Standout Papers

Estrogen Receptors: How Do They Signal and What Are Their Targets 2007 2026 2013 2019 1.4k
  1. Estrogen Receptors: How Do They Signal and What Are Their Targets (2007)
    Nina Heldring, A.C.W. Pike et al. Physiological Reviews

Citation Impact

Citing Papers

NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
2010 StandoutNobel
Tumor Repressive Functions of Estrogen Receptor β in SW480 Colon Cancer Cells
2009
MSC Therapies for COVID-19: Importance of Patient Coagulopathy, Thromboprophylaxis, Cell Product Quality and Mode of Delivery for Treatment Safety and Efficacy
2020
Estrogen receptor mutations and their role in breast cancer progression
2014
Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues
2008
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: Focus on the role and impact of proteoglycans
2013
Myeloid-derived suppressor cells coming of age
2018 Standout
Transcriptional architecture of the mammalian circadian clock
2016 Standout
G9a inhibition induced PKM2 regulates autophagic responses
2016
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’
2014
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Identification of a Hormone-regulated Dynamic Nuclear Actin Network Associated with Estrogen Receptor α in Human Breast Cancer Cell Nuclei
2010
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Extracellular vesicles for drug delivery
2016
Instructive Roles of Extracellular Matrix on Autophagy
2014
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
2017
Extracellular Vesicles and a Novel Form of Communication in the Brain
2016
An overview of chemical additives present in plastics: Migration, release, fate and environmental impact during their use, disposal and recycling
2017 Standout
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury
2017
Nuclear receptor coregulators as a new paradigm for therapeutic targeting
2010
Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application
2014
SIN3A, Generally Regarded as a Transcriptional Repressor, Is Required for Induction of Gene Transcription by the Aryl Hydrocarbon Receptor
2014
Shared Principles in NF-κB Signaling
2008 Standout
Cross-talk between nuclear receptors and nuclear factor κB
2006
Hallmarks of aging: An expanding universe
2023 Standout
Sex differences in immune responses to infectious diseases
2015
Endocrine disruption of oestrogen action and female reproductive tract cancers
2013
Endocrine disrupting chemicals and disease susceptibility
2011
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Perimenopause as a neurological transition state
2015
Development of Extracellular Vesicle Therapeutics: Challenges, Considerations, and Opportunities
2021
Response of adult mouse uterus to early disruption of estrogen receptor-α signaling is influenced by Krüppel-like factor 9
2010
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
2021 StandoutNobel
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Respiratory virus shedding in exhaled breath and efficacy of face masks
2020 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Extracellular matrix structure
2015 Standout
Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy
2017
Estrogen receptors regulate innate immune cells and signaling pathways
2015
Using exosomes, naturally-equipped nanocarriers, for drug delivery
2015
Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes
2011 StandoutNobel
Bisphenol-A: a new diabetogenic factor?
2010
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs
2014
AhR and ARNT modulate ER signaling
2009
Key Strategies for Clinical Management and Improvement of Healthcare Services for Cardiovascular Disease and Diabetes Patients in the Coronavirus (COVID-19) Settings: Recommendations From the REPROGRAM Consortium
2020
Emerging Biological Principles of Metastasis
2017 Standout
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Effects of estrogenic compounds on neonatal oocyte development
2012
Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment
2018
Aerobic Iron‐Based Cross‐Dehydrogenative Coupling Enables Efficient Diversity‐Oriented Synthesis of Coumestrol‐Based Selective Estrogen Receptor Modulators
2013
Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways
2011
Survey of the year 2003 commercial optical biosensor literature
2004
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Targeting autophagy in cancer
2017 Standout
Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins
2012 StandoutNobel
Sex differences in immune responses
2016 Standout
Caloric restriction mimetics: towards a molecular definition
2014
Introduction to NF-κB: players, pathways, perspectives
2006 Standout
Survey of the year 2005 commercial optical biosensor literature
2006
The multifaceted role of mesenchymal stem cells in cancer
2019
RNA delivery by extracellular vesicles in mammalian cells and its applications
2020
Ligand and Receptor Dynamics Contribute to the Mechanism of Graded PPARγ Agonism
2012
Environmental pollutants and type 2 diabetes: a review of mechanisms that can disrupt beta cell function
2011
The evolving translational potential of small extracellular vesicles in cancer
2020
Induced protein degradation: an emerging drug discovery paradigm
2016
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Disentangling the Many Layers of Eukaryotic Transcriptional Regulation
2012
Estrogen negatively regulates epithelial wound healing and protective lipid mediator circuits in the cornea
2011
Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
2016 Standout
Delivery of an Artificial Transcription Regulator dCas9-VPR by Extracellular Vesicles for Therapeutic Gene Activation
2018
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer
2023 StandoutNobel
Granulocytic myeloid‐derived suppressor cells from human cord blood modulate T‐helper cell response towards an anti‐inflammatory phenotype
2017
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Optimization of cisplatin for the treatment of hormone-dependent tumoral diseases
2009
Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERα-deficient mice
2009
Macrocyclic Control in Helix Mimetics
2019
Going live with tumor exosomes and microvesicles
2017
Spermidine in health and disease
2018 StandoutScience
Contributions of Amino Acid Side Chains to the Kinetics and Thermodynamics of the Bivalent Binding of Protein L to Ig κ Light Chain
2004 StandoutNobel
Thyroid Hormone Regulation of Metabolism
2014 Standout
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
The Biology of Cancer Exosomes: Insights and New Perspectives
2017
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Optimization of cisplatin for the treatment of hormone dependent tumoral diseases
2009
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Acetylation in the regulation of autophagy
2022
Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
2015 Science
Fair Allocation of Scarce Medical Resources in the Time of Covid-19
2020 Standout
Persistently Altered Epigenetic Marks in the Mouse Uterus After Neonatal Estrogen Exposure
2013

Works of Nina Heldring being referenced

Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
Cracking the survival code
2014
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
2019
Structural Insights into Corepressor Recognition by Antagonist-bound Estrogen Receptors
2007
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
2013 Nature
Notch induces cyclin-D1-dependent proliferation during a specific temporal window of neural differentiation in ES cells
2010
Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles
2015
Delineation of a unique protein–protein interaction site on the surface of the estrogen receptor
2005
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
2015
Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?
2014
Co-planar 3,3′,4,4′,5-pentachlorinated biphenyl and non-co-planar 2,2′,4,6,6′-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor α to aryl hydrocarbon receptor target genes
2007
Subtle Side-Chain Modifications of the Hop Phytoestrogen 8-Prenylnaringenin Result in Distinct Agonist/Antagonist Activity Profiles for Estrogen Receptors α and β
2006
Multiple Sequence-Specific DNA-Binding Proteins Mediate Estrogen Receptor Signaling through a Tethering Pathway
2011
Identification of Tamoxifen-Induced Coregulator Interaction Surfaces within the Ligand-Binding Domain of Estrogen Receptors
2004
Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression
2016
Rankless by CCL
2026