Citation Impact
Citing Papers
MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4-and PAR-1-dependent phosphorylation
2008
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
2009 StandoutScience
Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS -Mutant Lung Adenocarcinoma
2015
The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
2012 Science
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
2006
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
2007
TOR Signaling in Growth and Metabolism
2006 Standout
Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491
2005
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3
2012
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases
2014
AMP-activated protein kinase: also regulated by ADP?
2011
Ceramides in insulin resistance and lipotoxicity
2005
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome
2004
AMPK signalling in health and disease
2017
KIN‐29 SIK regulates chemoreceptor gene expression via an MEF2 transcription factor and a class II HDAC
2006
mTOR Signaling in Growth Control and Disease
2012 Standout
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
2005 Nature
The LKB1/AMPK polarity pathway
2010
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
2005 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
New roles for the LKB1→AMPK pathway
2005
Mammalian TAK1 Activates Snf1 Protein Kinase in Yeast and Phosphorylates AMP-activated Protein Kinase in Vitro
2006
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
2005
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
2009
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
2014 StandoutNature
Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient mice
2005
Non-CDK-bound p27 (p27NCDK) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways
2009
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
2009
LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism
2009
Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function
2010
Sustained AMPK activation improves muscle function in a mitochondrial myopathy mouse model by promoting muscle fiber regeneration
2016
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Modulation of transcription factor function by O-GlcNAc modification
2010
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
AMPK at the Nexus of Energetics and Aging
2014
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
Dynein Modifiers in C. elegans: Light Chains Suppress Conditional Heavy Chain Mutants
2007
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Activating AMP-Activated Protein Kinase without AMP
2005
Tumor suppressors and cell metabolism: a recipe for cancer growth
2009
Autophagy in the Pathogenesis of Disease
2008 Standout
AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs
2015
The LKB1–AMPK pathway: metabolism and growth control in tumour suppression
2009
Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration
2015
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
AMPK activation: a therapeutic target for type 2 diabetes?
2014
Structural basis of AMPK regulation by small molecule activators
2013
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Cellular Fatty Acid Metabolism and Cancer
2013 Standout
Establishing Neuronal Polarity with Environmental and Intrinsic Mechanisms
2017
LKB1; linking cell structure and tumor suppression
2008
Resolution of inflammation: a new therapeutic frontier
2016
AMP-activated protein kinase and its downstream transcriptional pathways
2010
Regulation of LKB1/STRAD Localization and Function by E-Cadherin
2008
Mitochondria in the Regulation of Innate and Adaptive Immunity
2015
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
2010
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
2005
AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells
2004
Expanding roles for AMPK in skeletal muscle plasticity
2015
TAK1 activates AMPK‐dependent cytoprotective autophagy in TRAIL‐treated epithelial cells
2009
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
2007 Standout
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation
2014
Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype
2011
Neuronal polarity in C. elegans
2010
The LKB1 tumor suppressor negatively regulates mTOR signaling
2004
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Cardiac-specific Deletion of LKB1 Leads to Hypertrophy and Dysfunction
2009
The Ca 2+ /Calmodulin/CaMKK2 Axis: Nature's Metabolic CaMshaft
2016
Wnt signalling in stem cells and cancer
2005 StandoutNature
Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate
2015
Fuel feeds function: energy metabolism and the T-cell response
2005
The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor
2007
Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors
2015
Angiogenesis as a therapeutic target
2005 StandoutNature
Genetics and biology of pancreatic ductal adenocarcinoma
2006
The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence Detector
2004
Regulation of the MEX-5 Gradient by a Spatially Segregated Kinase/Phosphatase Cycle
2011
Metformin and reduced risk of cancer in diabetic patients
2005 Standout
Adenosine Monophosphate-Activated Protein Kinase: A Central Regulator of Metabolism with Roles in Diabetes, Cancer, and Viral Infection
2011
Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes
2004 StandoutNobel
Function of Mammalian LKB1 and Ca2+/Calmodulin-dependent Protein Kinase Kinase α as Snf1-activating Kinases in Yeast
2005
Predominant α2/β2/γ3 AMPK activation during exercise in human skeletal muscle
2006
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
2008
AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets
2011
Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation
2005
Identification of a Nuclear Export Signal in the Catalytic Subunit of AMP-activated Protein Kinase
2010
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
Tissue Tregs
2016
AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival
2015
Macrophage Polarization
2016 Standout
ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions
2004 Standout
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
2007
Mechanisms of Organ Injury and Repair by Macrophages
2016
Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes
2004
T reg cells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration
2018
AMP-Activated Protein Kinase as a Drug Target
2006
A MOLECULAR PERSPECTIVE OF CTLA-4 FUNCTION
2005
The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation
2006
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism
2010
Novel Fat Depot–Specific Mechanisms Underlie Resistance to Visceral Obesity and Inflammation in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice
2011
STRADα Regulates LKB1 Localization by Blocking Access to Importin-α, and by Association with Crm1 and Exportin-7
2008
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure
2011
Lkb1 Deletion Promotes Ectopic Lipid Accumulation in Muscle Progenitor Cells and Mature Muscles
2014
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain
2015
LKB1-Dependent Signaling Pathways
2006
Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
2007
AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress
2011
Current understanding of metformin effect on the control of hyperglycemia in diabetes
2016
Metabolic reprogramming and cancer progression
2020 StandoutScience
Establishment of Axon-Dendrite Polarity in Developing Neurons
2009
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
2006
Autophagy and Metabolism
2010 StandoutScience
Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms
2015
Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators
2015
Mitochondrial and performance adaptations to exercise training in mice lacking skeletal muscle LKB1
2013
AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase
2012
AMPK: A Key Sensor of Fuel and Energy Status in Skeletal Muscle
2006
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
2009
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Calmodulin-dependent protein kinase kinase-β activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP
2009
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
2007
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
2009
New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion
2010
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity
2014
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Hepatic Glucose Sensing via the CREB Coactivator CRTC2
2008 Science
SIGNALING PATHWAYS IN INTESTINAL DEVELOPMENT AND CANCER
2004
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
LKB1 Regulates Lipid Oxidation During Exercise Independently of AMPK
2013
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Works of Olga Göransson being referenced
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis
2016
Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake
2008
Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR
2004
Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase
2007
Regulation of AMP‐activated protein kinase by LKB1 and CaMKK in adipocytes
2011
Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes
2009
AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration
2013
Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes
2002
Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis
2009
Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway
2011
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
2014
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
2004
14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK
2005
The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser358 in adipocytes
2012
Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation
2006