Citation Impact
Citing Papers
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MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness
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Vesicular stomatitis virus transcription inhibited by purified MxA protein
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Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic
1991 Nature
Interferon-α activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes
2002
TFIIH Transcription Factor, a Target for the Rift Valley Hemorrhagic Fever Virus
2004
Human MxB Protein, an Interferon-α-inducible GTPase, Contains a Nuclear Targeting Signal and Is Localized in the Heterochromatin Region beneath the Nuclear Envelope
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Inducible Gene Targeting in Mice
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Type I Interferons Potently Enhance Humoral Immunity and Can Promote Isotype Switching by Stimulating Dendritic Cells In Vivo
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ISG20, a New Interferon-induced RNase Specific for Single-stranded RNA, Defines an Alternative Antiviral Pathway against RNA Genomic Viruses
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Interferon signalling network in innate defence
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Partial Inhibition of Vesicular Stomatitis Virus by the Interferon-Induced Human 9-27 Protein
1996
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis
1991 Nature
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A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Rift Valley Fever Virus NSs Protein Promotes Post-Transcriptional Downregulation of Protein Kinase PKR and Inhibits eIF2α Phosphorylation
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Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency
2003
In vitro and in vivo studies of the Interferon-alpha action on distinct Orthobunyavirus
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Revealing the world of RNA interference
2004 StandoutNatureNobel
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
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A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting
1990
Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics
2006 StandoutNobel
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins
1990 Nature
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
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Influenza
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Reactivation of Latent Human Cytomegalovirus by Allogeneic Stimulation of Blood Cells from Healthy Donors
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CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
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2004
Impaired Antiviral Response in Human Hepatoma Cells
1999
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Extrathymic positive selection of αβ T-cell precursors in nude mice
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Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees
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The synaptic vesicle cycle: a cascade of protein–protein interactions
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Effect of interferon-α and cell differentiation on Puumala virus infection in human monocyte/macrophages
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The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus
2009
Interferon-Induced Proteins and the Antiviral State
1990
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
2001 Standout
Dynamin is a GTPase stimulated to high levels of activity by microtubules
1992 Nature
Interferon Action in Triply Deficient Mice Reveals the Existence of Alternative Antiviral Pathways
1999
Interferons, Mx Genes, and Resistance to Influenza Virus
1995
Reassortment and Mutation of the Avian Influenza Virus Polymerase PA Subunit Overcome Species Barriers
2011 StandoutNobel
Viperin, MTAP44, and Protein Kinase R Contribute to the Interferon-Induced Inhibition of Bunyamwera Orthobunyavirus Replication
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Lambda Interferon Inhibits Hepatitis B and C Virus Replication
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Liver-Directed Gamma Interferon Gene Delivery in Chronic Hepatitis C
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2002 StandoutNobel
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2006
A functional GTP-binding motif is necessary for antiviral activity of Mx proteins
1993
Flying Under the Radar: The Immunobiology of Hepatitis C
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T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes
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Functional classification of interferon-stimulated genes identified using microarrays
2001
Linkage of prion protein and scrapie incubation time genes
1986 StandoutNobel
Effector Genes of Interferon Action Against Hepatitis C Virus
2003
Western blot profiles, lymph node ultrastructure and viral expression in HIV-infected patients: a correlative study.
1987
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1986 StandoutNobel
Interferon-induced MxA Protein.
1995
Combination of a Hepatitis C Virus NS3-NS4A Protease Inhibitor and Alpha Interferon Synergistically Inhibits Viral RNA Replication and Facilitates Viral RNA Clearance in Replicon Cells
2004
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
Effects of mutant rat dynamin on endocytosis
1993
Genome organization and transactivation of the human immunodeficiency virus type 2
1987 StandoutNatureNobel
Comparative Analysis of Anti-Hepatitis C Virus Activity and Gene Expression Mediated by Alpha, Beta, and Gamma Interferons
2002
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products
1988
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease
2002
Intrahepatic Gene Expression during Chronic Hepatitis C Virus Infection in Chimpanzees
2004
Cytopathic and Noncytopathic Interferon Responses in Cells Expressing Hepatitis C Virus Subgenomic Replicons
2003
Regulation of immune response to tumor antigen: interference with syngeneic tumor immunity by anti-IA alloantisera.
1979 StandoutNobel
The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection
1980
Plasmacytoid predendritic cells initiate psoriasis through interferon-α production
2005
Hepatitis C virus RNA replication is resistant to tumour necrosis factor-α
2003
Isolation of a New Human Retrovirus from West African Patients with AIDS
1986 StandoutScienceNobel
Differential expression and regulation of multiple dynamins.
1994 StandoutNobel
Functional Role of Type I and Type II Interferons in Antiviral Defense
1994 StandoutScience
Viral RNA Silencing Suppression: The Enigma of Bunyavirus NSs Proteins
2016
Molecular Determinants of Adaptation of Highly Pathogenic Avian Influenza H7N7 Viruses to Efficient Replication in the Human Host
2009
Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB
2004
Viruses and Interferons
2001
Bunyaviruses and the Type I Interferon System
2009
Hepatitis C virus NS5A protein interacts with 2′,5′-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner
2004
Antiviral Effect and Virus-Host Interactions in Response to Alpha Interferon, Gamma Interferon, Poly(I)-Poly(C), Tumor Necrosis Factor Alpha, and Ribavirin in Hepatitis C Virus Subgenomic Replicons
2002
Antiviral Actions of Interferons
2001 Standout
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The Epidemiology of AIDS: Current Status and Future Prospects
1985 Science
MxA-dependent inhibition of measles virus glycoprotein synthesis in a stably transfected human monocytic cell line
1993
Highly Permissive Cell Lines for Subgenomic and Genomic Hepatitis C Virus RNA Replication
2002 StandoutNobel
Genetic diversity and evolution of hepatitis C virus – 15 years on
2004
Interference of hepatitis C virus RNA replication by short interfering RNAs
2003
Creation of a Nonspreading Rift Valley Fever Virus
2011
Replication of HIV-1 in Dendritic Cell-Derived Syncytia at the Mucosal Surface of the Adenoid
1996 StandoutScienceNobel
Dynamin: A microtubule-associated GTP-binding protein
1991
Requirement of the N-Terminal Region of Orthobunyavirus Nonstructural Protein NSm for Virus Assembly and Morphogenesis
2006
Cross-Genotype Immunity to Hepatitis C Virus
2004
Stealth and Cunning: Hepatitis B and Hepatitis C Viruses
2005
Real time quantitative PCR.
1996 Standout
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.
1995
Differential antigen burden modulates the gamma interferon but not the immunoglobulin response in mice that vary in susceptibility to Sendai virus pneumonia
1995 StandoutNobel
Identification of Three Interferon-Inducible Cellular Enzymes That Inhibit the Replication of Hepatitis C Virus
2007
Host Restriction of Avian Influenza Viruses at the Level of the Ribonucleoproteins
2008
Interferon response element of the human gene 6-16.
1988
Structure of mouse Mx1 protein. Molecular assembly and GTP-dependent conformational change
1993
Hepatitis C virus NS5A: tales of a promiscuous protein
2004
Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/Beta Interferon
2002
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20
2018 StandoutNobel
NSs Protein of Rift Valley Fever Virus Induces the Specific Degradation of the Double-Stranded RNA-Dependent Protein Kinase
2009
A genetic analysis of natural resistance to nonsyngeneic cells: The role of H-2
1984
Predominant and developmentally regulated expression of dynamin in neurons
1991
The Role of T Cell Growth Stimulating Factors in T Cell Triggering
1980
The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains.
1992
Interleukin-1 Inhibits Hepatitis C Virus Subgenomic RNA Replication by Activation of Extracellular Regulated Kinase Pathway
2003
Tumor Necrosis Factor Alpha Exerts Powerful Anti-Influenza Virus Effects in Lung Epithelial Cells
2002
Noncytolytic Control of Viral Infections by the Innate and Adaptive ImmuneResponse
2001
Dendritic Cells Exposed to Human Immunodeficiency Virus Type-1 Transmit a Vigorous Cytopathic Infection to CD4 + T Cells
1992 StandoutScienceNobel
Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase
2011
Cell-Mediated Immunity and the Outcome of Hepatitis C Virus Infection
2004
Host and Viral Determinants of Mx2 Antiretroviral Activity
2014
Virulence and Genetic Compatibility of Polymerase Reassortant Viruses Derived from the Pandemic (H1N1) 2009 Influenza Virus and Circulating Influenza A Viruses
2011
Pathogenesis and Immune Response of Crimean-Congo Hemorrhagic Fever Virus in a STAT-1 Knockout Mouse Model
2010
Interferon Regulatory Factor 1 Is Required for Mouse Gbp Gene Activation by Gamma Interferon
1995
Viruses in the Anopheles A, Anopheles B, and Tete Serogroups in the Orthobunyavirus Genus (Family Bunyaviridae ) Do Not Encode an NSs Protein
2009
The Ebola virus VP35 protein functions as a type I IFN antagonist
2000
Intra-Blood–Brain-Barrier Synthesis of HTLV-III-Specific IgG in Patients with Neurologic Symptoms Associated with AIDS or AIDS-Related Complex
1985
Activation of PKR by Bunyamwera Virus Is Independent of the Viral Interferon Antagonist NSs
2003
Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures
2000
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Otto Haller being referenced
Influenza Virus Resistance of Wild Mice: Wild-Type and Mutant Mx Alleles Occur at Comparable Frequencies
1987
Interferon-Induced Rat Mx Proteins Confer Resistance to Rift Valley Fever Virus and Other Arthropod-Borne Viruses
2001
Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity
2010
Inverse Interference: How Viruses Fight the Interferon System
2004
Interferon-induced Mx proteins in antiviral host defense
2007
Mx1 but Not MxA Confers Resistance against Tick-Borne Dhori Virus in Mice
1995
Self-assembly of Human MxA GTPase into Highly Ordered Dynamin-like Oligomers
2002
Interferon-induced guanylate-binding proteins: Mapping murine Gbp-1 locus to chromosome 3
1985
The antiviral effect of interferon-beta against SARS-Coronavirus is not mediated by MxA protein
2004
Missorting of LaCrosse Virus Nucleocapsid Protein by the Interferon‐Induced MxA GTPase Involves Smooth ER Membranes
2004
GTP-bound Human MxA Protein Interacts with the Nucleocapsids of Thogoto Virus (Orthomyxoviridae)
1999
Type I interferon inhibits Crimean-Congo hemorrhagic fever virus in human target cells
2005
Protective role of interferon-induced Mx GTPases against influenza viruses
2009
Characterization and Expression of the Mx1 Gene in Wild Mouse Species
1998
The interferon response circuit: Induction and suppression by pathogenic viruses
2005
Interferon-γ inhibits replication of subgenomic and genomic hepatitis C virus RNAs
2002
Mx genes show weaker primary response to virus than other interferon-regulated genes
1992
Mx1 sensitivity: Batken virus is an orthomyxovirus closely related to Dhori virus.
1997
Inhibition of influenza C viruses by human MxA protein
2000
Human Cytomegalovirus Immediate Early and Late Transcripts Are Expressed in All Major Leukocyte Populations In Vivo
1995
Structural basis of oligomerization in the stalk region of dynamin-like MxA
2010 Nature
Interferon, Mx, and viral countermeasures
2007
MxA Gene Expression after Live Virus Vaccination: A Sensitive Marker for Endogenous Type I Interferon
1994
Mx Transgenic Mice — Animal Models of Health
1996
Mx proteins: mediators of innate resistance to RNA viruses
1998
Inhibition of Coxsackievirus B4 Replication in Stably Transfected Cells Expressing Human MxA Protein
2001
Interferon‐Induced Mx Proteins: Dynamin‐Like GTPases with Antiviral Activity
2002
Inhibition of RNA Polymerase II Phosphorylation by a Viral Interferon Antagonist
2004
Evolution-Guided Identification of Antiviral Specificity Determinants in the Broadly Acting Interferon-Induced Innate Immunity Factor MxA
2012
A Classical Bipartite Nuclear Localization Signal on Thogoto and Influenza A Virus Nucleoproteins
1998
Polyclonal and monoclonal antibodies to the interferon-inducible protein Mx of influenza virus-resistant mice.
1985
Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity
1997
Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21
1988
Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids
1999
Host gene influences sensitivity to interferon action selectively for influenza virus
1980 Nature
cDNA Structures and Regulation of Two Interferon-Induced Human Mx Proteins
1989
Inhibition of influenza viral mRNA synthesis in cells expressing the interferon-induced Mx gene product
1985
Interferon-regulated influenza virus resistance gene Mx is localized on mouse chromosome 16
1986
Activity of rat Mx proteins against a rhabdovirus
1990
Antiviral state against influenza virus neutralized by microinjection of antibodies to interferon-induced Mx proteins.
1988
Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus
1995
Inborn Resistance of Mice to Orthomyxoviruses
1981
Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPase
2008
Role of non-conventional natural killer cells in resistance against syngeneic tumour cells in vivo
1977 Nature
Interferon-regulated Mx genes are not responsive to interleukin-1, tumor necrosis factor, and other cytokines
1991
Interferon-induced human protein with homology to protein Mx of influenza virus-resistant mice.
1985
Interferon-α inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway
2001
Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts
1977
Athymic (nude) mice express gene for myxovirus resistance
1974 Nature
Antibodies to HTLV-III in Swiss Patients with AIDS and Pre-AIDS and in Groups at Risk for AIDS
1985
Hantaan Virus Infection Causes an Acute Neurological Disease That Is Fatal in Adult Laboratory Mice
2002
Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation.
1988
A family of interferon-induced Mx-related mRNAs encodes cytoplasmic and nuclear proteins in rat cells
1988
MxA GTPase Blocks Reporter Gene Expression of Reconstituted Thogoto Virus Ribonucleoprotein Complexes
2000
Interferon induces a unique protein in mouse cells bearing a gene for resistance to influenza virus.
1983
Genetic control of interferon action: Mouse strain distribution and inheritance of an induced protein with guanylate-binding property
1984
Inhibition of Beta Interferon Induction by Severe Acute Respiratory Syndrome Coronavirus Suggests a Two-Step Model for Activation of Interferon Regulatory Factor 3
2005
Inborn resistance of mice to myxoviruses: macrophages express phenotype in vitro.
1978
Transcriptional activation of the mouse Mx gene by type I interferon.
1986
Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen.
1990
Influenza Virus-Susceptible Mice Carry Mx Genes with a Large Deletion or a Nonsense Mutation
1988
Human MxA Protein Protects Mice Lacking a Functional Alpha/Beta Interferon System against La Crosse Virus and Other Lethal Viral Infections
1999
Mx-dependent resistance to influenza viruses is induced by mouse interferons α and β but not γ
1984
Inhibition of bunyaviruses, phleboviruses, and hantaviruses by human MxA protein
1996
Enhanced virus resistance of transgenic mice expressing the human MxA protein
1995
Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes
2002
Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1
1995
Interferon-induced Mx protein: a mediator of cellular resistance to influenza virus.
1987
Genetic Evidence for an Interferon-Antagonistic Function of Rift Valley Fever Virus Nonstructural Protein NSs
2001
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
2007
Mx protein: Constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus
1986
Functional L polymerase of La Crosse virus allows in vivo reconstitution of recombinant nucleocapsids
2003
Adaptive Mutations Resulting in Enhanced Polymerase Activity Contribute to High Virulence of Influenza A Virus in Mice
2009
NSs Protein of Rift Valley Fever Virus Blocks Interferon Production by Inhibiting Host Gene Transcription
2004
Human MxA Protein Inhibits the Replication of Crimean-Congo Hemorrhagic Fever Virus
2004
Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein
1990
Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle
1992
The Nucleoprotein of Newly Emerged H7N9 Influenza A Virus Harbors a Unique Motif Conferring Resistance to Antiviral Human MxA
2014
Viral suppression of the interferon system
2007
Identification of the Murine Mx2 Gene: Interferon-Induced Expression of the Mx2 Protein from the Feral Mouse Gene Confers Resistance to Vesicular Stomatitis Virus
1999
A functional comparison of tumor cell killing by activated macrophages and natural killer cells
1979
A Monomeric GTPase-Negative MxA Mutant with Antiviral Activity
2000
Interferon-dependent Genetic Resistance to Influenza Virus in Mice: Virus Replication in Macrophages is Inhibited at an Early Step
1980
cDNA structures and regulation of two interferon-induced human Mx proteins.
1989
Antibody to mouse interferon alpha/beta abrogates resistance to the multiplication of Friend erythroleukemia cells in the livers of allogeneic mice.
1988
Genetic Resistance to Influenza Virus in Wild Mice
1986
Interferon-induced protein Mx accumulates in nuclei of mouse cells expressing resistance to influenza viruses
1985
Transcriptional Activation of the Mouse Mx Gene by Type I Interferon
1986
Interferon-Induced Human Protein with Homology to Protein Mx of Influenza Virus-Resistant Mice
1985