Citation Impact
Citing Papers
Role of Genotype in the Cycle of Violence in Maltreated Children
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Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
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Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
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Mitochondrial Dysfunction in Neurodegeneration
1997
Cancer chemoprevention with dietary phytochemicals
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Neuronal-specific expression of human copper-zinc superoxide dismutase gene in transgenic mice: animal model of gene dosage effects in Down's syndrome
1991
Regulation of cell death: the calcium–apoptosis link
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A Critical Evaluation of Influence of Ethanol and Diet on Salsolinol Enantiomers in Humans and Rats
2009
Mitochondria determine the survival and death in apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, and neuroprotection by propargylamines
2002
Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells
2002
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
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An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH‐SY5Y cells
2003
An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic Bcl-2 in human dopaminergic SH-SY5Y cells
2002
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1998 StandoutNature
Hydrogen peroxide mediates amyloid β protein toxicity
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Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression
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The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances
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Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
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Valproic acid‐mediated Hsp70 induction and anti‐apoptotic neuroprotection in SH‐SY5Y cells
2005
The Pictet–Spengler Reaction in Nature and in Organic Chemistry
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Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease
2005
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
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Oxidative DNA damage and cytotoxicity induced by copper-stimulated redox cycling of salsolinol, a neurotoxic tetrahydroisoquinoline alkaloid
2001
Mitochondrial control of cell death
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Contributory mechanisms in the causation of neurodegenerative disorders
1993
Deracemization of��-Methylbenzylamine Using an Enzyme Obtained by In Vitro Evolution
2002
Future of neuroprotection in Parkinson's disease
2001
A Five-Year Study of the Incidence of Dyskinesia in Patients with Early Parkinson's Disease Who Were Treated with Ropinirole or Levodopa
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Superoxide dismutase, aging, and degenerative disease
1994
Diabetic neuropathy: scope of the syndrome
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Sex-dependent differences in the effects of aging on antioxidant defense mechanisms of rat liver
1991
Organocatalytic Asymmetric Hydrolysis of Epoxides
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Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
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Diabetic foot ulcers
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Enantioselective Enzymes by Computational Design and In Silico Screening
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Mitochondrial Membrane Permeabilization in Cell Death
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Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V)
2001
Role of mitochondria in the etiology and pathogenesis of Parkinson's disease
1995
Epoxide hydrolases: their roles and interactions with lipid metabolism
2005
Oxidative Stress in Mitochondria: Decision to Survival and Death of Neurons in Neurodegenerative Disorders
2005
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
Major Depressive Disorder
2008 Standout
Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
2002
Isoquinoline neurotoxins in the brain and Parkinson's disease
1997
Chlorinative stress: An under appreciated mediator of neurodegeneration?
2006
A bioluminescent assay for monoamine oxidase activity
2006
NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats
1992
Synthesis and antimicrobial activity of some novel derivatives of benzofuran: Part 2. The synthesis and antimicrobial activity of some novel 1-(1-benzofuran-2-yl)-2-mesitylethanone derivatives
2007
Increased susceptibility to MPTP toxicity in middle-aged rhesus monkeys
1995
Oxidative stress: Free radical production in neural degeneration
1994
Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long term losses of dopamine neurons in offspring a potential new model of parkinson s disease
2003
Dopamine-Derived Salsolinol Derivatives as Endogenous Monoamine Oxidase Inhibitors: Occurrence, Metabolism and Function in Human Brains
2003
Direct enantiomeric separations by high performance liquid chromatography using cyclodextrins
1997
Cell death in Parkinson's disease
2002
Mitochondrial permeability transition mediates apoptosis induced by N‐methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl‐2 and rasagiline, N‐propargyl‐1(R)‐aminoindan
2002
Trends in the Development of New Antidepressants. Is there a Light at the End of the Tunnel?
2004
Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease
1999
Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives
2005
Parkinson's Disease
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The clinical pharmacologic profile of reboxetine: does it involve the putative neurobiological substrates of wellbeing?
1998
Redox cycling of MPP+: Evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase
1993
Levodopa-Induced Neurotoxicity
1997
Oxidants, antioxidants, and the degenerative diseases of aging.
1993 Standout
Expression of Concern: Glycogen synthase kinase 3β (GSK3β) mediates 6‐ hydroxydopamine‐induced neuronal death
2004
Nucleophilic addition versus electron transfer in carbonylmetallate salts. Donor-acceptor interactions in the precursor ion pairs
1997
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
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Human Immunodeficiency Virus Induces a Dual Regulation of Bcl-2, Resulting in Persistent Infection of CD4+T- or Monocytic Cell Lines
1998 StandoutNobel
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
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Organic Photoredox Catalysis
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A facile and efficient asymmetric synthesis of (+)-salsolidine
2000
The Free Radical Theory of Aging Matures
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Copper Active Sites in Biology
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Synthesis and Photocatalytic Properties of Mixed Polyoxometalate−Porphyrin Copolymers Obtained from Anderson-Type Polyoxomolybdates
2009
Luminescent Chemodosimeters for Bioimaging
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Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
2000 Standout
Deracemization of��-Methylbenzylamine Using an Enzyme Obtained by In Vitro Evolution
2002
Escitalopram versus citalopram: the surprising role of the R-enantiomer
2004
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Review: A History of Cyclodextrins
2014 Standout
A general procedure for the asymmetric synthesis of 3-aryl-1,2,3,4-tetrahydroisoquinolines
2003
Oxidative Stress, Caloric Restriction, and Aging
1996 StandoutScience
The influence of substitution on the reduction mechanism and stability of reduction intermediates in 1,1′-phenylene-, 1,1′-diphenylene- and 1,1′-polymethylene-bispyridinium dications
1992
Recent Advances in Polyoxometalate-Catalyzed Reactions
2015 Standout
Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
1994 StandoutScience
Brain aging phenomena in migrating sockeye salmon Oncorhynchus nerka nerka
2005
Age-dependent increase in hydrogen peroxide production by cardiac monoamine oxidase A in rats
2003
Asymmetric Synthesis of Isoquinoline Alkaloids
2004 Standout
Asymmetric synthesis of 1-vinyltetrahydroisoquinoline through Pd-catalyzed intramolecular allylic amination
2007
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Novel Neuroprotective Mechanism of Action of Rasagiline Is Associated with Its Propargyl Moiety: Interaction of Bcl‐2 Family Members with PKC Pathway
2005
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
2002 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
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Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC)
2003 Standout
Simultaneous Voltammetric Detection of Salsolinol and Uric Acid in the Presence of High Concentration of Ascorbic Acid with Gold Nanoparticles/Functionalized Multiwalled Carbon Nanotubes Composite Film Modified Electrode
2009
Mechanically induced intramolecular electron transfer in a mixed-valence molecular shuttle
2012 StandoutNobel
Oxidative Stress, Cell Activation and Viral Infection
1994
Convenient enantioselective preparation of salsolinol-1-carboxylic acid
1997
Neurotoxins and neurotoxic species implicated in neurodegeneration
2004
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Catalytic Asymmetric Pictet−Spengler Reaction
2006 StandoutNobel
Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA
1995 Science
P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.
1996
Oxidative stress in neurodegeneration: cause or consequence?
2004 Standout
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of P. Dostert being referenced
Stereospecific occurrence of a parkinsonism-inducing catechol isoquinoline, n-methyl(R)salsolinol, in the human intraventricular fluid
1996
Enantiomeric composition of urinary salsolinol in Parkinsonian patients after Madopar
1989
Binding of 1,2(N)-dimethyl-6,7-dihydroxy-isoquinolinium ion to melanin: Effects of ferrous and ferric ion on the binding
1994
Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases
1988
A dopaminergic neurotoxin, (R)‐N‐methylsalsolinol, increases in parkinsonian cerebrospinal fluid
1996
Ratio of the R and S enantiomers of salsolinol in food and human urine
1989
Enantio-selective occurrence of (S)-tetrahydropapaveroline in human brain
2000
Inhibition of Tyrosine Hydroxylase by R and S Enantiomers of Salsolinol, 1‐Methyl‐6,7‐Dihydroxy‐1,2,3,4‐ Tetrahydroisoquinoline
1992
Contribution of Amine Oxidases to the Metabolism of Xenobiotics
1994
Enzymatic oxidation of the dopaminergic neurotoxin, 1 (R), 2(N)-Dimethyl-6,7-Dihydroxy-l,2,3,4-Tetrahydroisoquinoline, into 1,2(N)-Dimethyl-6,7-Dihydroxyisoquinolinium ion
1995
Time-dependence and differential induction of rat and guinea pig peroxisomalβ-oxidation, palmitoyl-CoA hydrolase, cytosolic and microsomal epoxide hydrolase after treatment with hypolipidemic drugs
1988
A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain
1997
Enantio-specific induction of apoptosis by an endogenous neurotoxin, N -methyl( R )salsolinol, in dopaminergic SH-SY5Y cells: suppression of apoptosis by N -(2-heptyl)- N -methylpropargylamine
2001
Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines
1998
Cytotoxicity of endogenous isoquinolines to human dopaminergic neuroblastoma SH-SY5Y cells
1997
Naturally-occurring isoquinolines perturb monoamine metabolism in the brain: studied by in vivo microdialysis
1993
Urinary elimination of salsolinol enantiomers in alcoholics
1991
Influence of food intake on the enantiomeric composition of urinary salsolinol in man
1989
Interactions of monoamine oxidase with substrates and inhibitors
1989
Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies
1996
A novel enzyme enantio-selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol
1996
Effects of various tetrahydroisoquinoline derivatives on mitochondrial respiration and the electron transfer complexes
1998
Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor
1997
An Endogenous Dopaminergic Neurotoxin, N‐Methyl‐(R)‐Salsolinol, Induces DNA Damage in Human Dopaminergic Neuroblastoma SH‐SY5Y Cells
1997
Dopamine‐Derived 1‐Methyl‐6,7‐Dihydroxyisoquinolines as Hydroxyl Radical Promoters and Scavengers in the Rat Brain: In Vivo and In Vitro Studies
1995
Stereoselective and species‐dependent kinetics of reboxetine in mouse and rat
1995
Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system
1994
Dopaminergic neurotoxins, 6,7-dihydroxy-1-(3′,4′-dihydroxybenzyl)-isoquinolines, cause different types of cell death in SH-SY5Y cells: apoptosis was induced by oxidized papaverolines and necrosis by reduced tetrahydropapaverolines
2000
N-methyl(r)salsolinol produces hydroxyl radicals: Involvement to neurotoxicity
1995
Inhibition of type a monoamine oxidase by 2(N)-methyl-6,7-dihydroxyisoquinolinium ions
1994
N-Methyl-(R)salsolinol as a dopaminergic neurotoxin: From an animal model to an early marker of Parkinson’s disease
1997
Presence of 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, novel endogenous amines, in parkinsonian and normal human brains
1991
Effect of ageing on tissue levels of amino acids involved in the nitric oxide pathway in rat brain
1993
Assay for the (R)- and (S)-enantiomers of salsolinols in biological samples and foods with ion-pair high-performance liquid chromatography using β-cyclodextrin as a chiral mobile phase additive
1997
Inhibition of type A and B monoamine oxidase by 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines and their N-methylated derivatives
1993
Monoamine oxidase, brain ageing and degenerative diseases
1989
Determination of the (R)- and (S)-enantiomers of salsolinol and N-methylsalsolinol by use of a chiral high-performance liquid chromatographic column
1995
Age‐Related Changes in Aldehyde Dehydrogenase Activity of Rat Brain, Liver, and Heart
1983
Synthesis and Anticonvulsant Activity of a New Class of 2-[(Arylalkyl)amino]alkanamide Derivatives
1998
Aldose reductase inhibitors
2015
One-electron and two-electron reductions of 1-methyl-4-phenyl pyridinium (MPP+)
1988
Developmental Aspects of theMonoamine-Degrading EnzymeMonoamine Oxidase
1992
Synthesis of the R and S enantiomers of 1,2,3,4-tetrahydro-6,7-dihydroxy-1-methylisoquinoline-1-carboxylic acid
1992
Synthesis and antiarrhythmic activity of new benzofuran derivatives
1981
Differential Changes in Superoxide Dismutase Activity in Brain and Liver of Old Rats and Mice
1983
The Anticonvulsant FCE 26743 is a Selective and Short-acting MAO-B Inhibitor Devoid of Inducing Properties towards Cytochrome P450-dependent Testosterone Hydroxylation in Mice and Rats
1994
Induction and autoinduction properties of rifamycin derivatives: a review of animal and human studies.
1994
Mechanism of Enantioseparation of Salsolinols, Endogenous Neurotoxins in Human Brain, with Ion-Pair Chromatography Using β-Cyclodextrin as a Mobile Phase Additive
1996
Age-related changes in benzylamine oxidase activity in rat tissues
1984