Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine
2001 StandoutScience
HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol
2005 Standout
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
The HIV-1 Nef Protein and Phagocyte NADPH Oxidase Activation
2002
Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome
2007
Pathophysiology of uric acid nephrolithiasis
2002
Gout and hyperuricemia
2002
Kidney stones: pathophysiology and medical management
2006 Standout
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
2002 StandoutNature
Novel insights into the pathogenesis of uric acid nephrolithiasis
2004
Thyroid hormones and the creatine kinase system in cardiac cells
1994
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
Serum Uric Acid and Cardiovascular Mortality
2000 Standout
Lung Cancer
2008 Standout
Expression of purine metabolism-related enzymes by microglial cells in the developing rat brain
1998
Disorders of purine and pyrimidine metabolism
2005
Adenosine receptors as therapeutic targets
2006 Standout
Cloning and Characterization of Human Guanine Deaminase
1999
The biology and function of fibroblasts in cancer
2016 Standout
Gout epidemiology: results from the UK General Practice Research Database, 1990–1999
2005
Uric Acid and Cardiovascular Risk
2008 Standout
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Developmental expression of adenosine deaminase in the upper alimentary tract of mice
1990
Purines, the carotid body and respiration
2007
ATP mediates rapid microglial response to local brain injury in vivo
2005 Standout
Structure and function of xanthine oxidoreductase: where are we now?
2002
Gout
2009 Standout
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
The Pathogenesis and Treatment of Kidney Stones
1992
Obesity, Weight Gain, and the Risk of Kidney Stones
2005 Standout
Role of interleukin-6 in cancer progression and therapeutic resistance
2016
Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans
2008
Xanthine Oxidoreductase Is a Regulator of Adipogenesis and PPARγ Activity
2007
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
2011 StandoutNature
Dual Role of Rac in the Assembly of NADPH Oxidase, Tethering to the Membrane and Activation of p67
2004
Identification and characterization of the first mutation (Arg776Cys) in the C-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS) associated with type II classical xanthinuria
2007
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
2008
Binding of Xanthine Oxidase to Vascular Endothelium
1999
Gout
2016 Standout
Xanthine oxidase activity in the circulation of rats following hemorrhagic shock
1993
Erythrocyte‐Inspired Delivery Systems
2012
Frequency of specific cancer types in dermatomyositis and polymyositis: a population-based study
2001 Standout
Cardiotoxicity of Chemotherapeutic Agents
2000
Identification of a New Candidate Locus for Uric Acid Nephrolithiasis
2001
A Prospective Study of Dietary Calcium and Other Nutrients and the Risk of Symptomatic Kidney Stones
1993 Standout
Increased Monocyte Interleukin-1 Activity and Decreased Vertebral Bone Density in Patients with Fasting Idiopathic Hypercalciuria
1990
The immunology of stroke: from mechanisms to translation
2011 Standout
Gout in Solid Organ Transplantation
2005
Sickle-cell disease
2010 Standout
URIC ACID–RELATED NEPHROLITHIASIS
1997
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease
2005
Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol
2006 Standout
British Society for Rheumatology and British Health Professionals in Rheumatology Guideline for the Management of Gout
2007
Comparison of Two Diets for the Prevention of Recurrent Stones in Idiopathic Hypercalciuria
2002 Standout
Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout
2005 Standout
Gene-expression profiles predict survival of patients with lung adenocarcinoma
2002 Standout
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Inherited Hyperuricemic Disorders
2004
Colloidal gold nanoparticle modified carbon paste interface for studies of tumor cell adhesion and viability
2005
Suspected Allopurinol‐Induced Aseptic Meningitis
2001
Biomimetic Engineering of Carbon Nanotubes by Using Cell Surface Mucin Mimics
2004 StandoutNobel
Hierarchical Assembly of Model Cell Surfaces: Synthesis of Mucin Mimetic Polymers and Their Display on Supported Bilayers
2007 StandoutNobel
Testing an “In-Out” Targeting Procedure for Making Subtle Genomic Modifications in Mouse Embryonic Stem Cells
1991 StandoutNobel
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility
2008
Pathophysiologic basis for normouricosuric uric acid nephrolithiasis
2002
Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease
2001
Familial Idiopathic Hypercalciuria
1979
Hypercalciuria and Hyperuricosuria in Patients with Calcium Nephrolithiasis
1974
Repeated observation of breast tumor subtypes in independent gene expression data sets
2003 Standout
A comparative study of purine metabolism by human and pig erythrocytes in vitro
1973
Metabolic Cooperation between Cells
1981
Lectins: Carbohydrate-Specific Proteins That Mediate Cellular Recognition
1998 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Pivotal role of NOX‐2‐containing NADPH oxidase in early ischemic preconditioning
2005
The Purine Path to Chemotherapy (Nobel Lecture)
1989 Nobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.
1991 StandoutNobel
The Purine Path to Chemotherapy
1989 ScienceNobel
Activation of the Nuclear Factor-κB Is a Key Event in Brain Tolerance
2001
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Effects of low-calcium diet on urine calcium excretion, parathyroid function and serum 1,25(OH)2D3 levels in patients with idiopathic hypercalciuria and in normal subjects
1982
P2Y1 and Cysteinyl Leukotriene Receptors Mediate Purine and Cysteinyl Leukotriene Co-Release in Primary Cultures of Rat Microglia
2005
Current molecular models for NADPH oxidase regulation by Rac GTPase
2002
Lectin Receptors as Lymphocyte Surface Markers
1983
Gout
2021 Standout
Specificity of adenylosuccinate synthetase and adenylosuccinate lyase from Leishmania donovani. Selective amination of an antiprotozoal agent.
1979 StandoutNobel
Chemical Modification of the Multitarget Neuroprotective Compound Fisetin
2011
Interaction of Rac with p67 phox and Regulation pf Phagocytic NADPH Oxidase Activity
1994 Science
The Mononuclear Molybdenum Enzymes
2014 Standout
Involvement of astrocytes in purine‐mediated reparative processes in the brain
2001
Early Detection of Anthracycline Cardiotoxicity and Improvement With Heart Failure Therapy
2015 Standout
Degradation and resynthesis of adenine nucleotides in adult rat heart myocytes.
1987
Electrochemical Antitumor Drug Sensitivity Test for Leukemia K562 Cells at a Carbon‐Nanotube‐Modified Electrode
2005
Dermatomyositis without creatine kinase elevation. A poor prognostic sign
1986
Familial Absorptive Hypercalciuria in a Large Kindred
1981
Azido Push−Pull Fluorogens Photoactivate to Produce Bright Fluorescent Labels
2009 StandoutNobel
Chemistry of Carbon Nanotubes
2006 Standout
Synthesis of Photoactive α‐Mannosides and Mannosyl Peptides and Their Evaluation for Lectin Labeling
2006
Circulating xanthine oxidase: potential mediator of ischemic injury
1990
Creatine and Creatinine Metabolism
2000 Standout
Physiology of Microglia
2011 Standout
Works of Oded Sperling being referenced
Oxidative Stress Activates Transcription Factor NF-kB-Mediated Protective Signaling in Primary Rat Neuronal Cultures
2005
Activation and inhibition of protein kinase C protect rat neuronal cultures against ischemia-reperfusion insult
1997
Molecular, biochemical, and genetic characterization of a female patient with Lesch–Nyhan disease
2005
Metabolism of Guanine and Guanine Nucleotides in Primary Rat Cardiomyocyte Cultures
1995
Adenosine-Induced Preconditioning of Rat Neuronal Cultures Against Ischemia-Reperfusion Injury
1998
Developmental Changes in the Activity of Enzymes of Purine Metabolism in Rat Neuronal Cells in Culture and in Whole Brain
1990
Protein kinase C‐ε is involved in the adenosine‐activated signal transduction pathway conferring protection against ischemia‐reperfusion injury in primary rat neuronal cultures
2003
Polymorphic Markers in the XDH Gene as Diagnostic Tools for Typing Classical Xanthinuria
2006
Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures
2004
Opening of ATP-sensitive potassium channels by cromakalim confers tolerance against chemical ischemia in rat neuronal cultures
1998
Pathways of adenine nucleotide catabolism in primary rat muscle cultures
1987
Metabolic and calcium kinetic studies in idiopathic hypercalciuria
1968
Abnormal Purine and Pyrimidine Nucleotide Content in Primary Astroglia Cultures from Hypoxanthine—Guanine Phosphoribosyltransferase‐Deficient Transgenic Mice
1999
Reactive oxygen species play an important role in iodoacetate-induced neurotoxicity in primary rat neuronal cultures and in differentiated PC12 cells
2003
Hereditary renal hypouricemia
2006
XDH gene mutation is the underlying cause of classical xanthinuria: A second report
2000
Elevation of serum xanthine oxidase following halothane anesthesia in the rat
1976
Total lactate dehydrogenase and its isoenzymes in serum of patients with non-small-cell lung cancer.
1988
Familial Hypouricemia Due to Isolated Renal Tubular Defect
1977
Hypouricemia, Hypercalciuria, and Decreased Bone Density: A Hereditary Syndrome
1974
Metabolic cooperation between human fibroblasts with normal and with mutant superactive phosphoribosylpyrophosphate synthetase
1976 Nature
Trivalent Cluster Mannosides with Aromatic Partial Structure as Ligands for the Type 1 Fimbrial Lectin of Escherichia coli
2002
Uric acid nephrolithiasis.
1994
Developmental changes in purine nucleotide metabolism in cultured rat astroglia
1995
Proceedings: Serum xanthine oxidase in hepatocellular damage.
1975
Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor‐mediated mechanisms
2001
Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in red blood cells.
1972
Accelerated erythrocyte 5-phosphoribosyl-1-pyrophosphate synthesis. A familial abnormality associated with excessive uric acid production and gout
1972
Differences in the activity of adenosine deaminase and of purine nucleoside phosphorylase and in the sensitivity to deoxypurine nucleosides between subpopulations of mouse thymocytes.
1982
Purine and Pyrimidine Metabolism in Man X
2002
Familial Renal Hypouricaemia: Two Additional Cases with Uric Acid Lithiasis
1979
Renal Ammonium Excretion and Urinary Ph in Idiopathic Uric Acid Lithiasis
1964
The mechanism of hyperuricaemia in cyclosporine-treated renal transplant recipients.
1987
Purine nucleotide metabolism in cultured neurons and astroglia from HPRT-deficient knockout mice.
2002
Serum xanthine oxidase in jaundice
1975
The GDP-bound form of the small G protein Rac1 p21 is a potent activator of the superoxide-forming NADPH oxidase of macrophages.
1994
The Kinetics of Intramolecular Distribution of 15N in Uric Acid after Administration of [15N]Glycine A REAPPRAISAL OF THE SIGNIFICANCE OF PREFERENTIAL LABELING OF N-(3 + 9) OF URIC ACID IN PRIMARY GOUT
1973
Characterization of purine nucleotide metabolism in primary rat cardiomyocyte cultures
1984
Low serum creatine phosphokinase values in patients with acute viral hepatitis.
1984
Thyroxine-induced redistribution of creatine kinase isoenzymes in rat cardiomyocyte cultures
1989
Elevation of serum xanthine oxidase activity following halothane anesthesia in man
1977
Allopurinol in the Prophylaxis of Uric Acid Stones
1966