Citation Impact
Citing Papers
A Novel Orally Active Small Molecule Potently Induces G1 Arrest in Primary Myeloma Cells and Prevents Tumor Growth by Specific Inhibition of Cyclin-Dependent Kinase 4/6
2006
Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines
2009
The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.
1990 StandoutNobel
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease
2001
Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes
1988 StandoutNature
Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle
1989 StandoutNatureNobel
Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25
2000
Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import
1999
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
2011 StandoutNobel
Cell-cycle checkpoints and cancer
2004 StandoutNature
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
2001 StandoutNature
The GTPase superfamily: a conserved switch for diverse cell functions
1990 StandoutNature
ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
1991 Standout
Cyclin‐dependent kinase inhibitors for treating cancer
2001
The Use ofXenopusOocytes for the Study of Ion Channel
1987
Mammalian Ras interacts directly with the serine/threonine kinase raf
1993 Standout
Chemical inhibitors of cyclin-dependent kinases
1997
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
The generation of diversity and pattern in animal development
1992 StandoutNobel
Modulation of the substrate specificity of the polycation‐stimulated protein phosphatase from Xenopus laevis oocytes
1988
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
1990 StandoutNobel
Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid
1993 StandoutNature
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Oocyte Maturation in Amphibians
1985
Differential regulation of histone H1 and ribosomal S6 kinases during sea star oocyte maturation
1987 StandoutNobel
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase
1990 StandoutNatureNobel
Initiation of Human DNA Replication in Vitro Using Nuclei from Cells Arrested at an Initiation-competent State
2000
Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis
1989 StandoutNobel
Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+
1988 StandoutNobel
Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition
2010
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
1999 Standout
Inhibition of Cyclin‐Dependent Kinases by Purine Analogues
1997
High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications
1999
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol
2002
Activation of p34cdc2 kinase by cyclin is negatively regulated by cyclic Amp-dependent protein kinase in Xenopus oocytes
1992
Regulation of Peroxiredoxin I Activity by Cdc2-mediated Phosphorylation
2002
Cyclin-dependent kinases as new targets for the prevention and treatment of cancer
2002
Synapsins as mediators of BDNF-enhanced neurotransmitter release
2000 StandoutNobel
Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis
2006
Sequential and Synergistic Modification of Human RPA Stimulates Chromosomal DNA Repair
2007
Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors
1999
Regulation of G2/M events by Cdc25A through phosphorylation-dependent modulation of its stability
2002
Patch Clamp Studies on V-type ATPase of Vacuolar Membrane of Haploid Saccharomyces cerevisiae
1999 StandoutNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Proteolytic degradation of the nuclear isoform of uracil-DNA glycosylase occurs during the S phase of the cell cycle
2004
Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors
2000
c-Myc or Cyclin D1 Mimics Estrogen Effects on Cyclin E-Cdk2 Activation and Cell Cycle Reentry
1998
Phosphorylation changes associated with the early cell cycle in Xenopus eggs
1987
The pure inhibitor of cAMP-dependent protein kinase initiates Xenopus laevis meiotic maturation
1981 StandoutNobel
Preliminary characterization of maturation-promoting factor from yeast Saccharomyces cerevisiae *
1987
Reconstitution of I KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor
1995 StandoutScience
H 2 O 2 , a Necessary Evil for Cell Signaling
2006 StandoutScience
Regulation of amphibian oocyte maturation
1985
Cdk2 is Required for Breast Cancer Mediated by the Low-Molecular-Weight Isoform of Cyclin E
2011
Opening of glibenclamide-sensitive K+ channels in follicular cells promotes Xenopus oocyte maturation.
1992
Targeted mutations in the Caenorhabditis elegans POU homeo box gene ceh-18 cause defects in oocyte cell cycle arrest, gonad migration, and epidermal differentiation.
1994 StandoutNobel
Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs.
1987 StandoutNobel
Purification and characterization of a maturation-activated myelin basic protein kinase from sea star oocytes.
1990
Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase.
1989 StandoutNobel
Calcium-mediated transduction of the hormonal message in meiosis reinitiation of starfish oocytes
1981
The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs.
1993 StandoutNobel
Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes.
1995 StandoutNobel
p34cdc2 acts as a lamin kinase in fission yeast.
1991 StandoutNobel
The timing of early developmental events in Xenopus
1985
Maturation promoting factor and cell cycle regulation
1985
The specificities of protein kinase inhibitors: an update
2003 Standout
Paullones, a Series of Cyclin-Dependent Kinase Inhibitors: Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity
1999 Standout
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
Oocyte Maturation
1979
The induction of oocyte maturation: transmembrane signaling events and regulation of the cell cycle
1989
Xenopus laevis oocyte calmodulin in the process of meiotic maturation.
1980
Adenylate cyclase in Xenopus laevis oocytes: Characterization of the progesterone-sensitive, membrane-bound form
1982
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
The Structure of Sister Minichromosome DNA Before Anaphase in Saccharomyces Cerevisiae
1987 StandoutScienceNobel
Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis
2009
Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.
1990 StandoutNobel
The selectivity of protein kinase inhibitors: a further update
2007 Standout
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
1999 Standout
Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library
2000 StandoutNobel
p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.
1989 StandoutNobel
Purification of MPF from starfish: Identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation
1989 StandoutNobel
Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes
1986 StandoutNatureNobel
RAS proteins can induce meiosis in xenopus oocytes
1985
In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R‐roscovitine)
2002
Dynamic and quantitative Ca 2+ measurements using improved cameleons
1999 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
c-AMP-dependent protein kinases and the control of progesterone-induced maturation in amphibian oocytes
1978
Works of Odile Mulner being referenced
Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5
1997
Calmodulin modulates the cyclic AMP level in Xenopus oocyte
1983
Progesterone Biosynthesis and Metabolism by Ovarian Follicles and Isolated Oocytes of Xenopus laevis
1976
Cyclic AMP synthesis in Xenopus laevis oocytes inhibition by progesterone
1979
Pertussis toxin facilitates the progesterone‐induced maturation of Xenopus oocyte
1985
Roles of cyclic amp and calcium in maturation of Xenopus laevis oocytes
1979
Cyclic AMP Phosphodiesterase Activities in Xenopus laevis Oocytes
1980
The roles of follicular envelopes in the initiation of Xenopus oocyte maturation
1981
In vivo effects of microinjected alkaline phosphatase and its low molecular weight substrates on the first meiotic cell division in Xenopus laevis oocytes.
1984
cAMP-dependent protein kinase regulates in ovo camp level of the Xenopus oocyte: Evidence for an intracellular feedback mechanism
1983