Citation Impact
Citing Papers
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Exploring the structural origins of cryptic sites on proteins
2018
MicroRNA-mediated gene regulation and the resilience of multicellular animals
2024 StandoutNobel
Efficient base editing with high precision in rabbits using YFE-BE4max
2020
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
2010
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Methods for evaluation of platelet function
2009 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Regulation of microRNA function in animals
2018 Standout
The Nuts and Bolts of Low-level Laser (Light) Therapy
2011 Standout
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
Targeting Oncogenic Mutant p53 for Cancer Therapy
2015
Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis
2015 Standout
A panel of eGFP reporters for single base editing by APOBEC-Cas9 editosome complexes
2019
Drugging the p53 pathway: understanding the route to clinical efficacy
2014
Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway
2012
Advances in metal-induced oxidative stress and human disease
2011 Standout
Exploring the role of receptor flexibility in structure-based drug discovery
2013
BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
2018
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
2018
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Molecular Dynamics Simulation for All
2018 Standout
Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion
2018
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Response variability to aspirin as assessed by the platelet function analyzer (PFA)-100
2007
D3R grand challenge 4: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies
2020
APR-246 reactivates mutant p53 by targeting cysteines 124 and 277
2018
Targeting apoptosis in cancer therapy
2020 Standout
Coronary flow reserve is impaired in patients with nonalcoholic fatty liver disease: Association with liver fibrosis
2010
New therapeutic strategies to treat human cancers expressing mutant p53 proteins
2018
Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics Simulations
2016
Broadening horizons: the role of ferroptosis in cancer
2021 Standout
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology
2016 StandoutNobel
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Intrinsic Nucleotide Preference of Diversifying Base Editors Guides Antibody Ex Vivo Affinity Maturation
2018
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
2019 Nature
Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
2020
Targeting mutant p53 for efficient cancer therapy
2017
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Signalling pathways linking integrins with cell cycle progression
2013
The APOBEC Protein Family: United by Structure, Divergent in Function
2016
Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing
2018 Standout
Structure-Based Analysis of Cryptic-Site Opening
2019
Trypanosoma cruzi Trans-Sialidase: Structural Features and Biological Implications
2013
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
Structural Basis for Target-Directed MicroRNA Degradation
2019
AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings
2021 Standout
Protein Ensemble Generation Through Variational Autoencoder Latent Space Sampling
2024 StandoutNobel
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
MagnEdit—interacting factors that recruit DNA-editing enzymes to single base targets
2020
Low level laser therapy for traumatic brain injury
2010
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective
2018 Standout
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression
2017 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
CRISPR-Cas in Streptococcus pyogenes
2019 StandoutNobel
Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations
2019 StandoutNobel
A fluorescent reporter for quantification and enrichment of DNA editing by APOBEC–Cas9 or cleavage by Cas9 in living cells
2018
Computer simulations explain mutation-induced effects on the DNA editing by adenine base editors
2020
Works of Özlem Demir being referenced
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53
2013
RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting
2016
APOBEC3B Nuclear Localization Requires Two Distinct N-Terminal Domain Surfaces
2018
Ensemble Docking in Drug Discovery
2018
Assessment of biochemical aspirin resistance at rest and immediately after exercise testing
2006
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
2016
The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches
2015
Both mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinases (ERK) 1/2 and phosphatidylinositide-3-OH kinase (PI3K)/Akt pathways regulate activation of E-twenty-six (ETS)-like transcription factor 1 (Elk-1) in U138 glioblastoma cells
2011
The Local Dinucleotide Preference of APOBEC3G Can Be Altered from 5′-CC to 5′-TC by a Single Amino Acid Substitution
2013
Ensemble-Based Computational Approach Discriminates Functional Activity of p53 Cancer and Rescue Mutants
2011
From Birth Till Death: Neurogenesis, Cell Cycle, and Neurodegeneration
2009
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B
2017
Modulation of Catalytic Function by Differential Plasticity of the Active Site: Case Study of Trypanosoma cruzi trans-Sialidase and Trypanosoma rangeli Sialidase
2009
Determinants of Oligonucleotide Selectivity of APOBEC3B
2018
Association of serum adiponectin levels and coronary flow reserve in women with normal coronary angiography
2009