Citation Impact
Citing Papers
Predominant Autoantibody Production by Early Human B Cell Precursors
2003 StandoutScience
Diversification, not use, of the immunoglobulin VH gene repertoire is restricted in DiGeorge syndrome.
1993 StandoutNobel
Somatic hypermutation in normal and transformed human B cells
1998
Linking class-switch recombination with somatic hypermutation
2001 StandoutNobel
Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage
1998 StandoutNobel
Cloning and sequencing of human immunoglobulin λ. gene segments
1993 StandoutNobel
Molecular mimicry between bacterial and self antigen in a patient with systemic lupus erythematosus
1999
Crystal Structure of HEL4, a Soluble, Refoldable Human VH Single Domain with a Germ-line Scaffold
2004 StandoutNobel
Human Immunoglobulin Heavy-Chain Variable Region Genes: Organization, Polymorphism, and Expression
1991
PDB-based protein loop prediction: parameters for selection and methods for optimization
1997 StandoutNobel
Somatic insertions and deletions shape the human antibody repertoire 1 1Edited by J. Karn
1999 StandoutNobel
Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locus
1993 StandoutNobel
Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor
1999 StandoutNobel
Delta-induced Notch Signaling Mediated by RBP-J Inhibits MyoD Expression and Myogenesis
1999 StandoutNobel
HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin VHlocus
1993 StandoutNobel
The Biologic Significance of Human Natural Autoimmune Responses: Relationship to the Germline, Early Immune and Malignant B Cell Variable Gene Repertoire
1990
Antibody framework residues affecting the conformation of the hypervariable loops
1992 StandoutNobel
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Organization of the Human Immunoglobulin Heavy-Chain Locus
1996
A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles.
1993
Restricted immunoglobulin VH usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of monospecific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with self antigens.
1993
Physical map of the 3′ region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotype.
1991 StandoutNobel
Immune Thrombocytopenic Purpura
2002 Standout
Combinatorial infection andin vivorecombination: a strategy for making large phage antibody repertoires
1993 StandoutNobel
By-passing immunisation
1992 StandoutNobel
The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement
1994
Molecular characterization of the human immunoglobulin VλI germline gene repertoire
1992
An Antibody Fragment from a Phage Display Library Competes for Ligand Binding to the Low Density Lipoprotein Receptor Family and Inhibits Rhinovirus Infection
1995 StandoutNobel
Thermodynamically Stable Aggregation-Resistant Antibody Domains through Directed Evolution
2008 StandoutNobel
A Segment of Human Vh Gene Locus is Duplicated
1990
Molecular Characterization of Variable Heavy and Light Chain Regions of Five HIV Type 1-Specific Human Monoclonal Antibodies*
1994
A human monoclonal IgA rheumatoid factor using the VkIV light chain gene
1992
Type 1 diabetes
2013 Standout
Sickle-cell disease
2010 Standout
Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.
1992 StandoutNobel
By–Passing Immunization: Building High Affinity Human Antibodies by Chain Shuffling
1992 StandoutNobel
Human Antibody Fragments Specific for Human Blood Group Antigens from a Phage Display Library
1993 StandoutNobel
Antiphospholipid antibodies, proteins C and S, and coagulation changes in sickle cell disease
1999
Autoantibodies and the Fetal Antibody Repertoire
1990
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Vλ and Jλ‐Cλ gene segments of the human immunoglobulin λ light chain locus are separated by 14 kb and rearrange by a deletion mechanism
1991
Rheumatoid Factor Autoantibodies in Health and Diseasea
1997
The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes.
1990
Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, “minor” D segments or D-D recombination 1 1Edited By J. Karn
1997 StandoutNobel
Mapping of Novel Genes Predisposing or Protecting Diabetes Development in the BB/OK Rat
1998
The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops
1992 StandoutNobel
Structural repertoire of the human VH segments
1992 StandoutNobel
Surface Display of Proteins on Bacteriophage λ Heads
1996 StandoutNobel
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
From Human Autoantibodies to the Fetal Antibody Repertoire to B Cell Malignancy: It's a Small World After All
1990
Analysis of immunoglobulin variable region genes from human IgG anti‐DNA hybridomas
1992
Guiding the Selection of Human Antibodies from Phage Display Repertoires to a Single Epitope of an Antigen
1994 StandoutNobel
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Restricted use of fetal VH3 immunoglobulin genes by unselected B cells in the adult. Predominance of 56p1-like VH genes in common variable immunodeficiency.
1992
Analysis of Heavy and Light Chain Pairings Indicates that Receptor Editing Shapes the Human Antibody Repertoire
1999 StandoutNobel
A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q
1994 StandoutNobel
Chromosomal organization of the heavy chain variable region gene segments comprising the human fetal antibody repertoire.
1992
A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs
2001 StandoutNobel
Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines
1994 StandoutNobel
Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia
2007 StandoutNobel
Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents.
1994 StandoutNobel
Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments.
1994
A deletion map of the human immunoglobulin heavy chain variable region.
1991
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus
2001 StandoutNobel
Recombinant human natural autoantibodies against GPIIb/IIIa inhibit binding of autoantibodies from patients with AITP
1998
Human rheumatoid factor cross-idiotypes. IV. Studies on WA XId-positive IgM without rheumatoid factor activity provide evidence that the WA XId is not unique to rheumatoid factors and is distinct from the 17.109 and G6 XIds.
1993
Clonally-related Immunoglobulin VH Domains and Nonrandom Use of DH Gene Segments in Rheumatoid Arthritis Synovium
1998
Making Antibodies by Phage Display Technology
1994 StandoutNobel
GENETIC SUSCEPTIBILITY TO SYSTEMIC LUPUS ERYTHEMATOSUS
1998
"Diabodies": small bivalent and bispecific antibody fragments.
1993 StandoutNobel
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
2003 Standout
Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factors.
1993
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Accumulation of B Lymphocytes with a Naive, Resting Phenotype in a Subset of Hepatitis C Patients
2003 StandoutNobel
The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
1998 StandoutNobel
Human anti-self antibodies with high specificity from phage display libraries.
1993
GENETICS OF SYSTEMIC LUPUS ERYTHEMATOSUS
1992
Works of P P Chen being referenced
A highly informative probe for two polymorphic Vh gene regions that contain one or more autoantibody-associated Vh genes.
1989
A systematic approach to defining the germline gene counterparts of a mutated autoantibody from a patient with rheumatoid arthritis
1992
Molecular basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseases.
1991
A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation.
1989
The incidence of a new human cross-reactive idiotype linked to subgroup VHIII heavy chains
1990
Defining the genetic origins of three rheumatoid synovium-derived IgG rheumatoid factors.
1994
A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice.
1996
Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases.
1990