Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Directed evolution of a genetic circuit
2002 StandoutNobel
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation
2008
The DNA-damage response in human biology and disease
2009 StandoutNature
twist is a potential oncogene that inhibits apoptosis
1999
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Leukaemia disease genes: large-scale cloning and pathway predictions
1999
Computational studies of gene regulatory networks: in numero molecular biology
2001
Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping
2000
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
p53-dependent Down-regulation of Telomerase Is Mediated by p21
2004
Analysis of loss of heterozygosity for chromosome 10 in patients with malignant astrocytic tumors: correlation with patient age and survival
2001
Chromatin Modifications and Their Function
2007 Standout
p53-Mdm2--the affair that never ends
2002
Bone marrow cells regenerate infarcted myocardium
2001 StandoutNature
Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium
2000
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
2006 Standout
Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell.
1998
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
p38MAPK is a novel DNA damage response‐independent regulator of the senescence‐associated secretory phenotype
2011
Genetic instabilities in human cancers
1998 StandoutNature
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Senescent cells: an emerging target for diseases of ageing
2017
ATM associates with and phosphorylates p53: mapping the region of interaction
1998
The p53 pathway
1999
Analysis of the Binding of p53 to DNAs Containing Mismatched and Bulged Bases
2001
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Blinded by the Light: The Growing Complexity of p53
2009 Standout
The antioxidant function of the p53 tumor suppressor
2005
Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines
2002
Immunity, Inflammation, and Cancer
2010 Standout
Regulation of the p53 Tumor Suppressor Protein
1999
Activated p53 suppresses the histone methyltransferase EZH2 gene
2004
p53 in health and disease
2007 Standout
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
2020
Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation
2000
ING Tumor Suppressor Proteins Are Critical Regulators of Chromatin Acetylation Required for Genome Expression and Perpetuation
2006
Mammalian MAP kinase signalling cascades
2001 StandoutNature
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Activation of the Cell Death Program by Nitric Oxide Involves Inhibition of the Proteasome
1999
DNA damage induces transcriptional activation of p73 by removing C-EBP repression on E2F1
2003
Correlation of molecular genetic analysis of P53 MDM2 P16 PTEN and EGFR and survival of patients with anaplastic astrocytoma and glioblastoma
2003
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Mechanisms of switching on p53: a role for covalent modification?
1999
The Ki-67 protein: From the known and the unknown
2000 Standout
The Gut-enriched Krüppel-like Factor (Krüppel-like Factor 4) Mediates the Transactivating Effect of p53 on the p21 Promoter
2000
Common 4q24 deletion in four cases of hematopoietic malignancy: early stem cell involvement?
2005
Regulation of carbamoyl phosphate synthetase by MAP kinase
2000 Nature
Identification of human brain tumour initiating cells
2004 StandoutNature
Reversible Tumorigenesis by MYC in Hematopoietic Lineages
1999
Cancer-related inflammation
2008 StandoutNature
Human T Cell Leukemia Virus Type 1 Oncoprotein Tax Targets the Human Mitotic Checkpoint Protein MAD1
1998
Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas
1999
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Identification of a Functional Link for the p53 Tumor Suppressor Protein in Dexamethasone-induced Growth Suppression
2003
Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family
2008
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
2013
Hypoxia suppresses conversion from proliferative arrest to cellular senescence
2012
Pacing-Induced Heart Failure in Dogs Enhances the Expression of p53 and p53-Dependent Genes in Ventricular Myocytes
1998
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
The curcumin analog EF24 is a novel senolytic agent
2019
Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence
2019
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
Strategies targeting cellular senescence
2018
Chk2/hCds1 functions as a DNA damage checkpoint in G1by stabilizing p53
2000
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
A versatile drug delivery system targeting senescent cells
2018
Cancer Cell Cycles
1996 StandoutScience
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study
2000
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Evidence for Replicative Repair of DNA Double-Strand Breaks Leading to Oncogenic Translocation and Gene Amplification
2002
Discovery of piperlongumine as a potential novel lead for the development of senolytic agents
2016
Surfing the p53 network
2000 StandoutNature
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
The Developmental Biology of Brain Tumors
2001
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
1999
A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy
1999 Science
Targeting senescent cells in translational medicine
2019
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
2000
The chemistry of senescence
2019
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
2008 Standout
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF)
2005
Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts
2018
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
2000 Standout
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
2006 StandoutNobel
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
Works of Olga Chernova being referenced
MYC Abrogates p53-Mediated Cell Cycle Arrest in N -(Phosphonacetyl)- l -Aspartate-Treated Cells, Permitting CAD Gene Amplification
1998
Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells
2002
Regulation and mechanisms of gene amplification
1995
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
2004 Nature
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
2006
The role of p53 in regulating genomic stability when DNA and RNA synthesis are inhibited
1995
A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors
1998
Molecular characterization of the breakpoint region associated with a constitutional t(2;15)(q34;q26) in a patient with multiple myeloma
2001
NB4S, a Member of the TBC1 Domain Family of Genes, is Truncated as a Result of a Constitutional t(1;10)(p22;q21) Chromosome Translocation in a Patient with Stage 4S Neuroblastoma
1998
Two extended arrays of a satellite DNA sequence at the centromere and at the short-arm telomere of Chinese hamster chromosome 5
1998
Molecular Definition of Chromosome Translocations Involving 10q24 and 19q13 in Human Malignant Glioma Cells
1998
The p53 Network
1998
Murine mesenchymal cells that express elevated levels of the CDK inhibitor p16(Ink4a)in vivoare not necessarily senescent
2017
A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides
1998
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
2016
Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains.
1996
Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody
2017
Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice
2012
p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli
2017
Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles.
1996
Multiple mechanisms of N -phosphonacetyl- l -aspartate resistance in human cell lines: Carbamyl- P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged
1997