Standout Papers
Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome
2008 StandoutScienceNobel
Structures of the Bacterial Ribosome at 3.5 A Resolution
2005 Science
Machine learning predicts new anti-CRISPR proteins
2020 StandoutNobel
PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex
2018 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis
2017 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
2019 StandoutNobel
Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing
2019
The Ribosome as a Conveying Thermal Ratchet Machine
2009
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins
2018
Piezo1 is a mechanically activated ion channel and mediates pressure induced pancreatitis
2018
Redox regulation of the hypoxia-inducible factor
2006
Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1
2017
Structural insights into the inactivation of CRISPR-Cas systems by diverse anti-CRISPR proteins
2018
Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a
2019 StandoutNobel
Unravelling biological macromolecules with cryo-electron microscopy
2016 Nature
Paradigms of ribosome synthesis: Lessons learned from ribosomal proteins
2014
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Unsupervised classification of single particles by cluster tracking in multi-dimensional space
2006 StandoutNobel
mRNA translocation occurs during the second step of ribosomal intersubunit rotation
2011
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease
2016
Mutations in the Intersubunit Bridge Regions of 23 S rRNA
2006
Protein-protected luminescent noble metal quantum clusters: an emerging trend in atomic cluster nanoscience
2012
Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a
2017
Comprehensive Molecular Structure of the Eukaryotic Ribosome
2009 StandoutNobel
Dawning of a new era in TRP channel structural biology by cryo-electron microscopy
2018
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins
2019
Mechanism of eIF6 release from the nascent 60S ribosomal subunit
2015
Diversity, classification and evolution of CRISPR-Cas systems
2017
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia coli
2011
Single-molecule observations of ribosome function
2009
Biological mechanisms, one molecule at a time
2011
Gold nanoclusters as novel optical probes for in vitro and in vivo fluorescence imaging
2012
A fast dynamic mode of the EF‐G‐bound ribosome
2009
The Role of PIEZO2 in Human Mechanosensation
2016
Diversity and evolution of class 2 CRISPR–Cas systems
2017
Recycling of Eukaryotic Posttermination Ribosomal Complexes
2007
Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy
2008 StandoutNobel
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
A structural understanding of the dynamic ribosome machine
2008 StandoutNobel
Intermediate states during mRNA–tRNA translocation
2012 StandoutNobel
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Structural dynamics of the ribosome
2008
Navigating the ribosome's metastable energy landscape
2009
Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins
2019
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S subunit
2016
Eukaryote-specific rRNA expansion segments function in ribosome biogenesis
2016
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy
2012 StandoutNobel
Microwave-assisted synthesis of BSA-protected small gold nanoclusters and their fluorescence-enhanced sensing of silver(i) ions
2012
Mechanistic insight into eukaryotic 60S ribosomal subunit biogenesis by cryo-electron microscopy
2016
Observation of Intersubunit Movement of the Ribosome in Solution Using FRET
2007
Different sized luminescent gold nanoparticles
2012
Anti-CRISPR: discovery, mechanism and function
2017
Visualization of the Hybrid State of tRNA Binding Promoted by Spontaneous Ratcheting of the Ribosome
2008 StandoutNobel
Distribution of dwell times of a ribosome: effects of infidelity, kinetic proofreading and ribosome crowding
2011
Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
2009 StandoutNobel
60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle
2014
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
2019 StandoutNobel
ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps
2018
Spontaneous Intersubunit Rotation in Single Ribosomes
2008
Transfer RNA–mediated regulation of ribosome dynamics during protein synthesis
2011
Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome
2011
The Role of L1 Stalk–tRNA Interaction in the Ribosome Elongation Cycle
2010
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu
2009 StandoutNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu binding
2010
Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization
2017 StandoutNobel
A hierarchical model for assembly of eukaryotic 60S ribosomal subunit domains
2014
The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit
2017
Inhibition of Type III CRISPR-Cas Immunity by an Archaeal Virus-Encoded Anti-CRISPR Protein
2019
Deletion of a Conserved, Central Ribosomal Intersubunit RNA Bridge
2006
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
The Role of ABCE1 in Eukaryotic Posttermination Ribosomal Recycling
2010
Unraveling the dynamics of ribosome translocation
2012
Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a
2019
Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation
2015
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states
2017
Anti-CRISPR-Associated Proteins Are Crucial Repressors of Anti-CRISPR Transcription
2019
Meet the Anti-CRISPRs: Widespread Protein Inhibitors of CRISPR-Cas Systems
2019
Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome
2010 StandoutNobel
The structure of LepA, the ribosomal back translocase
2008 StandoutNobel
Gain‐of‐function mutations in PIEZO1 directly impair hepatic iron metabolism via the inhibition of the BMP/SMADs pathway
2019
Structures of the Ribosome in Intermediate States of Ratcheting
2009 Science
The mechanosensitive Piezo1 channel is required for bone formation
2019
Structural characterization of mRNA-tRNA translocation intermediates
2012 StandoutNobel
Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding
2011 Science
Functions of Ribosomal Proteins in Assembly of Eukaryotic Ribosomes In Vivo
2015
Spontaneous formation of the unlocked state of the ribosome is a multistep process
2009
Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM
2008 StandoutNobel
Quantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome
2015 StandoutNobel
Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G
2015 StandoutNobel
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
Ribosomal Translocation: One Step Closer to the Molecular Mechanism
2009
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Eukaryotic DNA Replication Fork
2017
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Nanomolar Hg2+ Detection Using β-Lactoglobulin-Stabilized Fluorescent Gold Nanoclusters in Beverage and Biological Media
2016
How Should We Think About the Ribosome?
2012
Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein
2017
Ultrasmall metal nanoclusters for bio‐related applications
2013
Trajectories of the ribosome as a Brownian nanomachine
2014 StandoutNobel
Intracellular Thermometry by Using Fluorescent Gold Nanoclusters
2013
Formation of fluorescent platinum nanoclusters using hyper-branched polyethylenimine and their conjugation to antibodies for bio-imaging
2016
Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release
2016
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Anti‐CRISPRs: The natural inhibitors for CRISPR‐Cas systems
2019
RIBOSOME DYNAMICS: Insights from Atomic Structure Modeling into Cryo-Electron Microscopy Maps
2006 StandoutNobel
Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex
2012 StandoutNobel
The ribosome uses cooperative conformational changes to maximize and regulate the efficiency of translation
2014
Ribosome Structure and Dynamics During Translocation and Termination
2010
Shortwave Infrared in Vivo Imaging with Gold Nanoclusters
2017 StandoutNobel
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation
2011 StandoutNobel
PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures
2018
Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit
2016 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Functionalization of metal nanoclusters for biomedical applications
2016
Functionally diverse type V CRISPR-Cas systems
2018 Science
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Fabrication of Transferrin Functionalized Gold Nanoclusters/Graphene Oxide Nanocomposite for Turn-On Near-Infrared Fluorescent Bioimaging of Cancer Cells and Small Animals
2013
Atomically Precise Clusters of Noble Metals: Emerging Link between Atoms and Nanoparticles
2017 Standout
Story in a sample—the potential (and limitations) of cryo‐electron microscopy applied to molecular machines
2013 StandoutNobel
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation
2009
Works of Ning Gao being referenced
The crystal structure of Cpf1 in complex with CRISPR RNA
2016 Nature
p38 Signaling-mediated Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor Induction by Cr(VI) in DU145 Human Prostate Carcinoma Cells
2002
Structural basis for interaction of a cotranslational chaperone with the eukaryotic ribosome
2014
Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
2016 Nature
Structure of the eukaryotic MCM complex at 3.8 Å
2015 Nature
Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
2013
Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
2017
Mechanism for the Disassembly of the Posttermination Complex Inferred from Cryo-EM Studies
2005 StandoutNobel
The N-terminal extension of yeast ribosomal protein L8 is involved in two major remodeling events during late nuclear stages of 60S ribosomal subunit assembly
2016
An anti-CRISPR protein disables type V Cas12a by acetylation
2019
Vanadate-induced Expression of Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor through Phosphatidylinositol 3-Kinase/Akt Pathway and Reactive Oxygen Species
2002
Specific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into Subunits
2007 StandoutNobel
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
2012
Architecture of the mammalian mechanosensitive Piezo1 channel
2015 Nature
Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures
2017
Arsenite induces HIF-1α and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells
2003
Fine-Tuned H-Ferritin Nanocage with Multiple Gold Clusters as Near-Infrared Kidney Specific Targeting Nanoprobe
2015
Controlling Assembly of Paired Gold Clusters within Apoferritin Nanoreactor for in Vivo Kidney Targeting and Biomedical Imaging
2011
Structural dynamics of the yeast Shwachman-Diamond syndrome protein (Sdo1) on the ribosome and its implication in the 60S subunit maturation
2016
The process of mRNA–tRNA translocation
2007 StandoutNobel