Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila
1995 Science
Hallmarks of Cancer: The Next Generation
2011 Standout
Expression of the T-box gene Eomesodermin during early mouse development
1999
Retinoic acid and craniofacial development: Molecules and morphogenesis
1993
Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube
1995
Position, guidance, and mapping in the developing visual system
1993
Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
1996 Nature
T-Brain-1: A homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex
1995
Maintenance of functional equivalence during paralogous Hox gene evolution
2000 StandoutNatureNobel
Interactions of Eph-related receptors and ligands confer rostrocaudal pattern to trunk neural crest migration
1997
Patterning the Brain of the Zebrafish Embryo
1993
Conservation and divergence of axon guidance mechanisms
1999
Expression cloning of Siamois, a xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis
1995 StandoutNobel
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner
2000
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Genetic Ablation and Restoration of the Olfactory Topographic Map
2000 StandoutNobel
Excitatory Eph receptors and adhesive ephrin ligands
2001
The generation of diversity and pattern in animal development
1992 StandoutNobel
If birds can fly, why can't we? Homeotic genes and evolution
1994
Temporal and Spatial Effects of Sonic Hedgehog Signaling in Chick Eye Morphogenesis
2001
Pattern formation in the vertebrate neural plate
1994
Induction and patterning of the vertebrate nervous system
1995
Guidance of Circumferentially Growing Axons by Netrin-Dependent and -Independent Floor Plate Chemotropism in the Vertebrate Brain
1996
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
1996 StandoutNature
Neural-Tube Defects
1999 Standout
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Pax2 contributes to inner ear patterning and optic nerve trajectory
1996
Induction of a specific muscle cell type by a hedgehog-like protein in zebrafish
1996 Nature
The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
1998 StandoutNobel
Characterization of a cell line derived from zebrafish (brachydanio rerio) embryos
1993
Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development
1991
The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family
2000 StandoutNobel
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
EphA receptors and ephrin-A ligands exhibit highly regulated spatial and temporal expression patterns in the developing olfactory system
2002
Regionalized metabolic activity establishes boundaries of retinoic acid signalling
1998
Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis
1996
Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses
1998
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
1994 Standout
Odorant Receptors Govern the Formation of a Precise Topographic Map
1998 StandoutNobel
Stages of embryonic development of the zebrafish
1995 Standout
Roles for Ephrins in Positionally Selective Synaptogenesis between Motor Neurons and Muscle Fibers
2000
Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
2000 Nature
Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
1995 StandoutNatureNobel
Regulation of vertebrate neural cell fate by transcription factors
1996
Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity
1992 Nature
The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells
1997
Reversal of axonal pathways from rhombomere 3 correlates with extra hox expression domains
1993
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
Hox genes and pattern formation in the branchial region of the vertebrate head
1993
Topographically Specific Effects of ELF-1 on Retinal Axon Guidance In Vitro and Retinal Axon Mapping In Vivo
1996
PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects
1994 Standout
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
1994
Homeobox genes and axial patterning
1992 Standout
Modulation of EphA Receptor Function by Coexpressed EphrinA Ligands on Retinal Ganglion Cell Axons
1999
Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development
1996
Drosophila Clock Can Generate Ectopic Circadian Clocks
2003 StandoutNobel
Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development
1999
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions
1994 StandoutNatureNobel
Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System
1996
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain
1995
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
2010
Pax proteins and eye development
1996
Angiogenic Signalling Pathways
2008
Fibroblast Growth Factors as Multifunctional Signaling Factors
1998
Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate
1993
Homeodomain-DNA recognition
1994 StandoutNobel
Function for Hedgehog Genes in Zebrafish Retinal Development
2000
Multiple roles of eph receptors and ephrins in neural development
2001
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development
1994 StandoutNobel
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
1996 Standout
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
1993 Standout
Regulation of Left–Right Asymmetries in the Zebrafish by Shh and BMP4
1999
Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases
1994
Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling
1997
The zebrafish Nodal signal Squint functions as a morphogen
2001 Nature
Hox genes in vertebrate development
1994 Standout
Ephrin-A5 (AL-1/RAGS) Is Essential for Proper Retinal Axon Guidance and Topographic Mapping in the Mammalian Visual System
1998
RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome
2008
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Eph Family Transmembrane Ligands Can Mediate Repulsive Guidance of Trunk Neural Crest Migration and Motor Axon Outgrowth
1997
Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39
1993 StandoutNobel
Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4
1998 Standout
Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor DCC
1997
Topographic Mapping in Dorsoventral Axis of the Xenopus Retinotectal System Depends on Signaling through Ephrin-B Ligands
2002
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
1994 StandoutNatureNobel
Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation
1993
Distal Regeneration and Symmetry
1981 Science
Hox Genes and Regionalization of the Nervous System
1994
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis
1992
The mouse Pax2 1Neu mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney
1996
Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning
1999
Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.
1993
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes.
1995 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Distal regeneration in proximal fragments of the wing disc of Drosophila.
1980
Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene.
1993
GROWTH CONE GUIDANCE: First Steps Towards a Deeper Understanding
1999
Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo.
1996
Regulation of retinal ganglion cell production by Sonic hedgehog
2001
Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors
1997 StandoutScience
Patterning the Vertebrate Neuraxis
1996 Science
Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.
1996
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.
1991
A role for the EphA family in the topographic targeting of vomeronasal axons
2001
Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant, kreisler (kr)
1993
Stereotyped pathway selection by growth cones of early epiphysial neurons in the embryonic zebrafish
1991
Control of chick tectum territory along dorsoventral axis by Sonic hedgehog
2000
Induction and patterning of the neural plate
1992
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Neural Science
2000 StandoutNobel
The development of a simple scaffold of axon tracts in the brain of the embryonic zebrafish, Brachydanio rerio
1990
Nodal signaling patterns the organizer
2000
A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve
1999
Regionalization within the mammalian telencephalon is mediated by changes in responsiveness to Sonic Hedgehog
1998
Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins
2000 StandoutNobel
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Molecular Development of Sensory Maps
1999
Chimeric analysis of T (Brachyury) gene function
1993
Imaging the glycome
2008 StandoutNobel
Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate
1998 StandoutNobel
Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo
1992
Identification of a retinoic acid response element upstream of the murine Hox-4.2 gene.
1993
Xwnt-11: a maternally expressed Xenopus wnt gene
1993
Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene
1996
THE EPHRINS AND EPH RECEPTORS IN NEURAL DEVELOPMENT
1998
Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch
1998
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Diversity and Pattern in the Developing Spinal Cord
1996 Science
Cooperation of Pax2 and Pax5 in midbrain and cerebellum development
1997
A Transient Population of Neurons Pioneers the Olfactory Pathway in the Zebrafish
1998
Finite Scale of Spatial Representation in the Hippocampus
2008 StandoutScienceNobel
The VAB-1 Eph Receptor Tyrosine Kinase Functions in Neural and Epithelial Morphogenesis in C. elegans
1998
Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain
1996 Nobel
The expression and regulation of chick EphA7 suggests roles in limb patterning and innervation
1998
Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning
1998
Morphogen gradient interpretation
2001 StandoutNatureNobel
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
MOLECULAR GRADIENTS AND DEVELOPMENT OF RETINOTOPIC MAPS
2005
Works of Nigel Holder being referenced
Eph signaling is required for segmentation and differentiation of the somites
1998
Retinoic acid and development of the central nervous system
1992
A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish
1997
Eph/Ephrin Signaling Regulates the Mesenchymal-to-Epithelial Transition of the Paraxial Mesoderm during Somite Morphogenesis
2003
Function of the Eph-related kinase rtk1 in patterning of the zebrafish forebrain
1996 Nature
Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain
1994
Zebrafish pax[b] is involved in the formation of the midbrain–hindbrain boundary
1992 Nature
An early developmental role for Eph-ephrin interaction during vertebrate gastrulation
1999
Eph receptors and ephrins: effectors of morphogenesis
1999
Ectopic expression of Hoxa-1 in the zebrafish alters the fate of the mandibular arch neural crest and phenocopies a retinoic acid-induced phenotype
1996
Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos
1991
Analysis of FGF function in normal and no tail zebrafish embryos reveals separate mechanisms for formation of the trunk and the tail
1995
Neuroanatomical and functional analysis of neural tube formation in notochordless Xenopus embryos; laterality of the ventral spinal cord is lost
1991
Organization of connective tissue patterns by dermal fibroblasts in the regenerating axolotl limb
1989
Late effects of retinoic acid on neural crest and aspects of rhombomere identity
1996
Midline signalling is required for Pax gene regulation and patterning of the eyes
1995
Regeneration of symmetrical forelimbs in the axolotl, Ambystoma mexicanum
1980
Reformation of specific neuromuscular connections during axolotl limb regeneration: evidence that the first contacts are correct
1988
Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain
1995
Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud
2002
Spatially regulated expression of three receptor tyrosine kinase genes during gastrulation in the zebrafish
1994
Two Eph receptor tyrosine kinase ligands control axon growth and may be involved in the creation of the retinotectal map in the zebrafish
1997
Evidence for axonal ‘decision regions’ in the axolotl peripheral nervous system
1988
Induction of the mesendoderm in the zebrafish germ ring by yolk cell-derived TGF-β family signals and discrimination of mesoderm and endoderm by FGF
1999
The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain
1997
Exogenous retinoic acid causes specific alterations in the development of the midbrain and hindbrain of the zebrafish embryo including positional respecification of the Mauthner neuron
1995
The effect of healing time on the proximodistal organization of double-half forelimb regenerates in the axolotl, Ambystoma mexicanum
1978
Retinoic acid modifies development of the midbrain-hindbrain border and affects cranial ganglion formation in zebrafish embryos
1991