Standout
Filling out the structural map of the NTF2-like superfamily
2013
Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation
2013 Standout
Targeting the cancer kinome through polypharmacology
2010
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
2009 Standout
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Receptor subtype discrimination using extensive shape complementary designed interfaces
2019 StandoutNobel
Progress in the Discovery of Small-Molecule Inhibitors of Bromodomain–Histone Interactions
2011
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
2013 Standout
Protein methyltransferases as a target class for drug discovery
2009
Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
2012
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery
2008
Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold
2018 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Kinase selectivity potential for inhibitors targeting the ATP binding site: a network analysis
2009
Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response
2011
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
2010 Standout
Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors
2011
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
PlateletWeb: a systems biologic analysis of signaling networks in human platelets
2011
Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
2010 Standout
Selectively Nonselective Kinase Inhibition: Striking the Right Balance
2009
Marine Polysaccharides from Algae with Potential Biomedical Applications
2015 Standout
A Host of Factors Regulating Influenza Virus Replication
2010 StandoutNobel
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
The Halogen Bond
2016 Standout
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation
2011
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs
2019 Standout
Structural diversity of calmodulin binding to its target sites
2013
The Essential Medicinal Chemistry of Curcumin
2017 Standout
Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells
2015
Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology
2012 Standout
Works of P. Rellos being referenced
Structure and Regulation of the Human Nek2 Centrosomal Kinase
2006
Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation
2010
Kinase Domain Insertions Define Distinct Roles of CLK Kinases in SR Protein Phosphorylation
2009
Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites
2008
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases
2007