Citation Impact
Citing Papers
Cardiac Hypertrophy: The Good, the Bad, and the Ugly
2003 Standout
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
The hVps34‐ SGK 3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC 1 and tumour growth
2016
A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway
1997
Discovery of zoniporide: A potent and selective sodium–hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility
2001
HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes
2006 StandoutNobel
PI3K signaling in cancer: beyond AKT
2017
Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein
2014 Standout
QM/MM Methods for Biomolecular Systems
2009 Standout
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1
2007 StandoutNobel
The Molecular Biology of Cyclic Nucleotide Phosphodiesterases
1999
Cancer to bone: a fatal attraction
2011 Standout
A novel approach for assesing macromolecular complexes combining soft‐docking calculations with NMR data
2001
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
2005 Standout
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use
2006 Standout
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
2004 Standout
Left ventricular dysfunction and associated cellular injury in rats exposed to chronic intermittent hypoxia
2007
The nitric oxide and cGMP signal transduction system: regulation and mechanism of action
1993
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Network pharmacology: the next paradigm in drug discovery
2008 Standout
Molecular organization of bovine rod cGMP-phosphodiesterase 6
2001
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
2005 Standout
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
2013 Standout
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
2011 Standout
Ca2+-calmodulin-dependent phosphodiesterase (PDE1): Current perspectives
2005
Cannabinoids Stimulate Fibroblastic Colony Formation by Bone Marrow Cells Indirectly via CB2 Receptors
2007
Na+/h+exchange inhibitors for cardioprotective therapy: progress, problems and prospects
2002
Cyclic nucleotide phosphodiesterases: Pharmacology, biochemistry and function
1991
2007 Guidelines for the Management of Arterial Hypertension
2007 Standout
Cyclic nucleotide phosphodiesterases: Relating structure and function
2000
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
1999 Standout
Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning
2003 Standout
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Isolation and Characterization of PDE9A, a Novel Human cGMP-specific Phosphodiesterase
1998
Drug repurposing: progress, challenges and recommendations
2018 Standout
Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation
2003 Standout
Up-Regulation of Kir2.1 (KCNJ2) by the Serum & Glucocorticoid Inducible SGK3
2014
Plant Polyphenols as Dietary Antioxidants in Human Health and Disease
2009 Standout
Sgk1-Dependent Stimulation of Cardiac Na+/H+Exchanger Nhe1 by Dexamethasone
2013
The effect of SK&F 95654, a novel phosphodiesterase inhibitor, on cardiovascular, respiratory and platelet function
1992
Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs)
2005
Gene Pathways That Delay Caenorhabditis elegans Reproductive Senescence
2014 StandoutNobel
An overview of inhibitors of Na+/H+ exchanger
2003
Evaluation and ranking of enzyme designs
2010 StandoutNobel
NMR structure determination of proteins supplemented by quantum chemical calculations: Detailed structure of the Ca2+ sites in the EGF34 fragment of protein S
2005
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury
2003
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
2015 Standout
Myocardial Reperfusion Injury
2007 Standout
Modulation of mitochondrial adenosine triphosphate-sensitive potassium channels and sodium-hydrogen exchange provide additive protection from severe ischemia-reperfusion injury
2003
Effect of Carbon Monoxide Donor CORM-2 on Vitamin D<sub>3</sub> Metabolism
2013
Reperfusion injury in humans: A review of clinical trials on reperfusion injury inhibitory strategies
2007
AKT/PKB Signaling: Navigating the Network
2017 Standout
The Na+/H+exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction11This manuscript is dedicated to the memory of Karl-Ludwig Neuhaus (1944–2000).
2001
The PI3K Pathway in Human Disease
2017 Standout
Excitation-contraction coupling and mitochondrial energetics
2007
Solubilization of Membrane-bound Rod Phosphodiesterase by the Rod Phosphodiesterase Recombinant δ Subunit
1996
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
2009 StandoutNobel
Impairment of sodium pump and Na/H exchanger in erythrocytes from non-insulin dependent diabetes mellitus patients: effect of tea catechins
2004
[13] Nitric oxide-cyclic GMP signal transduction system
1996 StandoutNobel
Isolation and Characterization of PDE8A, a Novel Human cAMP-Specific Phosphodiesterase
1998
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3′,5′-cyclic nucleotide phosphodiesterase
1997
An Essential Aspartic Acid at Each of Two Allosteric cGMP-binding Sites of a cGMP-specific Phosphodiesterase
1995
Selective Optimization of Side Activities: Another Way for Drug Discovery
2004
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Inhibition of the Sodium-Hydrogen Exchanger With Cariporide to Prevent Myocardial Infarction in High-Risk Ischemic Situations
2000
Dickkopf Homolog 1 Mediates Endothelin-1-Stimulated New Bone Formation
2006
Characterization of the structure of a low Km, rolipram-sensitive cAMP phosphodiesterase. Mapping of the catalytic domain.
1992
Graphenes as Potential Material for Electronics
2007 Standout
Guanylyl Cyclases and Signaling by Cyclic GMP
2000 Standout
Recent progress in the synthesis of 1,2,3,4,-tetrahydroquinolines
1996 Standout
Diabetic Cardiomyopathy
2018 Standout
Discotic liquid crystalline hexabenzocoronenes carrying chiral and racemic branched alkyl chains: supramolecular engineering and improved synthetic methods
2001
SGK KINASES AND THEIR ROLE IN EPITHELIAL TRANSPORT
2005
Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase.
1992
Test MM-PB/SA on True Conformational Ensembles of Protein−Ligand Complexes
2010
Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack
2006 Standout
Expression of Na+-d -glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences
2012
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms
1995 Standout
Protecting the ischaemic and reperfused myocardium in acute myocardial infarction: distant dream or near reality?
2000
HADDOCK: A Protein−Protein Docking Approach Based on Biochemical or Biophysical Information
2003 Standout
Copper in cross-coupling reactions
2004 Standout
Molecular cloning of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase cDNA. Identification and distribution of isozyme variants.
1991
Na+/H+exchange inhibition attenuates hypertrophy and heart failure in 1-wk postinfarction rat myocardium
2000
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator
2001 StandoutNobel
Novel diazinone derivatives separate myofilament Ca2+ sensitization and phosphodiesterase III inhibitory effects in guinea pig myocardium.
1992
Pathophysiology of Sleep Apnea
2010 Standout
Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney
2011
The Changing Face of the Na+/H+ Exchanger, NHE1: Structure, Regulation, and Cellular Actions
2002
Catalytic amination of 5-iodouracil derivatives
2001
The structure of a bovine lung cGMP-binding, cGMP-specific phosphodiesterase deduced from a cDNA clone.
1993
Regulation of Vascular Smooth Muscle Soluble Guanylate Cyclase Activity, mRNA, and Protein Levels by cAMP-Elevating Agents
1995 StandoutNobel
N-aryl heterocycles via coupling reactions with arylboronic acids
1999
Phosphodiesterase Type 5
2007
Zinc interactions and conserved motifs of the cGMP-binding cGMP-specific phosphodiesterase suggest that it is a zinc hydrolase.
1994
Albumin-Catalyzed Proton Transfer
1996
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Inhibition of the Na+/H+Exchanger Confers Greater Cardioprotection Against 90 Minutes of Myocardial Ischemia Than Ischemic Preconditioning in Dogs
1999
Novel, Non-acylguanidine-type Na+/H+ Exchanger Inhibitors: Synthesis and Pharmacology of 5-Tetrahydroquinolinylidene Aminoguanidine Derivatives
2002
Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling
2007 Standout
Prevention Conference VI: Diabetes and Cardiovascular Disease
2002
Free Radicals in the Physiological Control of Cell Function
2002 Standout
About Supramolecular Assemblies of π-Conjugated Systems
2005 Standout
Involvement of Na+/H+ exchanger in hypoxia/re-oxygenation-induced neonatal rat cardiomyocyte apoptosis
2004
Works of Norbert Beier being referenced
Tripeptides of RS1 (RSC1A1) Inhibit a Monosaccharide-dependent Exocytotic Pathway of Na+-d-Glucose Cotransporter SGLT1 with High Affinity
2007
Glucose-induced serum- and glucocorticoid-regulated kinase activation in oncofetal fibronectin expression
2005
Pharmacokinetic/Pharmacodynamic Evaluation of the NHE Inhibitor Eniporide
2001
EMD273316 & EMD95833, type 4 phosphodiesterase inhibitors, stimulate fibroblastic-colony formation by bone marrow cells via direct inhibition of PDE4 and the induction of endogenous prostaglandin synthesis
2004
Inhibitors of Ischemic Preconditioning Do Not Attenuate Na+/H+ Exchange Inhibitor Mediated Cardioprotection
2000
Structure of the C-domain of Human Cardiac Troponin C in Complex with the Ca2+ Sensitizing Drug EMD 57033
2001
Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARγ agonist pioglitazone
2008
Inhibition and reversal of myocardial infarction-induced hypertrophy and heart failure by NHE-1 inhibition
2004
EMD638683, a Novel SGK Inhibitor with Antihypertensive Potency
2011
Interaction of Cardiac Troponin C with Ca2+ Sensitizer EMD 57033 and Cardiac Troponin I Inhibitory Peptide
2000
(2-Methyl-5-(methylsulfonyl)benzoyl)guanidine Na+/H+ Antiporter Inhibitors
1997
Amino acid sequence of the cyclic GMP stimulated cyclic nucleotide phosphodiesterase from bovine heart
1990
Uracil-based angiotensin II receptor antagonists
1995
Na+/H+exchange inhibition prevents endothelial dysfunction after I/R injury
2001
Bicyclic Acylguanidine Na+/H+ Antiporter Inhibitors
1998
The Novel Cardiotonic Agent EMD 53 998 is a Potent “Calcium Sensitizer”
1991
3-Substituted 6-butyl-1,2-dihydropyridin-2-ones: A new series of potent nonpeptide angiotensin II receptor antagonists
1994
A New Sodium/Hydrogen Exchange Inhibitor, EMD 85131, Limits Infarct Size in Dogs When Administered Before or After Coronary Artery Occlusion
1998