Standout Papers
- Solitons in Polyacetylene: Effects of Dilute Doping on Optical Absorption Spectra (1980)
- Molecular cloning and structure of the human interleukin 2 receptor gene (1985)
- The human IL-2 receptor gene contains a positive regulatory element that functions in cultured cells and cell-free extracts. (1987)
- Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells (1991)
- Introduction of Mouse Cε Genes into Cos-7 Cells and Fertilized Mouse Eggs1 (1985)
- Behçet's Disease (1999)
- Production of sterile transcripts of Cγ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells (1989)
- Transcription of IL-2 receptor gene is stimulated by ATL-derived factor produced by HTLV-I(+) T cell lines (1987)
- Molecular mechanism for the formation of the high-affinity complex of interleukin 2 and its receptor. (1988)
- HTLV-1 p27rex stabilizes human interleukin-2 receptor alpha chain mRNA. (1990)
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene.
1991 StandoutNobel
Regulatory anatomy of the murine interleukin-2 gene
1990
G Protein-coupled Chemoattractant Receptors Regulate Lyn Tyrosine Kinase·Shc Adapter Protein Signaling Complexes
1995
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
1995 Standout
The SCID but Not the RAG-2 Gene Product Is Required for Sμ–Sε Heavy Chain Class Switching
1996
Mechanism and Regulation of Immunoglobulin Isotype Switching
1993
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Cyclophilin A Regulates TCR Signal Strength in CD4+ T Cells via a Proline-Directed Conformational Switch in Itk
2004
RalGDS is required for tumor formation in a model of skin carcinogenesis
2005
Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells
2004
The Hallmarks of Cancer
2000 Standout
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses
2004
Ablation of TrpV1 neurons reveals their selective role in thermal pain sensation
2009
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Circular DNA is excised by immunoglobulin class switch recombination
1990 StandoutNobel
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins
1997
The P2Y agonist UTP activates cutaneous afferent fibers
2004
Deconstructing cerebellar development cell by cell
2020
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
1993 StandoutNatureNobel
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
A spatially and temporally restricted mouse model of soft tissue sarcoma
2007
GEFs and GAPs: Critical Elements in the Control of Small G Proteins
2007
Interleukin-8 Regulation of the Ras/Raf/Mitogen-activated Protein Kinase Pathway in Human Neutrophils
1996
Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans
1993
Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives
2017
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
ECM and Cell Surface Proteolysis: Regulating Cellular Ecology
1997
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Ras-regulated signaling processes in Saccharomyces cerevisiae
1991
Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
2009
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Sidestream cigarette smoke accelerates atherogenesis in apolipoprotein E−/− mice
2001
Experimental studies of sodium-doped polyacetylene: Optical and ESR results for metallic (CHNay)x
1981 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
Theory of optical absorption intrans-polyacetylene containing solitons
1981
A transgenic model of autoimmune hemolytic anemia.
1992 StandoutNobel
Cooperative interactions between the interleukin 2 receptor alpha and beta chains alter the interleukin 2-binding affinity of the receptor subunits.
1994
Hot luminescence in polyacetylene
1982
Genomic organization of IgH gene compared with the expression of Bcl-2 gene in t(14;18)-positive lymphoma
1991 StandoutNobel
Infrared-active vibrational modes of charged solitons in( CH ) x ( CD ) x
1981 StandoutNobel
ESR studies of trans-(CH)x during photoexcitation
1982 StandoutNobel
PLANT DISEASE RESISTANCE GENES
1997 Standout
Solitons at high density intrans-( CH ) x
1984 StandoutNobel
Boundary conditions and optical absorption in the soliton model of polyacetylene
1982
Bilirubin conjugates of human bile. The excretion of bilirubin as the acyl glycosides of aldobiouronic acid, pseudoaldobiouronic acid and hexuronosylhexuronic acid, with a branched-chain hexuronic acid as one of the components of hexuronosylhexuronide
1970
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Semiconductor-metal transition in doped polyacetylene
1981
Opto-electrochemical spectroscopy oftrans-( CH ) x
1982 StandoutNobel
A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon.
1993
Are Adult Learning Mechanisms Also Used for Development?
1992 StandoutScienceNobel
High-affinity antibodies to ssDNA are produced by CD-B cells in systemic lupus erythematosus patients.
1989
Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins
1993 StandoutScienceNobel
A larger number of L chains (Tac) enhance the association rate of interleukin 2 to the high affinity site of the interleukin 2 receptor.
1988 StandoutNobel
Seppuku and Autoimmunity
1992 StandoutScienceNobel
Viruses in Human Cancers
1991 StandoutScienceNobel
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Inflammatory mediators and modulators of pain
2006
Signaling Specificity by Ras Family GTPases Is Determined by the Full Spectrum of Effectors They Regulate
2004
Mechanism for photogeneration of metastable charged solitons in polyacetylene
1988 StandoutNobel
Adhesion molecules and the hierarchy of neural development
1988
Magnetic susceptibility of iodine doped polyacetylene: The effects of nonuniform doping
1981 StandoutNobel
Charge storage in doped poly(thiophene): Optical and electrochemical studies
1984 StandoutNobel
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Durham poly acetylene: preparation and properties of the unoriented material
1986
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Electronic properties of junctions between silicon and organic conducting polymers
1990 StandoutNatureNobel
Differentiation of Effector CD4 T Cell Populations
2010 Standout
Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering
1987
Solitons in polyacetylene: Optical absorption in lightly doped polyacetylene
1981
Thin Films of n -Si/Poly-(CH 3 ) 3 Si-Cyclooctatetraene: Conducting-Polymer Solar Cells and Layered Structures
1990 StandoutScienceNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia
1992 StandoutScienceNobel
Works of Noboru Suzuki being referenced
Introduction of the MASH1 gene into mouse embryonic stem cells leads to differentiation of motoneuron precursors lacking Nogo receptor expression that can be applicable for transplantation to spinal cord injury
2006
Effects of Cigarette Smoking on Fas/Fas Ligand Expression of Human Lymphocytes
1999
The targeted disruption of the CD98 gene results in embryonic lethality
2003
B cell hyperactivity and its relation to distinct clinical features and the degree of disease activity in patients with systemic lupus erythematosus
1988
Characterization of a Novel Gene Product (Mammalian Tolloid-like) with High Sequence Similarity to Mammalian Tolloid/Bone Morphogenetic Protein-1
1996
Production of sterile transcripts of Cγ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells
1989 StandoutNobel
FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase.
1994
Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice
2006
CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model
2016
Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells
1991
Interleukin-2 Receptor: Structure, Function, and Expression
1986 Nobel
Crucial Role of Phospholipase Cε in Chemical Carcinogen-Induced Skin Tumor Development
2004
Biosynthesis of Branched Chain Deoxysugars
1968
The posttranslational processing of ras p21 is critical for its stimulation of yeast adenylate cyclase.
1992
Molecular cloning and structure of the human interleukin 2 receptor gene
1985 StandoutNobel
Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody
1984
Age-dependent dormant resident progenitors are stimulated by injury to regenerate Purkinje neurons
2018
Solitons in Polyacetylene: Effects of Dilute Doping on Optical Absorption Spectra
1980 StandoutNobel
Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology
2013
Txk, a Nonreceptor Tyrosine Kinase of the Tec Family, Is Expressed in T Helper Type 1 Cells and Regulates Interferon γ Production in Human T Lymphocytes
1999
Molecular mechanism for the formation of the high-affinity complex of interleukin 2 and its receptor.
1988 StandoutNobel
Isolation and Structure of Cytidine Diphosphate 6-Deoxy-3-C-methyl-2-O-methyl-l-aldohexopyranoside (Cytidine Diphosphate Vinelose) from Azotobacter vinelandii
1967
Txk, a Member of Nonreceptor Tyrosine Kinase of Tec Family, Acts as a Th1 Cell-Specific Transcription Factor and Regulates IFN-γ Gene Transcription
2002
The human IL-2 receptor gene contains a positive regulatory element that functions in cultured cells and cell-free extracts.
1987 StandoutNobel
Possible Involvement of P2Y2Metabotropic Receptors in ATP-Induced Transient Receptor Potential Vanilloid Receptor 1-Mediated Thermal Hypersensitivity
2003
The Effect of Posttranslational Modifications on the Interaction of Ras2 with Adenylyl Cyclase
1993 Science
Leucine-rich repeats and carboxyl terminus are required for interaction of yeast adenylate cyclase with RAS proteins.
1990
Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid
1996