Citation Impact
Citing Papers
Cardiac Hypertrophy: The Good, the Bad, and the Ugly
2003 Standout
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
2004 StandoutScience
Maintenance of Constitutive IκB Kinase Activity by Glycogen Synthase Kinase-3α/β in Pancreatic Cancer
2008
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Functional Cross-talk between β-Catenin and NFκB Signaling Pathways in Colonic Crypts of Mice in Response to Progastrin
2009
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria
2009
Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo
1996
MesP1 and MesP2 are essential for the development of cardiac mesoderm
2000
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Molecular Cloning of Transferrin Receptor 2
1999
Inflammation and metabolic disorders
2006 StandoutNature
Maintenance of functional equivalence during paralogous Hox gene evolution
2000 StandoutNatureNobel
Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis
2009
Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
1999
Akt Stimulates the Transactivation Potential of the RelA/p65 Subunit of NF-κB through Utilization of the IκB Kinase and Activation of the Mitogen-activated Protein Kinase p38
2001
Essential role of RelA Ser311 phosphorylation by PKC in NF- B transcriptional activation
2003
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
GSK-3α regulates production of Alzheimer's disease amyloid-β peptides
2003 Nature
Functional analysis of secreted and transmembrane proteins critical to mouse development
2001
Shared Principles in NF-κB Signaling
2008 Standout
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
2000
Balancing Acts
2004 Standout
Shaping the nuclear action of NF-κB
2004
Mutant β-spectrin 4 causes auditory and motor neuropathies in quivering mice
2001
An Iron Delivery Pathway Mediated by a Lipocalin
2002
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Conditional Protein Alleles Using Knockin Mice and a Chemical Inducer of Dimerization
2003
Gene-trap mutagenesis: past, present and beyond
2001
Tumor Necrosis Factor-α-induced IKK Phosphorylation of NF-κB p65 on Serine 536 Is Mediated through the TRAF2, TRAF5, and TAK1 Signaling Pathway
2003
NF-κB signaling pathways in mammalian and insect innate immunity
2001
Missing Pieces in the NF-κB Puzzle
2002 Standout
The Phosphorylation Status of Nuclear NF-ΚB Determines Its Association with CBP/p300 or HDAC-1
2002
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
A mouse model of juvenile hemochromatosis
2005
The vertebrate organizer: structure and molecules
1996
The Akt–GSK-3 signaling cascade in the actions of dopamine
2007
Identification of Modulators of TRAIL-Induced Apoptosis via RNAi-Based Phenotypic Screening
2003
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF‐κB and AP‐1 activation and IL‐8 and VEGF expression in human head and neck squamous cell carcinoma lines
2002
Immunity, Inflammation, and Cancer
2010 Standout
Opposite Role of Ras in Tumor Necrosis Factor-α-Induced Cell Cycle Regulation: Competition for Raf Kinase
2001
The immune response of Drosophila
2003 StandoutNatureNobel
Haemochromatosis
2018
Targeted Disruption of the ζPKC Gene Results in the Impairment of the NF-κB Pathway
2001
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Scara5 Is a Ferritin Receptor Mediating Non-Transferrin Iron Delivery
2009
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
NF-κB regulation in the immune system
2002 Standout
Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular Shuttle
2014
Crx, a Novel Otx-like Paired-Homeodomain Protein, Binds to and Transactivates Photoreceptor Cell-Specific Genes
1997
Requirement for Wnt3 in vertebrate axis formation
1999
A Red Carpet for Iron Metabolism
2017
Tumor necrosis factor signaling
2003 Standout
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Hepcidin, A New Iron Regulatory Peptide
2002
Genes that modify the hemochromatosis phenotype in mice
2000
Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
2005
Revealing the world of RNA interference
2004 StandoutNatureNobel
Signaling to NF-κB
2004 Standout
The Exocyst Complex in Health and Disease
2016
Signal transduction by tumor necrosis factor and its relatives
2001
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
A 5.5-kb Enhancer Is both Necessary and Sufficient for Regulation ofWnt-1Transcriptionin Vivo
1997
Glycogen Synthase Kinase-3β Haploinsufficiency Mimics the Behavioral and Molecular Effects of Lithium
2004
βIV Spectrins Are Essential for Membrane Stability and the Molecular Organization of Nodes of Ranvier
2004
Early Embryonic Lethality of H Ferritin Gene Deletion in Mice
2000
Global quantification of mammalian gene expression control
2011 StandoutNature
Mouse gastrulation: the formation of a mammalian body plan
1997
Toll-like receptor–mediated cytokine production is differentially regulated by glycogen synthase kinase 3
2005
Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo
1998 Nature
Specific Role of the Truncated βIV-Spectrin Σ6 in Sodium Channel Clustering at Axon Initial Segments and Nodes of Ranvier
2006 StandoutNobel
Anterior patterning in mouse
1998
The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression
2008
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development
2006
Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease
2011
Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity
2003 StandoutNobel
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes
2002
Mammalian Neural Stem Cells
2000 StandoutScience
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
2009
Mouse Otx2 functions in the formation and patterning of rostral head.
1995 Standout
The Drosophila Atypical Protein Kinase C-Ref(2)P Complex Constitutes a Conserved Module for Signaling in the Toll Pathway
2002
Neural stem cells: From fly to vertebrates
1998
IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy
2003
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Regulation of Intracellular Iron Metabolism in Human Erythroid Precursors by Internalized Extracellular Ferritin
1999
Patterning the Vertebrate Neuraxis
1996 Science
Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
1999
Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain
1998
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Two distinctive pathways for recruitment of naïve and primed IgM+B cells to the gut lamina propria
2005 StandoutNobel
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
2005
Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis
2004 StandoutNobel
Conserved regulation of the lymphocyte-specific expression oflckin the Fugu and mammals
2002 StandoutNobel
Neural Science
2000 StandoutNobel
Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression
1998 StandoutNobel
Direct interorganellar transfer of iron from endosome to mitochondrion
2007
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Cis-acting elements conserved between mouse and pufferfish Otx2 genes govern the expression in mesencephalic neural crest cells
1997
TAB2 Is Essential for Prevention of Apoptosis in Fetal Liver but Not for Interleukin-1 Signaling
2003
Macrophages and iron trafficking at the birth and death of red cells
2015
Glycogen Synthase Kinase 3 Phosphorylates Hypoxia-Inducible Factor 1α and Mediates Its Destabilization in a VHL-Independent Manner
2007
Emx1 and Emx2 functions in development of dorsal telencephalon
1997
Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function
1997
The molecular defect in hypotransferrinemic mice
2000
Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice
2001 Science
Molecular Targets of Lithium Action
2001
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
2004
Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate
1998 StandoutNobel
Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2)
2005
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
2002
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network
2008
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
The Evolution of Controlled Multitasked Gene Networks: The Role of Introns and Other Noncoding RNAs in the Development of Complex Organisms
2001
Regulation of Intracellular Iron Metabolism in Human Erythroid Precursors by Internalized Extracellular Ferritin
1999
Forebrain and midbrain regions are deleted in Otx2−/− mutants due to a defective anterior neuroectoderm specification during gastrulation
1995
Genetic control of brain morphogenesis through Otx gene dosage requirement
1997
βIVΣ1 spectrin stabilizes the nodes of Ranvier and axon initial segments
2004
Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning
1998
βIV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier
2002
Works of Ou Jin being referenced
A New Spectrin, βIV, Has a Major Truncated Isoform That Associates with Promyelocytic Leukemia Protein Nuclear Bodies and the Nuclear Matrix
2001
Transferrin receptor is necessary for development of erythrocytes and the nervous system
1999
Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif
1998
Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
2000 Nature
A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice
2005
A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain
1996
Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants
1994