Standout Papers
- Treatment of marrow graft recipients with thymopentin. (1987)
- 1994 Consensus Conference on Acute GVHD Grading. (1995)
Citation Impact
Citing Papers
Eight-year experience with allogeneic stem cell transplantation for relapsed follicular lymphoma after nonmyeloablative conditioning with fludarabine, cyclophosphamide, and rituximab
2008
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
Transient adhesion of neutrophils to endothelium.
1989
The Sensation and Regulation of Interactions with the Extracellular Environment: The Cell Biology of Lymphocyte Adhesion Receptors
1990
HLA Match Likelihoods for Hematopoietic Stem-Cell Grafts in the U.S. Registry
2014 Standout
Enhanced responsiveness of human memory T cells to CD2 and CD3 receptor‐mediated activation
1989
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Kinetics and characterization of intercellular adhesion molecule-1 (ICAM-1) expression on keratinocytes in various inflammatory skin lesions and malignant cutaneous lymphomas
1989
Cell-cell adhesion mediated by CD8 and MHC class I molecules
1988 Nature
Treatment of relapse after allogeneic bone marrow transplantation
1996
Posaconazole or Fluconazole for Prophylaxis in Severe Graft-versus-Host Disease
2007 Standout
Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease
1995
Interaction between the CD45 antigen and phytohemagglutinin. Inhibitory effect on the lectininduced T cell proliferation by anti‐CD45 monoclonal antibody
1987
Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro.
1989
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
Placental Blood as a Source of Hematopoietic Stem Cells for Transplantation into Unrelated Recipients
1996
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
1992 StandoutNatureNobel
Molecular Events Mediating T Cell Activation
1990
Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal
1990 StandoutNobel
T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1
1989 Nature
Phorbol diesters increase the phosphorylation of the leukocyte common antigen CD45 in human T cells
1987
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
1997
Non‐endocrine late complications of bone marrow transplantation in childhood: part II
2002
Structural mechanisms of costimulation
2002
A second signal for T cell mitogenesis provided by monoclonal antibodies CD45 (T200)
1987
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
In vitro selection of RNA molecules that bind specific ligands
1990 StandoutNatureNobel
CD4: Collaborator in immune recognition and HIV infection
1990 StandoutNobel
The Leukocyte Integrins
1989
Outcomes among 562 Recipients of Placental-Blood Transplants from Unrelated Donors
1998 Standout
Neuroligin 1: A splice site-specific ligand for β-neurexins
1995 StandoutNobel
Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2)
1987 Nature
Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation
2010 Standout
Adhesion receptors of the immune system
1990 StandoutNature
Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
1988 StandoutNobel
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
Hematopoietic Stem-Cell Transplantation
2006 Standout
Signal transduction through cd4 receptors: stimulatory vs. inhibitory activity is regulated by cd4 proximity to the cd31t cell receptor
1988
Analysis of 462 Transplantations from Unrelated Donors Facilitated by the National Marrow Donor Program
1993
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
1991 StandoutNobel
Protective Conditioning for Acute Graft-versus-Host Disease
2005
Membrane Proteins Involved in Phagocyte Adherence to Endothelium
1990
Treatment of High-Risk Acute Leukemia with T-Cell–Depleted Stem Cells from Related Donors with One Fully Mismatched HLA Haplotype
1998
The Role of the CD28 Receptor During T Cell Responses to Antigen
1993
Outcomes of transplantation with matched-sibling and unrelateddonor bone marrow in children with leukaemia
1997
Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs
1990
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
1989
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution
1992 StandoutNobel
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti‐CD28 and anti‐CD2 monoclonal antibodies
1988
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Relation of an Interleukin-10 Promoter Polymorphism to Graft-versus-Host Disease and Survival after Hematopoietic-Cell Transplantation
2003
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site
1990 Standout
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.
1991
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.
1987
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
1988 StandoutNobel
Translating Stem and Progenitor Cell Biology to the Clinic: Barriers and Opportunities
2000 Science
HSV-TK Gene Transfer into Donor Lymphocytes for Control of Allogeneic Graft-Versus-Leukemia
1997 Science
Correlation of CD2 binding and functional properties of multimeric and monomeric lymphocyte function-associated antigen 3.
1989
HIV-1-Infected T Cells Show a Selective Signaling Defect After Perturbation of CD3/Antigen Receptor
1988 Science
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-kB-like response element
1991
LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes
1987
Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes.
1987
Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen
1987
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 StandoutScienceNobel
Treatment of severe autoimmune disease by stem-cell transplantation
2005 Nature
Shock and Tissue Injury Induced by Recombinant Human Cachectin
1986 StandoutScienceNobel
Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.
1990
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Naive and memory T cells show distinct pathways of lymphocyte recirculation.
1990
Ipilimumab plus Lenalidomide after Allogeneic and Autologous Stem Cell Transplantation for Patients with Lymphoid Malignancies
2017 StandoutNobel
Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants
2003
Augmentation of umbilical cord blood (UCB) transplantation with ex vivo–expanded UCB cells: results of a phase 1 trial using the AastromReplicell System
2003
Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor
1985 Nature
Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone
1987 StandoutNatureNobel
Stored placental blood for unrelated bone marrow reconstitution
1993
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.
1991
Structural variants of human T200 glycoprotein (leukocyte-common antigen).
1987
Cachectin: More Than a Tumor Necrosis Factor
1987 StandoutNobel
Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones
1986 Nature
Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells
2003
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Unrelated donor marrow transplantation in children
1995
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.
1988
Phase I Study of 131I-Anti-CD45 Antibody Plus Cyclophosphamide and Total Body Irradiation for Advanced Acute Leukemia and Myelodysplastic Syndrome
1999
The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation
2000
A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.
1989
Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex.
1989
A second subunit of CD8 is expressed in human T cells.
1988
Differential expression of the leucocyte-common antigen family
1988
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
The role of the L3T4 molecule in mitogen and antigen-activated signal transduction
1987
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.
1993
Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.
1985
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells.
1992 Nobel
The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.
1994 StandoutNobel
Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor.
1988
CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy
2001 StandoutNobel
Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion.
1987
BFR (bendamustine, fludarabine, and rituximab) allogeneic conditioning for chronic lymphocytic leukemia/lymphoma: reduced myelosuppression and GVHD
2014
Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins.
1989 StandoutNobel
Intercellular adhesion molecule 1 (ICAM-1) has a central role in cell-cell contact-mediated immune mechanisms.
1988
A subset of T cell receptors associated with L3T4 molecules mediates C6VL leukemia cell binding of its cognate retrovirus
1987 StandoutNobel
Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome
2004
The infusion of ex vivo activated and expanded CD4+CD25+ immune regulatory cells inhibits graft-versus-host disease lethality
2002
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
1989 StandoutNobel
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
Mature results of the M. D. Anderson Cancer Center risk-adapted transplantation strategy in mantle cell lymphoma
2009
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
HLA-matched related hematopoietic cell transplantation for chronic-phase CML using a targeted busulfan and cyclophosphamide preparative regimen
2003
Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.
1987
Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival
2002
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway.
1992
A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions.
1988
A synthetic peptide derived from the carboxy terminus of the laminin A chain represents a binding site for the alpha 3 beta 1 integrin
1992
Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1
1994 StandoutNobel
Works of P Beatty being referenced
The role of neutrophil membrane glycoprotein 150 (Gp-150) in neutrophil-mediated endothelial cell injury in vitro.
1985
Effect of HLA Compatibility on Engraftment of Bone Marrow Transplants in Patients with Leukemia or Lymphoma
1989
Treatment of severe Evans syndrome with an allogeneic cord blood transplant
1997
Treatment of adult acute lymphoblastic leukemia with allogeneic bone marrow transplantation. Multivariate analysis of factors affecting acute graft-versus-host disease, relapse, and relapse-free survival.
1991
Antibodies to Tp67 and Tp44 augment and sustain proliferative responses of activated T cells.
1985
Human monocyte adherence to cultured vascular endothelium: monoclonal antibody-defined mechanisms.
1985
Molecules mediating adhesion of T and B cells, monocytes and granulocytes to vascular endothelial cells.
1988
Marrow transplantation from unrelated donors for treatment of hematologic malignancies: effect of mismatching for one HLA locus
1993
Unrelated donor marrow transplantation therapy for chronic myelogenous leukemia: initial experience of the National Marrow Donor Program
1993
T lymphocyte adhesion to endothelial cells: mechanisms demonstrated by anti-LFA-1 monoclonal antibodies.
1986
Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial
1989
Computer program to predict likelihood of finding and HLA-matched donor: methodology, validation, and application.
1996
Marrow Transplantation for the Treatment of Chronic Myelogenous Leukemia
1986
Identification of a Cell Surface Protein Complex Mediating Phorbol Ester‐Induced Adhesion (Binding) among Human Mononuclear Leukocytes
1985
Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial
1989
1994 Consensus Conference on Acute GVHD Grading.
1995 Standout
What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants?
1990
Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens
1991
Prophylaxis of graft-versus-host disease by administration of the murine anti-IL-2 receptor antibody 2A3.
1991
Second marrow transplants in patients with leukemia who relapse after allogeneic marrow transplantation.
1988
Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]
1990
Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]
1990
Identification and functional characterization of two distinct epitopes on the human T cell surface protein Tp50.
1983
A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes.
1986
Comparison of morbidity and mortality after marrow transplantation from HLA-genotypically identical siblings and HLA-phenotypically identical unrelated donors.
1994
Long term effects and quality of life in children and adults after marrow transplantation.
1989
Definition of a common leukocyte cell-surface antigen (Lp95-150) associated with diverse cell-mediated immune functions.
1983
Antibodies to common leukocyte antigen p220 influence human T cell proliferation by modifying IL 2 receptor expression.
1985
Distinct patterns of transmembrane calcium flux and intracellular calcium mobilization after differentiation antigen cluster 2 (E rosette receptor) or 3 (T3) stimulation of human lymphocytes.
1986
Epitope mapping of the human surface suppressor/cytotoxic T cell molecule Tp32.
1984
Unrelated donor marrow transplantation therapy for chronic myelogenous leukemia: initial experience of the National Marrow Donor Program
1993