Citation Impact
Citing Papers
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
1998 Nature
Hallmarks of Cancer: The Next Generation
2011 Standout
Drosophila Tcf and Groucho interact to repress Wingless signalling activity
1998 Nature
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Caught up in a Wnt storm: Wnt signaling in cancer
2003
Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function
2004
Gut Reaction to Wnt Signaling in Worms
1997
On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
2001 StandoutNobel
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
mTOR Signaling in Growth Control and Disease
2012 Standout
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Wnt Signaling Regulates B Lymphocyte Proliferation through a LEF-1 Dependent Mechanism
2000
β-catenin: a key mediator of Wnt signaling
1998
TCF transcription factors: molecular switches in carcinogenesis
1999
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Wnt signalling: a theme with nuclear variations
2001
Transcription factors as targets for cancer therapy
2002
The Crystal Structure of the β-Catenin/ICAT Complex Reveals the Inhibitory Mechanism of ICAT
2002
Covalent histone modifications — miswritten, misinterpreted and mis-erased in human cancers
2010
Pygopus, a nuclear PHD-finger protein required for Wingless signaling inDrosophila
2002
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 StandoutNobel
Carcinogenesis: A balance between β-catenin and APC
1997
eyelidantagonizes wingless signaling during Drosophiladevelopment and has homology to the Bright family of DNA-binding proteins
1997
Transcription under the Control of Nuclear Arm/β-Catenin
2006
A Nuclear Function for Armadillo/β-Catenin
2004 Nobel
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans
1999 Nature
Dishevelled Activates JNK and Discriminates between JNK Pathways in Planar Polarity and wingless Signaling
1998
Stem cells find their niche
2001 StandoutNature
Wnt signaling in the intestinal epithelium: from endoderm to cancer
2005
Wntless, a Conserved Membrane Protein Dedicated to the Secretion of Wnt Proteins from Signaling Cells
2006
LEF-1, a Nuclear Factor Coordinating Signaling Inputs from wingless and decapentaplegic
1997
Regulation of TCF3 by Wnt-Dependent Phosphorylation during Vertebrate Axis Specification
2010
Vertebrate Proteins Related to Drosophila Naked Cuticle Bind Dishevelled and Antagonize Wnt Signaling
2001
Three-Dimensional Structure of the Armadillo Repeat Region of β-Catenin
1997
TCF-4 binds β-catenin and is expressed in distinct regions of the embryonic brain and limbs
1998
Wnt signaling: a common theme in animal development
1997 Standout
A Versatile Transcriptional Effector of Wingless Signaling
1997
Parafibromin/Hyrax Activates Wnt/Wg Target Gene Transcription by Direct Association with β-catenin/Armadillo
2006
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
2006 StandoutNobel
Characterization of Mouse Dishevelled (Dvl) Proteins in Wnt/Wingless Signaling Pathway
1999
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling
1998 Nature
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
2009
Wnt/β-Catenin Signaling and Disease
2012 Standout
C. elegans TCF protein, POP-1, converts from repressor to activator as a result of Wnt-induced lowering of nuclear levels
2005
naked cuticle targets dishevelled to antagonize Wnt signal transduction
2001
A role for Wnt signalling in self-renewal of haematopoietic stem cells
2003 StandoutNature
Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development
2007
Secretion of Wnt Ligands Requires Evi, a Conserved Transmembrane Protein
2006
Accumulation of Armadillo Induced by Wingless, Dishevelled, and Dominant-negative Zeste-white 3 Leads to Elevated DE-cadherin inDrosophila Clone 8 Wing Disc Cells
1997
A new nuclear component of the Wnt signalling pathway
2002
Armadillo and dTCF: a marriage made in the nucleus
1997 Standout
Wnt signaling in disease and in development
2005
Linking Colorectal Cancer to Wnt Signaling
2000
Genetics of morphogen gradients
2001
Regulation of LEF-1/TCF transcription factors by Wnt and other signals
1999
The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans
2002 StandoutNobel
BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration
2009
Regulation of Armadillo by a Drosophila APC Inhibits Neuronal Apoptosis during Retinal Development
1998 Nobel
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Distinct β-catenins mediate adhesion and signalling functions in C. elegans
2000 Nature
A β-catenin/XTcf-3 complex binds to thesiamois promoter to regulate dorsal axis specification in Xenopus
1997
Pygopus and Legless Provide Essential Transcriptional Coactivator Functions to Armadillo/β-Catenin
2005
Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis
2003 StandoutNature
Wnt Signaling Polarizes an Early C. elegans Blastomere to Distinguish Endoderm from Mesoderm
1997
RNA interference
2002 StandoutNature
Wnt3a-/--like phenotype and limb deficiency in Lef1-/-Tcf1-/- mice
1999
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
The C-terminal domain of Armadillo binds to hypophosphorylated Teashirt to modulate Wingless signalling in Drosophila
1999
Revealing the world of RNA interference
2004 StandoutNatureNobel
LEF-1/TCF Proteins Mediate Wnt-Inducible Transcription from the Xenopus Nodal-Related 3 Promoter
1997
Structure of the nuclear transport complex karyopherin-β2–Ran˙GppNHp
1999 StandoutNatureNobel
Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway
2003 Nature
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
2005
ICAT Inhibits β-Catenin Binding to Tcf/Lef-Family Transcription Factors and the General Coactivator p300 Using Independent Structural Modules
2002
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
Wnt signalling in stem cells and cancer
2005 StandoutNature
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
Wingless secretion promotes and requires retromer-dependent cycling of Wntless
2008
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
2010
Use of dsRNA-Mediated Genetic Interference to Demonstrate that frizzled and frizzled 2 Act in the Wingless Pathway
1998
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
1998 StandoutNature
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Boca, an Endoplasmic Reticulum Protein Required for Wingless Signaling and Trafficking of LDL Receptor Family Members in Drosophila
2003
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
1998
The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
1999 Nature
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Regulation of Neurotrophin-3 Expression by Epithelial-Mesenchymal Interactions: The Role of Wnt Factors
1999 StandoutScienceNobel
Interaction of chlamydiae and host cells in vitro
1991
Wnt-1 Induces Growth, Cytosolic β-Catenin, and Tcf/Lef Transcriptional Activation in Rat-1 Fibroblasts
1998
Analysis of the Signaling Activities of Localization Mutants of β-Catenin during Axis Specification in Xenopus
1997
Modulation of Transcriptional Regulation by LEF-1 in Response to Wnt-1 Signaling and Association with β-Catenin
1998
Quiescent gastric stem cells maintain the adult Drosophila stomach
2011
Pathway Specificity by the Bifunctional Receptor Frizzled Is Determined by Affinity for Wingless
2000
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Wnt signaling and cancer
2000 Standout
Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
1998
Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of β-catenin/Arm and stimulation of target gene expression
2008
Inhibition of Adipogenesis by Wnt Signaling
2000 StandoutScience
Inhibition of Wnt signaling by ICAT, a novel β-catenin-interacting protein
2000
Regulation of Lymphoid Enhancer Factor 1/T-Cell Factor by Mitogen-Activated Protein Kinase-Related Nemo-Like Kinase-Dependent Phosphorylation in Wnt/β-Catenin Signaling
2003
Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis
2007 StandoutScience
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:Arrows point the way
2004
Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development
2003
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Emerging Infectious Diseases of Wildlife-- Threats to Biodiversity and Human Health
2000 StandoutScience
MECHANISMS OF WNT SIGNALING IN DEVELOPMENT
1998 Standout
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE
2004 Standout
Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1
1999
Negative regulation of Armadillo, a Wingless effector in Drosophila
1997
The Biological and Social Phenomenon of Lyme Disease
1993 Science
Wingless signaling generates pattern through two distinct mechanisms
1997
Wingless signaling in the Drosophila embryo: zygotic requirements and the role of the frizzled genes
1999 Nobel
T cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant β-catenin
1999
Regulation of the Twist target gene tinman by modular cis-regulatory elements during early mesoderm development
1997
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
2000 StandoutNature
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
RNAi in C. elegans : Soaking in the Genome Sequence
1998 StandoutScienceNobel
A Screen for Identifying Genes Interacting With Armadillo, the Drosophila Homolog of β-Catenin
1999
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
1999
Cytoskeletal reorganization by soluble Wnt‐3a protein signalling
1998
Dfrizzled-3, a new Drosophila Wnt receptor, acting as an attenuator of Wingless signaling in wingless hypomorphic mutants
1999
Morphogen gradient interpretation
2001 StandoutNatureNobel
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
1998 StandoutScience
Interaction of Dishevelled and Xenopus Axin-Related Protein Is Required for Wnt Signal Transduction
2000
Frizzled and DFrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development
1999
Works of O Péter being referenced
Evolution of novel tricyclic CRTh2 receptor antagonists from a (E)-2-cyano-3-(1H-indol-3-yl)acrylamide scaffold
2012
pangolinencodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila
1997 Nature
Wnt/Wingless Signaling Requires BCL9/Legless-Mediated Recruitment of Pygopus to the Nuclear β-Catenin-TCF Complex
2002
Population genetic analysis of Borrelia burgdorferi isolates by multilocus enzyme electrophoresis
1992
Isolation by a sensitive centrifugation cell culture system of 52 strains of spotted fever group rickettsiae from ticks collected in France
1990
Identification of 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) Antagonist
2013