Citation Impact
Citing Papers
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Probing p53 biological functions through the use of genetically engineered mouse models
2005
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication
1991
Regulation of p53 stability by Mdm2
1997 StandoutNature
An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene
1991
Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.
1991
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
The p53 proto-oncogene can act as a suppressor of transformation
1989 Standout
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
1990 StandoutNature
How Tumors Become Angiogenic
1996
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1992 Standout
Genetic instabilities in human cancers
1998 StandoutNature
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
A genetic model for colorectal tumorigenesis
1990 Standout
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1990 Standout
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
The role of p53 in tumour suppression: lessons from mouse models
1999
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Tumor suppressor genes
1991 Standout
A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition
1988
COMMENTARY: p53 Tumor suppressor gene: from the basic research laboratory to the clinic—an abridged historical perspective
1996
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
1990
The p53 tumour suppressor gene
1991 StandoutNature
The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen
1989
T-cell antigen receptor genes and T-cell recognition
1988 StandoutNature
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
1991 StandoutNobel
p53 is required for radiation-induced apoptosis in mouse thymocytes
1993 StandoutNature
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
1997 Standout
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones
1993
The first 30 years of p53: growing ever more complex
2009 Standout
Polymerase Chain Reaction with Single-Sided Specificity: Analysis of T Cell Receptor δ Chain
1989 Science
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
1991 StandoutNobel
Structure and polymorphism of the mouse prion protein gene.
1994 StandoutNobel
p53 Mutations in Human Cancers
1991 StandoutScience
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Expression of CD4 in transgenic mice alters the specificity of CD8 cells for allogeneic major histocompatibility complex.
1991 StandoutNobel
The t(11;14)(p15;q11) in a T-Cell Acute Lymphoblastic Leukemia Cell Line Activates Multiple Transcripts, Including Ttg-1, a Gene Encoding a Potential Zinc Finger Protein
1989
High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene.
1989
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
The LIM region of a presumptive Caenorhabditis elegans transcription factor is an iron-sulfur- and zinc-containing metallodomain.
1991 StandoutNobel
Cancer Cell Cycles
1996 StandoutScience
Wild-type p53 can inhibit oncogene-mediated focus formation.
1989
Frequency and structure of p53 rearrangements in human osteosarcoma.
1990
Integration of Friend murine leukemia virus into both alleles of the p53 oncogene in an erythroleukemic cell line
1988
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.
1989
Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms
1990 StandoutScience
The outline structure of the T-cell alpha beta receptor.
1988
Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation.
1987
Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex
1986
Isolation of human‐p53‐specific monoclonal antibodies and their use in the studies of human p53 expression
1986
Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements.
1987 StandoutNobel
p53: A Frequent Target for Genetic Abnormalities in Lung Cancer
1989 StandoutScience
Viruses in Human Cancers
1991 StandoutScienceNobel
Multistage Friend erythroleukemia: independent origin of tumor clones with normal or rearranged p53 cellular oncogenes
1987
Genes of the T-Cell Antigen Receptor in Normal and Malignant T Cells
1987
Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor.
1987
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Characterization of the human p53 gene.
1986
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.
1990
Abnormal Centrosome Amplification in the Absence of p53
1996 Science
The Molecular Biology of Axon Guidance
1996 StandoutScience
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
p53 mutations increase resistance to ionizing radiation.
1993
The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.
1990
Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53
1990 StandoutScience
Genetic Mechanisms of Tumor Suppression by the Human p53 Gene
1990 Science
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53.
1992
Cytokines Inhibit p53-Mediated Apoptosis but Not p53-Mediated G1 Arrest
1995
Monoclonal antibody analysis of p53 expression in normal and transformed cells
1986
Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas
1989 StandoutScience
Mechanisms of p53 loss in human sarcomas.
1990
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
1999 StandoutNobel
Works of Nobuhiro Kimura being referenced
Sequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes.
1986
Constitutive production of granulocyte colony‐stimulating factor and interleukin‐6 by a human lung cancer cell line, KSNY: Gene amplification and increased mRNA stability
1991
Simultaneous occurrence of myelomonocytic leukemia and multiple myeloma: Involvement of common leukemic progenitors and their developmental abnormality of “lineage infidelity”
1991
Sequence and organization of the human T cell δ chain gene
1988
Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus
1985 Nature
Sequences and repertoire of the human T cell receptor α and β chain variable region genes in thymocytes
1987