Citation Impact
Citing Papers
Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites
2007
Bardet–Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly
2004
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
STAR: ultrafast universal RNA-seq aligner
2012 Standout
A role for the inositol kinase Ipk1 in ciliary beating and length maintenance
2007
Unusual DNA Structures Associated With Germline Genetic Activity in Caenorhabditis elegans
2006 StandoutNobel
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
2008 StandoutScienceNobel
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
The Gene Ontology of eukaryotic cilia and flagella
2017
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
Bardet-Biedl Syndrome-associated Small GTPase ARL6 (BBS3) Functions at or near the Ciliary Gate and Modulates Wnt Signaling
2010
RPGR-ORF15, Which Is Mutated in Retinitis Pigmentosa, Associates with SMC1, SMC3, and Microtubule Transport Proteins
2005
Proximal events in Wnt signal transduction
2009
The Gene Ontology Resource: 20 years and still GOing strong
2018 Standout
Relative Unidirectional Translation in an Artificial Molecular Assembly Fueled by Light
2013 StandoutNobel
The Primary Cilium as a Complex Signaling Center
2009
IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy
2007
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8
2008
Role of Primary Cilia in the Pathogenesis of Polycystic Kidney Disease
2007
PDGFRαα Signaling Is Regulated through the Primary Cilium in Fibroblasts
2005
Piecing together a ciliome
2006
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome
2006
Forces in Tissue Morphogenesis and Patterning
2013 Standout
Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
2024 StandoutNobel
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Chemosensation in C. elegans
2006
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
2013 StandoutNobel
The nonmotile ciliopathies
2009
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence
2012 StandoutNatureNobel
Assembly of primary cilia
2008
Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics
2008
STRING v10: protein–protein interaction networks, integrated over the tree of life
2014 Standout
Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse
2004
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Ciliary Targeting of Olfactory CNG Channels Requires the CNGB1b Subunit and the Kinesin-2 Motor Protein, KIF17
2006
The Graded Response to Sonic Hedgehog Depends on Cilia Architecture
2007
The Human Transcription Factors
2018 Standout
C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
2009 StandoutNobel
Dissection of epistasis in oligogenic Bardet–Biedl syndrome
2005 Nature
Bardet–Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function
2006
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
2008
Polycystins and mechanosensation in renal and nodal cilia
2004
Kinesin superfamily motor proteins and intracellular transport
2009 Standout
Cilia Proteins Control Cerebellar Morphogenesis by Promoting Expansion of the Granule Progenitor Pool
2007
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
2011
Decoding Cilia Function
2004
Mechanically Activated Ion Channels
2015 StandoutNobel
BBS8 is rarely mutated in a cohort of 128 Bardet–Biedl syndrome families
2005
The Vertebrate Primary Cilium in Development, Homeostasis, and Disease
2009
C. elegans dauer formation and the molecular basis of plasticity
2008
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
2013
Polygenic control of Caenorhabditis elegans fat storage
2006 StandoutNobel
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression
2004
Retinitis pigmentosa
2006 Standout
Cilia: Tuning in to the Cell's Antenna
2006
Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component
2009
Mechanotransduction and auditory transduction in Drosophila
2007
Asymmetric Inheritance of Centrosome-Associated Primary Cilium Membrane Directs Ciliogenesis after Cell Division
2013
A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling
2009
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Pitfalls of homozygosity mapping: an extended consanguineous Bardet–Biedl syndrome family with two mutant genes (BBS2, BBS10), three mutations, but no triallelism
2006
HISAT: a fast spliced aligner with low memory requirements
2015 Standout
Stages of ciliogenesis and regulation of ciliary length
2011
A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain
2011
Dauer
2007
Transcriptional control of genes involved in ciliogenesis: a first step in making cilia
2010
Survey of the year 2003 commercial optical biosensor literature
2004
A survey of the year 2002 commercial optical biosensor literature
2003
A TRPV Channel Modulates C. elegans Neurosecretion, Larval Starvation Survival, and Adult Lifespan
2008
A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
2007 Standout
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development
2009
Formation of Primary Cilia in the Renal Epithelium Is Regulated by the von Hippel-Lindau Tumor Suppressor Protein
2006
The oligogenic properties of Bardet-Biedl syndrome
2004
Comparative Genomics and Gene Expression Analysis Identifies BBS9, a New Bardet-Biedl Syndrome Gene
2005
Retrograde Intraflagellar Transport Mutants Identify Complex A Proteins With Multiple Genetic Interactions inChlamydomonas reinhardtii
2009
The evolution of land plant cilia
2012
Trafficking in and to the primary cilium
2012
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia
2013
Comparative Genomic Analysis Identifies an ADP-Ribosylation Factor–like Gene as the Cause of Bardet-Biedl Syndrome (BBS3)
2004
Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia
2009
Mkks-null mice have a phenotype resembling Bardet–Biedl syndrome
2005
Wnt Signaling in Polycystic Kidney Disease
2007
Cell regulation: determined to signal discrete cooperation
2009
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
2009 StandoutNobel
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
Intraflagellar Transport and Cilium-Based Signaling
2006
The role of primary cilia in neuronal function
2010
Neurosensory mechanotransduction
2008 StandoutNobel
PhyloGene server for identification and visualization of co-evolving proteins using normalized phylogenetic profiles
2015 StandoutNobel
The primary cilium: a signalling centre during vertebrate development
2010 Standout
CTCF: Master Weaver of the Genome
2009 Standout
Evolution of intraflagellar transport from coated vesicles and autogenous origin of the eukaryotic cilium
2006
The Ciliopathies: An Emerging Class of Human Genetic Disorders
2006
Design and Synthesis of Nonequilibrium Systems
2015 StandoutNobel
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
2013 Standout
Cryo-electron tomography reveals conserved features of doublet microtubules in flagella
2011
Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling
2012
Bbs2 -null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin
2004
Serpin Structure, Mechanism, and Function
2002 Standout
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Absence of primary cilia in cell cycle‐arrested human breast cancer cells
2013
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
Cystic diseases of the kidney: ciliary dysfunction and cystogenic mechanisms
2010
ConditionalKif3aablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis
2007
The Rilp-like proteins Rilpl1 and Rilpl2 regulate ciliary membrane content
2012
Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion
2009
Genetics of obesity
2006
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis
2005
Switching on cilia: transcriptional networks regulating ciliogenesis
2014
Coordinated genomic control of ciliogenesis and cell movement by RFX2
2014
RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1
2007
Smoothened Signal Transduction Is Promoted by G Protein-Coupled Receptor Kinase 2
2006 StandoutNobel
Principles of planar polarity in animal development
2011
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
Robust excitons inhabit soft supramolecular nanotubes
2014 StandoutNobel
Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins
2011
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways fromDrosophilato vertebrates
2005
Bardet–Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
2008
Artificial Molecular Machines
2015 Standout
Cep164, a novel centriole appendage protein required for primary cilium formation
2007
Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole–cilium interface and facilitates proper cilium formation and function
2014 StandoutNobel
Syntheses and Dynamics of Donor−Acceptor [2]Catenanes in Water
2010 StandoutNobel
Protein Sorting at thetrans-Golgi Network
2014 Nobel
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Analysis of xbx genes in C. elegans
2005 StandoutNobel
Deciphering the Structure and Function of Als2cr4 in the Mouse Retina
2010
Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM)
2011
Homozygosity mapping with SNP arrays identifiesTRIM32, an E3 ubiquitin ligase, as a Bardet–Biedl syndrome gene (BBS11)
2006
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney
2004
Works of Oliver E. Blacque being referenced
Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors
2006
Identification of ciliary and ciliopathy genes in Caenorhabditis elegansthrough comparative genomics
2006
Basal body dysfunction is a likely cause of pleiotropic Bardet–Biedl syndrome
2003 Nature
Bardet-Biedl syndrome: an emerging pathomechanism of intracellular transport
2006
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport
2004
Evidence for a Direct Interaction between the Tumor Suppressor Serpin, Maspin, and Types I and III Collagen
2002
Functional Genomics of the Cilium, a Sensory Organelle
2005
Functional coordination of intraflagellar transport motors
2005 Nature
Endocytosis Genes Facilitate Protein and Membrane Transport in C. elegans Sensory Cilia
2012
Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
2010
MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis
2011
Caenorhabditis elegansDYF-2, an Orthologue of Human WDR19, Is a Component of the Intraflagellar Transport Machinery in Sensory Cilia
2006
Transmembrane protein OSTA-1 shapes sensory cilia morphology via regulation of intracellular membrane trafficking in C. elegans
2013
Intraflagellar transport: from molecular characterisation to mechanism
2007
The WD Repeat-containing Protein IFTA-1 Is Required for Retrograde Intraflagellar Transport
2006
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome
2004
Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle
2012
Sensory Ciliogenesis inCaenorhabditis elegans: Assignment of IFT Components into Distinct Modules Based on Transport and Phenotypic Profiles
2007
Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins
2009
The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization
2012
The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport
2010