Standout Papers
Citation Impact
Citing Papers
NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
2010 StandoutNobel
Tumor Repressive Functions of Estrogen Receptor β in SW480 Colon Cancer Cells
2009
Morphoproteomic Characterization of Lung Squamous Cell Carcinoma Fragmentation, a Histological Marker of Increased Tumor Invasiveness
2017
Colorectal cancer statistics, 2020
2020 Standout
The gut microbiota and host health: a new clinical frontier
2015 Standout
Regulation of the cell cycle by SCF-type ubiquitin ligases
2005
The heparanase/syndecan‐1 axis in cancer: mechanisms and therapies
2013
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
2013 Standout
Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model
2015
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
Microsatellite instability in colorectal cancer: clinicopathological significance
2015
Angiosarcoma
2010
Microsatellite Instability in Colorectal Cancer
2010 Standout
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
2012 StandoutNobel
Ovarian cancer
2014 Standout
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit
2006 StandoutNobel
Glycosaminoglycans: key players in cancer cell biology and treatment
2012
Deregulated degradation of the cdk inhibitor p27 and malignant transformation
2002
Expression and functional role of negative signalling regulators in tumour development and progression
2010
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy
2008
Function and regulation of cullin–RING ubiquitin ligases
2005 Standout
Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression
2008 Standout
The abundance and variety of carbohydrate-active enzymes in the human gut microbiota
2013 Standout
Significance of Heparanase in Cancer and Inflammation
2011
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Nasopharyngeal carcinoma
2019 Standout
Three Different Binding Sites of Cks1 Are Required for p27-Ubiquitin Ligation
2002 StandoutNobel
Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: a randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation
2011
Ubiquitin ligases: cell-cycle control and cancer
2006
Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type
1999
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
2013 Standout
Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
2010 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Is right-sided colon cancer different to left-sided colorectal cancer? – A systematic review
2014
Extracellular matrix structure
2015 Standout
p21 in cancer: intricate networks and multiple activities
2009 Standout
Identification and validation of genes involved in cervical tumourigenesis
2011
Nasopharyngeal carcinoma
2015 Standout
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Remodelling the extracellular matrix in development and disease
2014 Standout
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Diet rapidly and reproducibly alters the human gut microbiome
2013 StandoutNature
Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis
2006
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice
2011
On the statistical assessment of classifiers using DNA microarray data
2006
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
The ubiquitin system: pathogenesis of human diseases and drug targeting
2004 StandoutNobel
Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis
2004 Standout
Oncogenic aberrations of cullin-dependent ubiquitin ligases
2004
Keratin expression in human tissues and neoplasms
2002
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Applications of machine learning in drug discovery and development
2019 Standout
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Era of universal testing of microsatellite instability in colorectal cancer
2013
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
2013 Standout
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
2013 Standout
Cdc20 and Cks Direct the Spindle Checkpoint-Independent Destruction of Cyclin A
2008
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer
2008
Preclinical evaluation of sunitinib as single agent or in combination with chemotherapy in nasopharyngeal carcinoma
2010
The history and future of targeting cyclin-dependent kinases in cancer therapy
2015 Standout
Fusobacterium nucleatum — symbiont, opportunist and oncobacterium
2018 Standout
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
2010
Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein.
2003
Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer
2006 Standout
The MAPK pathway across different malignancies: A new perspective
2014 Standout
Differential strand separation at critical temperature: A minimally disruptive enrichment method for low-abundance unknown DNA mutations
2012
Hereditary gynaecological malignancies: advances in screening and treatment
2012
Expression of calreticulin is associated with infiltration of T-cells in stage IIIB colon cancer
2010
Repeated observation of breast tumor subtypes in independent gene expression data sets
2003 Standout
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome
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2012
Colorectal cancer statistics, 2017
2017 Standout
Heparanase, Hyaluronan, and CD44 in Cancers: A Breast Carcinoma Perspective
2006
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis
2007
CD8+tumor-infiltrating lymphocytes at primary sites as a possible prognostic factor of cutaneous angiosarcoma
2013 StandoutNobel
Early Events in the Pathogenesis of Epithelial Ovarian Cancer
2008
Role of the F-Box Protein Skp2 in Adhesion-Dependent Cell Cycle Progression
2001
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
2011 Standout
Annexins: From Structure to Function
2002 Standout
The Ubiquitin-Proteasome Pathway and Its Role in Cancer
2005
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
2007 Standout
Cyclin-Dependent Kinase Inhibitor p27 As a Prognostic Biomarker and Potential Cancer Therapeutic Target
2010
Long‐term Treatment of Primary Sclerosing Cholangitis in Children With Oral Vancomycin: An Immunomodulating Antibiotic
2008
Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.
2002
Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
2002
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Immunogenic Cell Death in Cancer Therapy
2012 Standout
Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
2002
Works of Ofer Ben‐Izhak being referenced
Heparanase Expression in Malignant Salivary Gl, Tumors Inversely Correlates with Long-Term Survival
2006
The expression of the ubiquitin ligase subunit Cks1 in human breast cancer
2005
Expression of HER2 and C-KIT in Nasopharyngeal Carcinoma: Implications for a New Therapeutic Approach
2003
Heparanase upregulation by colonic epithelium in inflammatory bowel disease
2006
Over-expression of Skp2 is associated with resistance to preoperative doxorubicin-based chemotherapy in primary breast cancer
2008
Pathologic Predictors of Microsatellite Instability in Colorectal Cancer
2008
Heparanase expression by Barrett's epithelium and during esophageal carcinoma progression
2009
Development of a Computerized Morphometry Application for Assessment of the Tumor Fraction in Colon Carcinoma Tissue Samples
2012
Downregulation of Sef, an inhibitor of receptor tyrosine kinase signaling, is common to a variety of human carcinomas
2007
Heparanase is overexpressed in lung cancer and correlates inversely with patient survival
2008
Prevalence and relevance of EBV latency in nasopharyngeal carcinoma in Israel
2004
Epithelial Markers in Malignant Melanoma
1994
Heparanase up‐regulation in tongue cancer
2007
Prognostic value of heparanase expression and cellular localization in oral cancer
2010
Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma
2004
Expression of cell cycle regulatory proteins in ovaries prophylactically removed from Jewish Ashkenazi BRCA1 and BRCA2 mutation carriers: Correlation with histopathology
2005
Severe pulmonary disease in association with Crohn's disease in a 13-year-old girl
2000
Heparanase Induces Signal Transducer and Activator of Transcription (STAT) Protein Phosphorylation
2011
Inverse relation between levels of p27Kip1 and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas
2001 StandoutNobel
Human heparanase nuclear localization and enzymatic activity
2004
Oropharyngeal cancer pathogenesis: Ubiquitin proteolytic, apoptotic and epidermal growth factor related pathways act in concert—first report
2005
The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma
2005
Heparanase expression in nasopharyngeal carcinoma inversely correlates with patient survival
2006
Regulation of the cell cycle inhibitor p27 and its ubiquitin ligase Skp2 in differentiation of human embryonic stem cells
2007
LNA-based PCR clamping enrichment assay for the identification of KRAS mutations
2011
Angiosarcoma of the Colon Developing in a Capsule of a Foreign Body: Report of a Case with Associated Hemorrhagic Diathesis
1992
Inverse Relationship Between Skp2 Ubiquitin Ligase and the Cyclin Dependent Kinase Inhibitor p27 Kip1 in Prostate Cancer
2003 StandoutNobel