Citation Impact
Citing Papers
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Nonshivering thermogenesis and its adequate measurement in metabolic studies
2010
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
Cold-Activated Brown Adipose Tissue in Healthy Men
2009 Standout
Cardiovascular and Metabolic Alterations in Mice Lacking Both β1- and β2-Adrenergic Receptors
1999 StandoutNobel
Halothane Selectively Inhibits Nonshivering Thermogenesis
1995
Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT1B receptor
1999
Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line
1994
Norepinephrine Increases Glucose Transport in Brown Adipocytes via β3-Adrenoceptors through a cAMP, PKA, and PI3-Kinase-Dependent Pathway Stimulating Conventional and Novel PKCs
2003
β-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase Iα Promotes Agonist-stimulated Sequestration of the β2-Adrenergic Receptor
2008 StandoutNobel
Selective Up-Regulation of α1a-Adrenergic Receptor Protein and mRNA in Brown Adipose Tissue by Neural and β3-Adrenergic Stimulation
1997
Identification and Importance of Brown Adipose Tissue in Adult Humans
2009 Standout
Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons
2000 StandoutNobel
Analysis of inhibition by H89 of UCP1 gene expression and thermogenesis indicates protein kinase A mediation of β3-adrenergic signalling rather than β3-adrenoceptor antagonism by H89
2001
Role for ELOVL3 and Fatty Acid Chain Length in Development of Hair and Skin Function
2004 StandoutNobel
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
β3- and α1-Adrenergic Erk1/2 Activation Is Src- but Not Gi-mediated in Brown Adipocytes
2000
β3 and Atypical β‐Adrenoceptors
1993
ELOVL3 Is an Important Component for Early Onset of Lipid Recruitment in Brown Adipose Tissue
2005 StandoutNobel
α1- and β-Adrenergic regulation of intracellular Ca2+ levels in brown adipocytes
1989
UCP1 is essential for adaptive adrenergic nonshivering thermogenesis
2006
Identification of an Allosteric Binding Site for Zn2+on the β2 Adrenergic Receptor
2002 StandoutNobel
Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1α: implications for development of selective CXCR4 antagonists
2001
Palladium‐Catalyzed Carbonylation Reactions of Aryl Halides and Related Compounds
2009
Unexpected evidence for active brown adipose tissue in adult humans
2007 Standout
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
1998 Standout
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Novel dopamine receptors half a decade later
1995
UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency
2001
Functional Brown Adipose Tissue in Healthy Adults
2009 Standout
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Brown adipose tissue thermogenesis and obesity
1989
Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids
2004
[18F]FMeNER-D2: Reliable fully-automated synthesis for visualization of the norepinephrine transporter
2013
A distributional code for value in dopamine-based reinforcement learning
2020 StandoutNatureNobel
α1-Adrenergic Stimulation Potentiates the Thermogenic Action of β3-Adrenoreceptor-generated cAMP in Brown Fat Cells
1997
Norepinephrine Induces Vascular Endothelial Growth Factor Gene Expression in Brown Adipocytes through a β-Adrenoreceptor/cAMP/Protein Kinase A Pathway Involving Src but Independently of Erk1/2
2000
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
α1‐Adrenergic stimulation of Cl− efflux in isolated brown adipocytes
1990
Metabolic response to various β‐adrenoceptor agonists in β3‐adrenoceptor knockout mice: Evidence for a new β‐adrenergic receptor in brown adipose tissue
1998
Down-regulation of β3 Adrenoreceptor Gene Expression in Brown Fat Cells Is Transient and Recovery Is Dependent upon a Short-lived Protein Factor
1996
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Differential activation of β1‐, β2‐ and β3‐adrenoceptors by catecholamines in white and brown adipocytes
1995
Expression of nerve growth factor in brown adipose tissue: implications for thermogenesis and obesity.
1996
Ambient Temperature Regulation of Apoptosis in Brown Adipose Tissue
1998
A review of central 5-HT receptors and their function
1999 Standout
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Effects of insulin and norepinephrine on glucose transport and metabolism in rat brown adipocytes
1987
What We Talk About When We Talk About Fat
2014 Standout
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
2007
A Potential Role for Adenosine in the Inhibition of Nonshivering Thermogenesis in the Fetal Sheep
1995
A Dual Component Analysis Explains the Distinctive Kinetics of cAMP Accumulation in Brown Adipocytes
1999
Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice
2003 StandoutNobel
Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules
2006
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Nitric Oxide and Thermogenic Function of Brown Adipose Tissue in Rats.
2000
Pharmacological characterization of CGP 12177 at the human β2‐adrenoceptor
2002
Control of β3-adrenergic receptor gene expression in brown adipocytes in culture
1995
α1- and β-Adrenergic Agents Cause Synergistic Stimulation of the Iodothyronine Deiodinase in Rat Brown Adipocytes*
1989
Thermogenic Responses in Brown Fat Cells Are Fully UCP1-dependent
2000
Uncoupling protein mRNA, mitochondrial GTP-binding, and T4 5′-deiodinase activity of brown adipose tissue in Daurian ground squirrel during hibernation and arousal
1998
Dopaminergic activities in the human striatum: rostrocaudal gradients of uptake sites and of D1 and D2 but not of D3 receptor binding or dopamine
1999
Dopamine receptors: Molecular biology, biochemistry and behavioural aspects
1994
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway
1999 StandoutNobel
Brown Adipose Tissue in Adult Humans: A Metabolic Renaissance
2013
Iron Catalysis in Organic Synthesis
2015 Standout
Parallel increases in amount of (3H)GDP binding and thermogenin antigen in brown-adipose-tissue mitochondria of cafeteria-fed rats
1984
The Golden Age of Transfer Hydrogenation
2015 Standout
Alpha- and beta-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture.
1990
Over One Hundred Peptide-Activated G Protein-Coupled Receptors Recognize Ligands with Turn Structure
2005
Regulation of expression of the lipoprotein lipase gene in brown adipose tissue
1992
β-Adrenergic potentiation of endoplasmic reticulum Ca2+release in brown fat cells
2002
βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance
2002 StandoutScienceNobel
Beta-adrenergic, cAMP-mediated stimulation of proliferation of brown fat cells in primary culture. Mediation via beta 1 but not via beta 3 adrenoceptors.
1992
Gold(I)-catalyzed benzannulation of 3-hydroxy-1,5-enynes: an efficient synthesis of substituted tetrahydronaphthalenes and related compounds
2007
Stimulation of phosphoinositide metabolism in hamster brown adipocytes exposed to α1-adrenergic agents and its inhibition with phorbol esters
1986
Norepinephrine-induced sustained inward current in brown fat cells: α1-mediated by nonselective cation channels
2000
Pharmacological Approaches for the Treatment of Obesity
2002
Differential adrenergic regulation of the gene expression of the β-adrenoceptor subtypes β1, β2 and β3 in brown adipocytes
2000
Impact of animal handling on the results of 18F-FDG PET studies in mice.
2006
Expressed α1-adrenoceptors in adult rat brown adipocytes are primarily of α1Asubtype
1996
Aporphine Alkaloid Synthesis and Diversification via Direct Arylation
2006
Increased alpha 1-adrenoceptor density in brown adipose tissue indicates recruitment drive in hypothyroid rats
1992
Carbon−Carbon Coupling Reactions Catalyzed by Heterogeneous Palladium Catalysts
2006 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Alpha 1-adrenergic stimulation of hamster brown adipocyte respiration
1983
Thermogenesis Inhibition in Brown Adipocytes Is a Specific Property of Volatile Anesthetics
2003
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
The Brown Fat Cell
1982
Towards More Effective Antipsychotic Treatment
1994
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.
1987 StandoutNobel
Hormone-sensitive lipase in brown adipose tissue: Identification and effect of cold exposure
1987
Cig30, a Mouse Member of a Novel Membrane Protein Gene Family, Is Involved in the Recruitment of Brown Adipose Tissue
1997
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Cold-induced reduction in Giα proteins in brown adipose tissue. Effects on the cellular hypersensitization to noradrenaline caused by pertussis-toxin treatment
1996
G Protein Activation by Human Dopamine D3 Receptors in High-Expressing Chinese Hamster Ovary Cells: A Guanosine-5′-O-(3-[35S]thio)-Triphosphate Binding and Antibody Study
1999
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
A paradoxical regulation of the dopamine D3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons.
1995
Phorbol esters inhibit alpha 1-adrenergic effects and decrease the affinity of liver cell alpha 1-adrenergic receptors for (-)-epinephrine.
1986
β-adrenergic stimulation of fatty acid release from brown fat cells differentiated in monolayer culture
1986
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
2009 Standout
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Thyroid-catecholamine interactions in isolated rat brown adipocytes
1984
Structure, Function, and Regulation of the Three β‐Adrenergic Receptors
1995
Stereoselective Cyclopropanation Reactions
2003 Standout
Computational Elucidation of the Structural Basis of Ligand Binding to the Dopamine 3 Receptor through Docking and Homology Modeling
2006
Norepinephrine-induced Na+ influx in brown adipocytes is cyclic AMP-mediated.
1986
Phorbol esters, protein kinase C, and thyroxine 5'-deiodinase in brown adipocytes
1988
Catalytic Cyclopropanation of Alkenes Using Diazo Compounds Generated in Situ. A Novel Route to 2-Arylcyclopropylamines
2001
Role of β1- and β3-adrenoceptors in the regulation of lipolysis and thermogenesis in rat brown adipocytes
1997
β1 to β3 Switch in Control of Cyclic Adenosine Monophosphate during Brown Adipocyte Development Explains Distinct β-Adrenoceptor Subtype Mediation of Proliferation and Differentiation1
1999
Molecular characterization of the mouse beta 3-adrenergic receptor: relationship with the atypical receptor of adipocytes.
1991
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
Effects of Cations on Brown Adipose Tissue in Relation to Possible Metabolic Consequences of Membrane Depolarisation
1981
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
2012 Standout
Asymmetric reduction of methoxy substituted β-tetralones using transfer hydrogenation
2004
Changes in adrenoreceptor density in brown adipose tissue from hyperthyroid rats
1985
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Activities of enzymes of glycerolipid synthesis in brown adipose tissue after treatment of rats with the adrenergic agonists BRL 26830A and phenylephrine, after exposure to cold and in streptozotocin-diabetes
1991
Metabolic effects of β, α1, and α2 adrenoceptor activation on brown adipocytes isolated from the perirenal adipose tissue of fetal lambs
1984
beta1-adrenergic receptors mediate beta3-adrenergic-independent effects of CGP 12177 in brown adipose tissue.
2000
α1‐Adrenergic activation of brown adipocytes leads to an increased formation of inositol polyphosphates
1986
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Potassium channel block does not affect metabolic responses of brown fat cells
1992
Coexisting beta-adrenoceptor subtypes: significance for thermogenic process in brown fat cells
1994
Iron-Catalyzed Cross-Coupling of Imidoyl Chlorides with Grignard Reagents
2006
The Binding Site of Aminergic G Protein–Coupled Receptors: The Transmembrane Segments and Second Extracellular Loop
2002
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Direct C−H Transformation via Iron Catalysis
2010 Standout
Immunohistochemical evidence for the existence of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in brown adipose tissue of pigs.
1988
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Fat cell adrenergic receptors and the control of white and brown fat cell function
1993
ATP synthase subunit c expression: physiological regulation of the P1 and P2 genes
1997
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Norepinephrine utilizes alpha 1- and beta-adrenoreceptors synergistically to maximally induce c-fos expression in brown adipocytes
1994
The putative β4-adrenergic receptor is a novel state of the β1-adrenergic receptor
2001
Dopamine Receptors: From Structure to Function
1998 Standout
Presence of a Ca2+-dependent K+ channel in brown adipocytes. Possible role in maintenance ofα1-adrenergic stimulation
1985
Why are there so many adrenoceptor subtypes?
1994
Differential regulation of the expression of α1-adrenergic receptor subtype genes in brown adipose tissue
1997
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Apparent thermogenic effect of injected glucagon is not due to a direct effect on brown fat cells
1998
Apparent absence of alpha-2 adrenergic receptors from hamster brown adipocytes
1982
Works of Nina Mohell being referenced
Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors.
1994
Alpha 1-adrenergic stimulation of phosphatidylinositol turnover and respiration of brown fat cells.
1984
Comparison of the pharmacological profiles of adrenergic drugs (Including BRL-agonists) at [3H]prazosin and [3H]CGP-12177 binding sites in brown adipose tissue
1989
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine
2004
Derivatives of cis-2-Amino-8-hydroxy-1-methyltetralin: Mixed 5-HT1A-Receptor Agonists and Dopamine D2-Receptor Antagonists
1995
Interactions of ligands with active and inactive conformations of the dopamine D2 receptor
1998
Serotonergic and dopaminergic activities of rigidified (R)-aporphine derivatives
2001
Inhibitory effects of halothane on the thermogenic pathway in brown adipocytes: localization to adenylyl cyclase and mitochondrial fatty acid oxidation
2004
Site-directed mutagenesis of the 5-HT1B receptor increases the affinity of 5-HT for the agonist low-affinity conformation and reduces the intrinsic activity of 5-HT
2001
Thermogenesis in Brown Adipocytes Is Inhibited by Volatile Anesthetic Agents A Factor Contributing to Hypothermia in Infants?
1994
Cold acclimation induces desensitization to adenosine in brown fat cells without changing receptor binding
1990
Requirement of gene transcription and protein synthesis for cold-and norepinephrine-induced stimulation of thyroxine deiodinase in rat brown adipose tissue
1986
Distinction between mechanisms underlying alpha 1- and beta-adrenergic respiratory stimulation in brown fat cells
1987
Synthesis of Novel 5-Substituted 3-Amino-3,4-dihydro-2H-1-benzopyran Derivatives and Their Interactions with the 5-HT1A Receptor
2000
Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors.
1995
Derivatives of 2-arylcyclopropylamine: Synthesis and interactions with 5-HT1A receptors.
1996
Characterization of [3H]Dihydroergocryptine Binding Sites in Brown Adipose Tissue. Evidence for the Presence of alpha-Adrenergic Receptors.
1980
Increased α1-adrenergic receptor density in brown adipose tissue of cold-acclimated rats and hamsters
1984
The Pharmacological Characterization of a Novel Selective 5-Hydroxytryptamine1A Receptor Antagonist, NAD-299
1997
Increased α1 receptor density in brown adipose tissue of cafeteria-fed rats
1984
A possible physiological role of the Na+/Ca2+ exchange mechanism of brown-fat mitochondria in the mediation of α1-adrenergic signals
1984
Discovery of the First Nonpeptide Agonist of the GPR14/Urotensin-II Receptor: 3-(4-Chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954)
2002
Novel 2-Aminotetralin and 3-AminoChroman Derivatives as Selective Serotonin 5-HT7 Receptor Agonists and Antagonists
2004
The β-adrenergic radioligand [3H]CGP-12177, generally classified as an antagonist, is a thermogenic agonist in brown adipose tissue
1989
Agonist and inverse agonist activity at the dopamine D3 receptor measured by guanosine 5'--gamma-thio-triphosphate--35S- binding.
1998
Alpha 1-adrenergic receptors in brown adipose tissue. Thermogenic significance and mode of action.
1984
Quantitative differentiation of α- and β-adrenergic respiratory responses in isolated hamster brown fat cells: Evidence for the presence of an α1-adrenergic component
1983
Physiological desensitization of beta 3-adrenergic responses in brown fat cells: involvement of a postreceptor process
1993
β3-adremergic regulation of hamster brown adipocyte thermogenesis
1990
Agonist and Inverse Agonist Activity at the Dopamine D3 Receptor Measured by Guanosine 5′-[γ-Thio]Triphosphate-[35S] Binding
1998
Identification of [3H]prazosin binding sites in crude membranes and isolated cells of brown adipose tissue as α1-adrenergic receptors
1983
Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors.
1993