Citation Impact
Citing Papers
Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis
2005 Standout
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
P-glycoprotein and multidrug resistance protein activities in relation to treatment outcome in acute myeloid leukemia.
2000
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
1994
ATP-Dependent Efflux of CPT-11 and SN-38 by the Multidrug Resistance Protein (MRP) and Its Inhibition by PAK-104P
1999
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
A Novel Subtype of the Prostacyclin Receptor Expressed in the Central Nervous System
1996 StandoutNobel
Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis
2002
Visible light photoredox catalysis: applications in organic synthesis
2010 Standout
Catalytic Carbophilic Activation: Catalysis by Platinum and Gold π Acids
2007 Standout
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
2005 Standout
Preferential Inhibition of T Helper 1, but Not T Helper 2, Cytokines in Vitro by L-826,141 [4-{2-(3,4-Bisdifluromethoxyphenyl)-2-{4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl}-3-methylpyridine-1-oxide], a Potent and Selective Phosphodiesterase 4 Inhibitor
2004
International Union of Pharmacology XXXVII. Nomenclature for Leukotriene and Lipoxin Receptors
2003
Catalysis for fluorination and trifluoromethylation
2011 StandoutNature
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Fluorine in Medicinal Chemistry
2015
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells
2003 Standout
The next generation of PDE4 inhibitors
2001
Regulation of Mucous Cell Metaplasia in Bronchial Asthma
2008
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy
1992
Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
1999
Gastrointestinal Toxicity of Nonsteroidal Antiinflammatory Drugs
1999 Standout
Synthesis of multisubstituted quinolines from Baylis–Hillman adducts obtained from substituted 2-chloronicotinaldehydes and their antimicrobial activity
2006
Airway Mucus Function and Dysfunction
2010 Standout
cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats
1996
Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials
2009
Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding
2002
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Practical Route to a New Class of LTD4 Receptor Antagonists
1996
Fluorine in medicinal chemistry
2007 Standout
Oxidative inactivation of leukotriene C 4 by stimulated human polymorphonuclear leukocytes
1982 StandoutNobel
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
1996 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
A glutathione conjugate of hepoxilin A3: formation and action in the rat central nervous system.
1990 StandoutNobel
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
Anti-cancer-prostaglandin-induced cell-cycle arrest and its modulation by an inhibitor of the ATP-dependent glutathione S-conjugate export pump (GS-X pump)
1998 StandoutNobel
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
2000 Standout
Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation
1983 StandoutScienceNobel
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Shock and Tissue Injury Induced by Recombinant Human Cachectin
1986 StandoutScienceNobel
A Scaleable Synthesis of Methyl 3-Amino-5-(4-fluorobenzyl)-2-pyridinecarboxylate
2007
Retention of Configuration in Photolytic Decarboxylation of Peresters to Form Chiral Acetals and Ethers
2008
α-Fluorinated Ethers, Thioethers, and Amines: Anomerically Biased Species
2005
A new general method for the synthesis of lipoxygenase products: preparation of ±5-HETE
1983
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Biological activities of a chemically synthesized form of leukotriene E4
1981
Cascade Processes of Metallo Carbenoids
1996 Standout
The effect of indomethacin on the contractile response of the guinea‐pig lung parenchymal strip to leukotrienes B4, C4, D4 and E4
1983 StandoutNobel
Release of platelet‐activating factor (PAF‐acether) and leukotrienes C and D from inflammatory macrophages
1982
Effect of Dietary Enrichment with Eicosapentaenoic and Docosahexaenoic Acids on in Vitro Neutrophil and Monocyte Leukotriene Generation and Neutrophil Function
1985 StandoutNobel
The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology.
1984
IL-4 Receptor Signaling in Clara Cells Is Required for Allergen-Induced Mucus Production
2005
Increased Acute Inflammation, Leukotriene B4-Induced Chemotaxis, and Signaling in Mice Deficient for G Protein-Coupled Receptor Kinase 6
2003 StandoutNobel
Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis
2002
Regioselective Friedel−Crafts Alkylation of Anilines and Amino‐Substituted Heteroarenes with Hexafluoroacetone Sesquihydrate
2003
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.
1981 StandoutNobel
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Facile Synthesis of a Family of H8BINOL-Amine Compounds and Catalytic Asymmetric Arylzinc Addition to Aldehydes
2010
Process Development and Large-Scale Synthesis of a PDE4 Inhibitor
2005
Helicenes: Synthesis and Applications
2011 Standout
Synthesis of ± 8- and 9-HETEs
1984
Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.
1984 StandoutNobel
Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, and Other Derivatives of Carbon‐20 Unsaturated Fatty Acids
1982
Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
2010 StandoutNobel
Choroid plexus epithelial expression of MDR 1 P glycoprotein and multidrug resistance-associated protein contribute to the blood–cerebrospinal-fluid drug-permeability barrier
1999
Metalated Heterocycles and Their Applications in Synthetic Organic Chemistry
2004
Functional Oligothiophenes: Molecular Design for Multidimensional Nanoarchitectures and Their Applications
2009 Standout
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects
1987 StandoutScienceNobel
A Novel Approach to 2-Arylated Quinolines: Electrocyclization of Alkynyl Imines via Vinylidene Complexes
2004
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Practical Asymmetric Synthesis of a Potent PDE4 Inhibitor via Stereoselective Enolate Alkylation of a Chiral Aryl−Heteroaryl Secondary Tosylate
2005
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Sequential conversion of the glutathionyl side chain of slow reacting substance (SRS) to cysteinyl-glycine and cysteine in rat basophilic leukemia cells stimulated with A-23187
1980
Nonracemic Synthesis of GK–GKRP Disruptor AMG-3969
2014
Secretory products of macrophages.
1987 Standout
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Leukotriene C4 affects pulmonary and cardiovascular dynamics in monkey
1982 StandoutNatureNobel
The Allylic Azide Rearrangement: Achieving Selectivity
2005 StandoutNobel
Catalytic Asymmetric Transacetalization
2010 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Recent advances in the preparation and synthetic applications of oxiranes
1983
Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process
1990
Transformation of arachidonic acid in leukocytes. isolation and structural analysis of a novel dihydroxy derivative
1981
Works of P. Masson being referenced
Comparison of inhibition of ovalbumin-induced bronchoconstriction in guinea pigs and in vitro inhibition of tumor necrosis factor-α formation with phosphodiesterase 4 (PDE4) selective inhibitors
2002
Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist
1990
Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor
2002
Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist
1989
Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors
2003
Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters
2002
Gob-5 Is Not Essential for Mucus Overproduction in Preclinical Murine Models of Allergic Asthma
2005
Differing mechanisms for leukotriene D4-induced bronchoconstriction in guinea pigs following intravenous and aerosol administration
1982
Comparative study of the pulmonary effects of intravenous leukotrienes and other bronchoconstrictors in anaesthetized guinea pig
1985
Biological activity of leukotriene sulfones on respiratory tissues
1982
Hunting the Emesis and Efficacy Targets of PDE4 Inhibitors: Identification of the Photoaffinity Probe 8-(3-Azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ)
2000
The synthesis of a leukotriene with SRS-like activity
1980
The activity of synthetic leukotriene C-1 on guinea pig trachea and ileum
1980