Citation Impact
Citing Papers
Toll Pathway-Dependent Blockade of CD4 + CD25 + T Cell-Mediated Suppression by Dendritic Cells
2003 StandoutScience
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Use of Anti-Tumor Necrosis Factor Antibodies in Rheumatoid Arthritis
1994
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Deactivation of vascular endothelium by monoclonal anti–tumor necrosis factor α antibody in rheumatoid arthritis
1996
A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer
2008
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
TNF and EPO: major players in the innate immune response: their discovery
2012
Inflammation and cancer
2002 StandoutNature
TNF Inhibitors are Produced Spontaneously by Rheumatoid and Osteoarthritic Synovial Joint Cell Cultures: Evidence of Feedback Control of TNF Action
1995
Involvement of macrophage migration inhibitory factor in the evolution of rat adjuvant arthritis
1998
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
In vivo production of interleukin‐10 by non–t cells in rheumatoid arthritis, sjöugren's syndrome, and systemic lupus erythematosus.
1994
Autoimmune Diseases
2001
Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases
1997 Standout
The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans
2009
Endothelial activation in monosodium urate monohydrate crystal‐induced inflammation. In vitro and in vivo studies on the roles of tumor necrosis factor α and interleukin‐1
1997
Death by TNF: a road to inflammation
2022
Tumor necrosis factor, cancer and anticancer therapy
2004
Pathogenesis and therapy of psoriasis
2007 StandoutNature
TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
2003
Apoptosis by Death Factor
1997 Standout
Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)
1995
Monoclonal anti‐TNFα Antibody as a Probe of Pathogenesis and Therapy of Rheumatoid Disease
1995
Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial
1999 Standout
Interleukin‐10 inhibition of the progression of established collagen‐induced arthritis
1996
TNF, Apoptosis and Autoimmunity: A Common Thread?
1998 StandoutNobel
Tumor Necrosis Factor-α Blockade: A Novel Therapy for Rheumatic Disease
2002
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
High levels of osteoprotegerin and soluble receptor activator of nuclear factor κB ligand in serum of rheumatoid arthritis patients and their normalization after anti–tumor necrosis factor α treatment
2002
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?
1996
Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis
2010
The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.
1998 Standout
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Autoantibodies in rheumatoid arthritis and their clinical significance.
2002
Cytokines in autoimmunity
1996
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions
2005
Collagen-Induced Arthritis in TNF Receptor-1-Deficient Mice: TNF Receptor-2 Can Modulate Arthritis in the Absence of TNF Receptor-1
2001
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis
1994
A proinflammatory role for IL-18 in rheumatoid arthritis
1999
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis
2000 Standout
Processing of tumour necrosis factor-α precursor by metalloproteinases
1994 Nature
Evidence that cytokines play a role in rheumatoid arthritis
2008
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Immunity, Inflammation, and Cancer
2010 Standout
Porphyromonas gingivalis Facilitates the Development and Progression of Destructive Arthritis through Its Unique Bacterial Peptidylarginine Deiminase (PAD)
2013
Periodontitis: from microbial immune subversion to systemic inflammation
2014 Standout
Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor ? monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
1998
Clinical trials of antibody therapy
2000
Porphyromonas gingivalis Peptidylarginine Deiminase, a Key Contributor in the Pathogenesis of Experimental Periodontal Disease and Experimental Arthritis
2014
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α‐enolase: Implications for autoimmunity in rheumatoid arthritis
2010
The type I interleukin‐1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF‐transgenic mice
1995
Inhibition of Immunoreactive Tumor Necrosis Factor- by a Chimeric Antibody in Patients Infected with Human Immunodeficiency Virus Type 1
1996
Identification of citrullinated rheumatoid arthritis‐specific epitopes in natural filaggrin relevant for antifilaggrin autoantibody detection by line immunoassay
2002
Anti-CCP antibodies: the past, the present and the future
2011
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
A microbial symbiosis factor prevents intestinal inflammatory disease
2008 StandoutNature
Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis
2014
Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis
2001
The Link Between Periodontal Disease and Rheumatoid Arthritis: An Updated Review
2014
Tumour necrosis factor and cancer
2009
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Tumor necrosis factor or tumor promoting factor?
2002
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
Anticytokine treatment of established type II collagen–induced arthritis in DBA/1 mice: A comparative study using anti‐TNFα, anti–IL‐1α/β, and IL‐1Ra
1996
Autoimmunity and Apoptosis
2001 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Cancer-related inflammation: Common themes and therapeutic opportunities
2011
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Rheumatoid Arthritis
1996
Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: implications for survival
2005
Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics
2008
Genetic insights into common pathways and complex relationships among immune-mediated diseases
2013
TNFRSF1A mutations and autoinflammatory syndromes
2000
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Immunological intervention reveals reciprocal roles for tumor necrosis factor-? and interleukin-10 in rheumatoid arthritis and systemic lupus erythematosus
1994
Osteoclasts are essential for TNF-α–mediated joint destruction
2002
Periodontitis in RA—the citrullinated enolase connection
2010
Autoimmunity and Anti-TNF-α Agents
2005
Etanercept Therapy in Rheumatoid Arthritis
1999
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
1999 StandoutScience
TNF-R1 Signaling: A Beautiful Pathway
2002 StandoutScience
Beneficial effects of tumour necrosis factor-alpha (TNF-α) blockade in rheumatoid arthritis (RA)
1995
Interleukin 6 plays a key role in the development of antigen-induced arthritis
1998
ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS
1996 Standout
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: A comparative study using anti-TNFα, anti-IL-1α/β and IL-1Ra
2008
Anti-TNFα Therapy of Rheumatoid Arthritis: What Have We Learned?
2001
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
2001
Effects of Thyroid Hormones on Bone and Mineral Metabolism
1990
Honokiol, a Natural Plant Product, Inhibits Inflammatory Signals and Alleviates Inflammatory Arthritis
2007 Standout
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Study of Etanercept, a Tumor Necrosis Factor-Alpha Inhibitor, in Recurrent Ovarian Cancer
2005
Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury
2003 StandoutNobel
Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation
1997 Standout
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Immunoregulatory role of interleukin 10 in rheumatoid arthritis.
1994
Osteoclasts are essential for TNF-α–mediated joint destruction
2002
The Biology of Chemokines and their Receptors
2000 Standout
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose
2007
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Long Term Safety of Infliximab
2000
Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis.
1994
Validation of the interleukin-10 knockout mouse model of colitis: antitumour necrosis factor-antibodies suppress the progression of colitis
2003
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein
1997
Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis.
1994
Works of P. Charles being referenced
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis.
1999
Serum levels of IL-6 and TNF-α correlate with clinicopathological features and patient survival in patients with prostate cancer
2004
Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis
2013
Antibodies to citrullinated α‐enolase peptide 1 are specific for rheumatoid arthritis and cross‐react with bacterial enolase
2008
Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor α: Findings in open-label and randomized placebo-controlled trials
2000
Anti-tumour necrosis factor specific antibody (infliximab) treatment provides insights into the pathophysiology of rheumatoid arthritis
1999
Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis
1994
Biological insights from clinical trials with anti-TNF therapy
1998
Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis
2009
Anaemia of chronic disease in rheumatoid arthritis: in vivo effects of tumour necrosis factor alpha blockade
1997
Interaction of HLA-DRB1*03 and smoking for the development of anti-Jo-1 antibodies in adult idiopathic inflammatory myopathies: a European-wide case study
2011
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α
1993
Multicenter validation of recombinant, natural and synthetic antigens used in a single multiparameter assay for the detection of specific anti-nuclear autoantibodies in connective tissue disorders.
1999
Calcium Metabolism Evaluated by 47Ca kinetics: Estimation of Dermal Calcium Loss
1983
Regulation of Cytokines, Cytokine Inhibitors, and Acute-Phase Proteins Following Anti-TNF-α Therapy in Rheumatoid Arthritis
1999