Standout Papers
Citation Impact
Citing Papers
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines
2007 StandoutNobel
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
2009 StandoutScience
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells
2009
iPS Cells Reprogrammed From Human Mesenchymal-Like Stem/Progenitor Cells of Dental Tissue Origin
2009
Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence
2010
Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease
2006
Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
2008
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Developing dopaminergic cell therapy for Parkinson's disease—give up or move forward?
2013
Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway
2009
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
2009 Standout
iPS Cells Can Support Full-Term Development of Tetraploid Blastocyst-Complemented Embryos
2009
Generation of Human Melanocytes from Induced Pluripotent Stem Cells
2011 StandoutNobel
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises
2011
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
2010
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
2011
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
Forces in Tissue Morphogenesis and Patterning
2013 Standout
Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
2009
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Induced Pluripotent Stem Cells Meet Genome Editing
2016
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
2009 Nature
Modeling familial Alzheimer's disease with induced pluripotent stem cells
2011 StandoutNobel
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
2016 Nature
Reprogramming of Somatic Cells to Pluripotency
2010 StandoutNobel
Transient expression of the conserved zinc finger gene INSM1 in progenitors and nascent neurons throughout embryonic and adult neurogenesis
2008
Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
2008
Constructing and Deconstructing Stem Cell Models of Neurological Disease
2011
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
A nonviral minicircle vector for deriving human iPS cells
2010
Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
2009
LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
2011
Transcription Factor-Induced Lineage Selection of Stem-Cell-Derived Neural Progenitor Cells
2011
Reprogramming Cellular Identity for Regenerative Medicine
2012
Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
2009
Induced pluripotency: history, mechanisms, and applications
2010
Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process?
2011 StandoutNobel
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
2011 Nature
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
2011
Insulinoma-Associated 1 Has a Panneurogenic Role and Promotes the Generation and Expansion of Basal Progenitors in the Developing Mouse Neocortex
2008 StandoutNobel
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Genetic engineering of human pluripotent cells using TALE nucleases
2011
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
2015 Nature
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
2013 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues
2010
Parkinson's disease
2015 Standout
Blocking Soluble Tumor Necrosis Factor Signaling with Dominant-Negative Tumor Necrosis Factor Inhibitor Attenuates Loss of Dopaminergic Neurons in Models of Parkinson's Disease
2006
Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome
2010
Current progress and prospects of induced pluripotent stem cells
2009
Parkinson's Disease: Gene Therapies
2012
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease
2011 Nature
How widespread is adult neurogenesis in mammals?
2007
Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
2011
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
2009 StandoutNobel
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
2008
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
Ekiden to iPS Cells
2009 StandoutNobel
A Fresh Look at iPS Cells
2009 StandoutNobel
Neuroinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention
2007
Transplanted dopaminergic neurons develop PD pathologic changes: A second case report
2008
Efficient induction of functional neurons from adult human fibroblasts
2011
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
2009
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease
2011
Induced pluripotent stem cells: a new revolution for clinical neurology?
2011
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
2008
Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1β in the substantia nigra
2006
Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
2009
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Progress toward the clinical application of patient-specific pluripotent stem cells
2010
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
2010
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
2009 Nature
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
2010 Nature
Modeling Development and Disease with Organoids
2016 Standout
A functionally characterized test set of human induced pluripotent stem cells
2011
Stem cells for the treatment of neurological disorders
2006 Nature
From genes to function: the next challenge to understanding multiple sclerosis
2009
Genome-editing Technologies for Gene and Cell Therapy
2016
Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
2009 StandoutNatureNobel
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
2013 StandoutNobel
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian Rats
2007
iPSC Disease Modeling
2012 Science
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
2008
Dental Pulp Cells for Induced Pluripotent Stem Cell Banking
2010 StandoutNobel
Specific MicroRNAs Modulate Embryonic Stem Cell–Derived Neurogenesis
2005
Neuroimmunological Processes in Parkinson’s Disease and their Relation to α-Synuclein: Microglia as the Referee between Neuronal Processes and Peripheral Immunity
2013
Efficient In Vitro Labeling of Human Neural Precursor Cells with Superparamagnetic Iron Oxide Particles: Relevance for In Vivo Cell Tracking
2007
Generation of Transgene-Free Lung Disease-Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette
2010
Collective cell migration in development
2009
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Cell Therapy for Parkinson's Disease: What Next?
2013
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
Adenoviral Gene Delivery Can Reprogram Human Fibroblasts to Induced Pluripotent Stem Cells
2009
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
2009
Direct reprogramming of mouse fibroblasts to neural progenitors
2011
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
2010 StandoutNobel
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4
2009
Excision of Reprogramming Transgenes Improves the Differentiation Potential of iPS Cells Generated with a Single Excisable Vector
2009
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
New strategies to generate induced pluripotent stem cells
2009
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
2010
Works of Oliver Cooper being referenced
The migration of paraxial and lateral plate mesoderm cells emerging from the late primitive streak is controlled by different Wnt signals
2008
Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease.
2004
LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction
2013
Intrastriatal Transforming Growth Factor α Delivery to a Model of Parkinson's Disease Induces Proliferation and Migration of Endogenous Adult Neural Progenitor Cells without Differentiation into Dopaminergic Neurons
2004
Neuroblast protuberances in the subventricular zone of the regenerative MRL/MpJ mouse
2006
Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid
2010
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
2009 Standout
Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease
2005
Context-dependent neuronal differentiation and germ layer induction of Smad4−/− and Cripto−/− embryonic stem cells
2005
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
2010