Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Surface Sites for Engineering Allosteric Control in Proteins
2008 Science
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
The phosphorylation status of PAS‐B distinguishes HIF‐1α from HIF‐2α in NBS1 repression
2006
Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin α/β pathway
2007
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Hypoxia Increases Sirtuin 1 Expression in a Hypoxia-inducible Factor-dependent Manner
2011
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Structural integration in hypoxia-inducible factors
2015 Nature
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases
2008
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α
2007
Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors
2010
Composition and function of cytochrome c biogenesis System II
2011
Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase
2009 StandoutNobel
Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly
2013
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis
2008 StandoutNobel
Effects of hypoxia on tumor metabolism
2007
Oxygen Sensing and the Activation of the Hypoxia Inducible Factor 1 (HIF-1)– Invited Article
2009
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Strategies for development of dengue virus inhibitors
2010
Network medicine: a network-based approach to human disease
2010 Standout
Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?
2007
Functional Characterization of cis and trans Activity of the Flavivirus NS2B-NS3 Protease
2007
Structurally Mapping Endogenous Heme in the CcmCDE Membrane Complex for Cytochrome c Biogenesis
2018 StandoutNobel
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity
2007 StandoutNobel
Conditional HIF-1α Expression Produces a Reversible Cardiomyopathy
2010
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
The Rise and Fall of the Chemoattractant Receptor GPR33
2005 StandoutNobel
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions
2010 StandoutNobel
Mechanism of Photosignaling by Drosophila Cryptochrome
2013 StandoutNobel
The expanding diversity of serine hydrolases
2007
The human oxygen sensing machinery and its manipulation
2008
Design of activated serine–containing catalytic triads with atomic-level accuracy
2014 StandoutNobel
Atomic-level characterization of disordered protein ensembles
2007
A survey of the year 2002 commercial optical biosensor literature
2003
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
Effect of N-linked glycosylation on glycopeptide and glycoprotein structure
1999
FHL family members suppress vascular endothelial growth factor expression through blockade of dimerization of HIF1α and HIF1β
2012
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
2013
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock
2014 StandoutNobel
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status
2008 StandoutNobel
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Progress in the Discovery of Small-Molecule Inhibitors of Bromodomain–Histone Interactions
2011
Cytochrome c biogenesis: the Ccm system
2010
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Replication of hepatitis C virus
2007 StandoutNobel
Redox Processes Controlling the Biogenesis of c -Type Cytochromes
2010
Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution
2007
Roles of N-Linked Glycans in the Endoplasmic Reticulum
2004 Standout
Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing
2013 StandoutNobel
Chemoselective Ligation Applied to the Synthesis of a Biantennary N-Linked Glycoform of CD52
2003 StandoutNobel
Vascular Responses to Hypoxia and Ischemia
2009 StandoutNobel
The structural basis of g-protein-coupled receptor function and dysfunction in human diseases
2007
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Yellow Fever Virus NS3 Plays an Essential Role in Virus Assembly Independent of Its Known Enzymatic Functions
2008
Inhibiting Hypoxia-Inducible Factor 1 for Cancer Therapy
2006
Emerging Models for the Molecular Basis of Mammalian Circadian Timing
2014
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
The C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral Replication
2007 StandoutNobel
Tripping the Light Fantastic: Blue-Light Photoreceptors as Examples of Environmentally Modulated Protein−Protein Interactions
2010
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
2018 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
2009
Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor
2013
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Pharmaceutical Machine Learning: Virtual High-Throughput Screens Identifying Promising and Economical Small Molecule Inhibitors of Complement Factor C1s
2018
PubChem in 2021: new data content and improved web interfaces
2020 Standout
Light-Induced Subunit Dissociation by a Light–Oxygen–Voltage Domain Photoreceptor from Rhodobacter sphaeroides
2012
Works of P. Erbel being referenced
Structural Basis of ARNT PAS-B Dimerization: Use of a Common Beta-sheet Interface for Hetero- and Homodimerization
2005
Structural basis for PAS domain heterodimerization in the basic helix–loop–helix-PAS transcription factor hypoxia-inducible factor
2003
Fragment-Based Screening by Biochemical Assays: Systematic Feasibility Studies with Trypsin and MMP12
2010
Structural Determinants of MALT1 Protease Activity
2012
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus
2006
Functions of the Per/ARNT/Sim Domains of the Hypoxia-inducible Factor
2005
Studies on the relevance of the glycan at Asn-52 of the α-subunit of human chorionic gonadotropin in the αβ dimer
2002
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors
2017
Solution structure of the α‐subunit of human chorionic gonadotropin
1999
Mechanism of substrate specificity in Bacillus subtilis ResA, a thioredoxin-like protein involved in cytochrome c maturation
2006 Nobel