Citation Impact
Citing Papers
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
2010 StandoutNobel
Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor
2003 Standout
A model for the structure and functions of iron-responsive elements
1988
AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis
1996 Standout
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
1997 StandoutNature
A Mutation, in the Iron-Responsive Element of H Ferritin mRNA, Causing Autosomal Dominant Iron Overload
2001
Oncogenic kinase signalling
2001 StandoutNature
Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL
1997
Nuclear magnetic resonance detection of bound water molecules in the active site of Lactobacillus casei dihydrofolate reductase in aqueous solution
1992
Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo
2003
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Balancing Acts
2004 Standout
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
1998
A fine-structure deletion map of human chromosome 11p: Analysis of J1 series hybrids
1989
Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins
1992
The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family
2000 StandoutNobel
Isoforms of ferritin have a specific cellular distribution in the brain
1994
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1999 StandoutNature
STATs in oncogenesis
2000 Standout
Regulation of the C. elegans molt by pqn-47
2011 StandoutNobel
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
2005 Standout
NMR observation of individual molecules of hydration water bound to DNA duplexes: direct evidence for a spine of hydration water present in aqueous solution
1992 StandoutNobel
Mechanisms and functions of eph and ephrin signalling
2002 Standout
A functional Jak2 tyrosine kinase domain is essential for mouse development
2006 StandoutNobel
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
2011 Standout
p21 is a universal inhibitor of cyclin kinases
1993 StandoutNature
A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome
2002
Disabling Abl—Perspectives on Abl kinase regulation and cancer therapeutics
2002
The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA
2002
Protein tyrosine kinases and cancer
1997
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
2002 Standout
cDNA cloning and genomic structure of a novel gene (C11orf9) localized to chromosome 11q12→q13.1 which encodes a highly conserved, potential membrane-associated protein
2000
Specificity and mechanism of action of some commonly used protein kinase inhibitors
2000 Standout
Cytokine Signaling in 2002
2002 Standout
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α
1998 StandoutNobel
Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
1994 Standout
Neurodegenerative diseases and oxidative stress
2004 Standout
The human U1 snRNP-Specific U1A protein inhibits polyadenylation of its own pre-mRNA
1993
A Human Mitochondrial Ferritin Encoded by an Intronless Gene
2001
Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase
2003 Standout
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
1993 Standout
A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders
2005 Standout
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
1999 Standout
Prolonged exercise induces angiogenesis and increases cerebral blood volume in primary motor cortex of the rat
2003 StandoutNobel
Biochemical analysis of TREX complex recruitment to intronless and intron‐containing yeast genes
2004 StandoutNobel
Mammalian G1 cyclins
1993 Standout
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
1999 StandoutScience
Posttranslational modification of TEL and TEL/AML1 by SUMO-1 and cell-cycle-dependent assembly into nuclear bodies
2000
Cloning and expression of the gene encoding Lactobacillus casei folylpoly-gamma-glutamate synthetase in Escherichia coli and determination of its primary structure.
1990
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
2003 Standout
A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.
1987
Identification of chromophore binding domains of yeast DNA photolyase.
1992 StandoutNobel
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
1990 Standout
After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies
2004
Structural features in eukaryotic mRNAs that modulate the initiation of translation.
1991 Standout
Transforming property of TEL-FGFR3 mediated through PI3-K in a T-cell lymphoma that subsequently progressed to AML
2004
Oligomeric Structure of the Human EphB2 Receptor SAM Domain
1999 Science
Controlling mRNA lifespan
1988 StandoutNatureNobel
Maternal mRNA from clam oocytes can be specifically unmasked in vitro by antisense RNA complementary to the 3'-untranslated region.
1990 StandoutNobel
Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo.
1990
Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation
1988 Science
Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes
1991 StandoutNobel
TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia
1996
The molecular biology of chronic myeloid leukemia
2000
The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion
2000
The TEL/platelet-derived growth factor β receptor (PDGFβR) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGFβR kinase-dependent signaling pathways
1996
Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.
1991 StandoutNobel
TEL-JAK2 transgenic mice develop T-cell leukemia
2000
Fusion of TEL, the ETS-Variant Gene 6 (ETV6), to the Receptor-Associated Kinase JAK2 as a Result of t(9; 12) in a Lymphoid and t(9; 15; 12) in a Myeloid Leukemia
1997
High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia
1995
The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products.
1996
Protein Modification by SUMO
2004 Standout
Proteins Binding to 5′ Untranslated Region Sites: a General Mechanism for Translational Regulation of mRNAs in Human and Yeast Cells
1994
CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TEL-PDGFR Fusion Proteins
1997
Coordinated Regulation of Iron-Controlling Genes, H-Ferritin and IRP2 , by c-MYC
1999 Science
Socs-1 Inhibits TEL-JAK2-Mediated Transformation of Hematopoietic Cells through Inhibition of JAK2 Kinase Activity and Induction of Proteasome-Mediated Degradation
2001
CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TEL-PDGFR Fusion Proteins
1997
c-Abl Regulates p53 Levels under Normal and Stress Conditions by Preventing Its Nuclear Export and Ubiquitination
2001 StandoutNobel
ARG tyrosine kinase activity is inhibited by STI571
2001
Fusion of ETV6 to fibroblast growth factor receptor 3 in peripheral T-cell lymphoma with a t(4;12)(p16;p13) chromosomal translocation.
2001
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Oxidative stress in neurodegeneration: cause or consequence?
2004 Standout
TEL-JAK2 transgenic mice develop T-cell leukemia
2000
Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA.
1991
Works of P. Papadopoulos being referenced
Identification of two human ferritin H genes on the short arm of chromosome 6
1990
Nucleotide sequence of the dihydrofolate reductase gene of methotrexate-resistant Lactobacillus casei
1985
The novel activation of ABL by fusion to an ets-related gene, TEL.
1995
Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene.
1986